N-terminal constraint activates the catalytic subunit of the DNA-dependent protein kinase in the absence of DNA or Ku.
about
Beyond DNA repair: DNA-PK function in cancerDNA-PK: a dynamic enzyme in a versatile DSB repair pathwayDNA-PKcs, Allostery, and DNA Double-Strand Break Repair: Defining the Structure and Setting the Stage.Interaction between HIV-1 Tat and DNA-PKcs modulates HIV transcription and class switch recombination.Replisome function during replicative stress is modulated by histone h3 lysine 56 acetylation through Ctf4.The N-terminal region of the DNA-dependent protein kinase catalytic subunit is required for its DNA double-stranded break-mediated activation.Restoration of ATM Expression in DNA-PKcs-Deficient Cells Inhibits Signal End Joining.Clustered DNA damage induces pan-nuclear H2AX phosphorylation mediated by ATM and DNA-PKDNA double strand break repair via non-homologous end-joining.Polo-like kinase 1 (PLK1) and protein phosphatase 6 (PP6) regulate DNA-dependent protein kinase catalytic subunit (DNA-PKcs) phosphorylation in mitosis.Cryo-EM structure of human DNA-PK holoenzyme.Akt1 and Akt3 but not Akt2 through interaction with DNA-PKcs stimulate proliferation and post-irradiation cell survival of K-RAS-mutated cancer cells.Protein phosphatase 1 and phosphatase 1 nuclear targeting subunit-dependent regulation of DNA-dependent protein kinase and non-homologous end joining.DNA-PKcs structure suggests an allosteric mechanism modulating DNA double-strand break repair.
P2860
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P2860
N-terminal constraint activates the catalytic subunit of the DNA-dependent protein kinase in the absence of DNA or Ku.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
N-terminal constraint activate ...... e in the absence of DNA or Ku.
@ast
N-terminal constraint activate ...... e in the absence of DNA or Ku.
@en
type
label
N-terminal constraint activate ...... e in the absence of DNA or Ku.
@ast
N-terminal constraint activate ...... e in the absence of DNA or Ku.
@en
prefLabel
N-terminal constraint activate ...... e in the absence of DNA or Ku.
@ast
N-terminal constraint activate ...... e in the absence of DNA or Ku.
@en
P2860
P356
P1476
N-terminal constraint activate ...... se in the absence of DNA or Ku
@en
P2093
Katheryn Meek
Susan P Lees-Miller
P2860
P304
P356
10.1093/NAR/GKR1211
P407
P577
2011-12-13T00:00:00Z