RNA-protein hybrid ribozymes that efficiently cleave any mRNA independently of the structure of the target RNA
about
Methodological obstacles in knocking down small noncoding RNAsEffective suppression of Dengue fever virus in mosquito cell cultures using retroviral transduction of hammerhead ribozymes targeting the viral genomeIdentification of genes by hybrid ribozymes that couple cleavage activity with the unwinding activity of an endogenous RNA helicase.A functional gene discovery in the Fas-mediated pathway to apoptosis by analysis of transiently expressed randomized hybrid-ribozyme librariesGene discovery by ribozyme and siRNA libraries.Measurements of weak interactions between truncated substrates and a hammerhead ribozyme by competitive kinetic analyses: implications for the design of new and efficient ribozymes with high sequence specificity.Significantly higher activity of a cytoplasmic hammerhead ribozyme than a corresponding nuclear counterpart: engineered tRNAs with an extended 3' end can be exported efficiently and specifically to the cytoplasm in mammalian cellsTargeting mortalin using conventional and RNA-helicase-coupled hammerhead ribozymesShort hairpin type of dsRNAs that are controlled by tRNA(Val) promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells.RNase P: variations and uses.Disruption of dengue virus transmission by mosquitoes.Catalytic nucleic acid enzymes for the study and development of therapies in the central nervous system: Review Article.Rapid selection of accessible and cleavable sites in RNA by Escherichia coli RNase P and random external guide sequencesEffects on RNAi of the tight structure, sequence and position of the targeted region.Efficient trans-cleavage by the Schistosoma mansoni SMalpha1 hammerhead ribozyme in the extreme thermophile Thermus thermophilus.Efficient knockdown of human prnp mRNA expression levels using hybrid hammerhead ribozymes.Relationships between the activities in vitro and in vivo of various kinds of ribozyme and their intracellular localization in mammalian cells.Efficient inhibition of beta-secretase gene expression in HEK293 cells by tRNAVal-driven and CTE-helicase associated hammerhead ribozymes.Protein tyrosine phosphatase LMW-PTP exhibits distinct roles between vascular endothelial and smooth muscle cells.Challenges and Perspectives in Nucleic Acid Enzyme Engineering.Use of a randomized hybrid ribozyme library for identification of genes involved in muscle differentiation.Identification of genes that function in the TNF-alpha-mediated apoptotic pathway using randomized hybrid ribozyme libraries
P2860
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P2860
RNA-protein hybrid ribozymes that efficiently cleave any mRNA independently of the structure of the target RNA
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
RNA-protein hybrid ribozymes t ...... he structure of the target RNA
@ast
RNA-protein hybrid ribozymes t ...... he structure of the target RNA
@en
type
label
RNA-protein hybrid ribozymes t ...... he structure of the target RNA
@ast
RNA-protein hybrid ribozymes t ...... he structure of the target RNA
@en
prefLabel
RNA-protein hybrid ribozymes t ...... he structure of the target RNA
@ast
RNA-protein hybrid ribozymes t ...... he structure of the target RNA
@en
P2093
P2860
P356
P1476
RNA-protein hybrid ribozymes t ...... he structure of the target RNA
@en
P2093
P2860
P304
P356
10.1073/PNAS.091411398
P407
P577
2001-05-01T00:00:00Z