Theiler's virus and Mengo virus induce cross-reactive cytotoxic T lymphocytes restricted to the same immunodominant VP2 epitope in C57BL/6 mice.
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Theiler's virus infection: a model for multiple sclerosisHuman HLA-DR Transgenes Protect Mice from Fatal Virus-Induced Encephalomyelitis and Chronic DemyelinationMicroRNA-Detargeted Mengovirus for Oncolytic VirotherapyAnatomical and Cellular Requirements for the Activation and Migration of Virus-Specific CD8+ T Cells to the Brain during Theiler's Virus InfectionTheiler's virus infection induces a predominant pathogenic CD4+ T cell response to RNA polymerase in susceptible SJL/J miceTheiler's viruses with mutations in loop I of VP1 lead to altered tropism and pathogenesis.Prevalent class I-restricted T-cell response to the Theiler's virus epitope Db:VP2121-130 in the absence of endogenous CD4 help, tumor necrosis factor alpha, gamma interferon, perforin, or costimulation through CD28.Predominant clonal accumulation of CD8+ T cells with moderate avidity in the central nervous systems of Theiler's virus-infected C57BL/6 mice.Direct comparison of demyelinating disease induced by the Daniel's strain and BeAn strain of Theiler's murine encephalomyelitis virus.Theiler's virus infection of perforin-deficient mice.Protection against lethal encephalomyocarditis virus infection in the absence of serum-neutralizing antibodies.H-2D(b-/-) mice are susceptible to persistent infection by Theiler's virusCapsid-specific cytotoxic T lymphocytes recognize three distinct H-2D(b)-restricted regions of the BeAn strain of Theiler's virus and exhibit different cytokine profilesThe majority of infiltrating CD8+ T cells in the central nervous system of susceptible SJL/J mice infected with Theiler's virus are virus specific and fully functional.Transgenic expression of Theiler's murine encephalomyelitis virus genes in H-2(b) mice inhibits resistance to virus-induced demyelinationDifferences in avidity and epitope recognition of CD8(+) T cells infiltrating the central nervous systems of SJL/J mice infected with BeAn and DA strains of Theiler's murine encephalomyelitis virusPreferential induction of protective T cell responses to Theiler's virus in resistant (C57BL/6 x SJL)F1 miceTheiler's murine encephalomyelitis virus as a vaccine candidate for immunotherapy.DA virus mutant H101 has altered CNS pathogenesis and causes immunosuppression.Effective Treatment of Established GL261 Murine Gliomas through Picornavirus Vaccination-Enhanced Tumor Antigen-Specific CD8+ T Cell Responses.The immunodominant CD8+ T cell epitope region of Theiler's virus in resistant C57BL/6 mice is critical for anti-viral immune responses, viral persistence, and binding to the host cells.A Versatile Simple Capture Assay for Assessing the Structural Integrity of MHC Multimer Reagents.An early, abundant cytotoxic T-lymphocyte response against Theiler's virus is critical for preventing viral persistenceAnticapsid immunity level, not viral persistence level, correlates with the progression of Theiler's virus-induced demyelinating disease in viral P1-transgenic mice.Acute hemorrhagic demyelination in a murine model of multiple sclerosis.Gamma interferon is critical for neuronal viral clearance and protection in a susceptible mouse strain following early intracranial Theiler's murine encephalomyelitis virus infection.Cytotoxic T cell response against the chimeric ETV6-AML1 protein in childhood acute lymphoblastic leukemia.Transition from acute to persistent Theiler's virus infection requires active viral replication that drives proinflammatory cytokine expression and chronic demyelinating disease.Neuropathogenesis of Theiler's murine encephalomyelitis virus infection, an animal model for multiple sclerosisPhylogenetic analysis of the species Theilovirus: emerging murine and human pathogens.
P2860
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P2860
Theiler's virus and Mengo virus induce cross-reactive cytotoxic T lymphocytes restricted to the same immunodominant VP2 epitope in C57BL/6 mice.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Theiler's virus and Mengo viru ...... t VP2 epitope in C57BL/6 mice.
@ast
Theiler's virus and Mengo viru ...... t VP2 epitope in C57BL/6 mice.
@en
type
label
Theiler's virus and Mengo viru ...... t VP2 epitope in C57BL/6 mice.
@ast
Theiler's virus and Mengo viru ...... t VP2 epitope in C57BL/6 mice.
@en
prefLabel
Theiler's virus and Mengo viru ...... t VP2 epitope in C57BL/6 mice.
@ast
Theiler's virus and Mengo viru ...... t VP2 epitope in C57BL/6 mice.
@en
P2093
P2860
P1433
P1476
Theiler's virus and Mengo viru ...... t VP2 epitope in C57BL/6 mice.
@en
P2093
Dethlefs S
Larsson-Sciard EL
van der Werf S
P2860
P304
P407
P577
1997-07-01T00:00:00Z