Pathogenesis of simian immunodeficiency virus encephalitis: viral determinants of neurovirulence
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Human immunodeficiency virus infection of human astrocytes disrupts blood-brain barrier integrity by a gap junction-dependent mechanismDuplicated sequence motif in the long terminal repeat of maedi-visna virus extends cell tropism and is associated with neurovirulenceDevelopment and characterization of positively selected brain-adapted SIV.Unraveling the pathogenesis of HIV peripheral neuropathy: insights from a simian immunodeficiency virus macaque modelPaving the path to HIV neurotherapy: Predicting SIV CNS diseaseMacrophages relate presynaptic and postsynaptic damage in simian immunodeficiency virus encephalitis.V3 recombinants indicate a central role for CCR5 as a coreceptor in tissue infection by human immunodeficiency virus type 1.Human immunodeficiency virus neurotropism: an analysis of viral replication and cytopathicity for divergent strains in monocytes and microglia.Isolation and characterization of a neuropathogenic simian immunodeficiency virus derived from a sooty mangabey.Neuronal death induced by brain-derived human immunodeficiency virus type 1 envelope genes differs between demented and nondemented AIDS patientsNeurovirulence in feline immunodeficiency virus-infected neonatal cats is viral strain specific and dependent on systemic immune suppression.Reduced genetic diversity in lymphoid and central nervous system tissues and selection-induced tissue-specific compartmentalization of neuropathogenic SIVsmmFGb during acute infection.High viral load in the cerebrospinal fluid and brain correlates with severity of simian immunodeficiency virus encephalitis.The level of CD4 expression limits infection of primary rhesus monkey macrophages by a T-tropic simian immunodeficiency virus and macrophagetropic human immunodeficiency viruses.Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity.Identification of shared populations of human immunodeficiency virus type 1 infecting microglia and tissue macrophages outside the central nervous system.Suboptimal nucleotides in the infectious, pathogenic simian immunodeficiency virus clone SIVmac239.Highly productive infection with pseudotyped human immunodeficiency virus type 1 (HIV-1) indicates no intracellular restrictions to HIV-1 replication in primary human astrocytes.Development and characterization of an in vivo pathogenic molecular clone of equine infectious anemia virus.Neuropathogenic SIVsmmFGb genetic diversity and selection-induced tissue-specific compartmentalization during chronic infection and temporal evolution of viral genes in lymphoid tissues and regions of the central nervous system.HIV subtype D is associated with dementia, compared with subtype A, in immunosuppressed individuals at risk of cognitive impairment in Kampala, Uganda.Variation in the biological properties of HIV-1 R5 envelopes: implications of envelope structure, transmission and pathogenesis.Envelope gene-mediated neurovirulence in feline immunodeficiency virus infection: induction of matrix metalloproteinases and neuronal injury.Increased CCR5 affinity and reduced CCR5/CD4 dependence of a neurovirulent primary human immunodeficiency virus type 1 isolate.Cardiomyocytes undergo apoptosis in human immunodeficiency virus cardiomyopathy through mitochondrion- and death receptor-controlled pathwaysLongitudinal analysis of monocyte/macrophage infection in simian immunodeficiency virus-infected, CD8+ T-cell-depleted macaques that develop lentiviral encephalitis.In vitro and animal models of human immunodeficiency virus infection of the central nervous systemLentiviral neuropathogenesis: comparative neuroinvasion, neurotropism, neurovirulence, and host neurosusceptibilityResting CD4+ T lymphocytes but not thymocytes provide a latent viral reservoir in a simian immunodeficiency virus-Macaca nemestrina model of human immunodeficiency virus type 1-infected patients on highly active antiretroviral therapy.A simian immunodeficiency virus-infected macaque model to study viral reservoirs that persist during highly active antiretroviral therapy.Human immunodeficiency virus type 1 envelope-mediated neuronal death: uncoupling of viral replication and neurotoxicityExpression of simian immunodeficiency virus (SIV) nef in astrocytes during acute and terminal infection and requirement of nef for optimal replication of neurovirulent SIV in vitro.The HIV Env variant N283 enhances macrophage tropism and is associated with brain infection and dementia.Dysregulation of mitogen-activated protein kinase signaling pathways in simian immunodeficiency virus encephalitis.Induction of cell-cycle regulators in simian immunodeficiency virus encephalitis.Pathogenesis of simian immunodeficiency virus pneumonia: an immunopathological response to virus.Pathogenesis of SIV encephalitis. Selection and replication of neurovirulent SIVNeuropathology of wild-type and nef-attenuated T cell tropic simian immunodeficiency virus (SIVmac32H) and macrophage tropic neurovirulent SIVmac17E-Fr in cynomolgus macaques.Molecular and biological characterization of a neurovirulent molecular clone of simian immunodeficiency virusInduction of antibody-mediated neutralization in SIVmac239 by a naturally acquired V3 mutation.
P2860
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P2860
Pathogenesis of simian immunodeficiency virus encephalitis: viral determinants of neurovirulence
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Pathogenesis of simian immunod ...... determinants of neurovirulence
@ast
Pathogenesis of simian immunod ...... determinants of neurovirulence
@en
type
label
Pathogenesis of simian immunod ...... determinants of neurovirulence
@ast
Pathogenesis of simian immunod ...... determinants of neurovirulence
@en
prefLabel
Pathogenesis of simian immunod ...... determinants of neurovirulence
@ast
Pathogenesis of simian immunod ...... determinants of neurovirulence
@en
P2093
P2860
P1433
P1476
Pathogenesis of simian immunod ...... determinants of neurovirulence
@en
P2093
A M Amedee
J E Clements
J L Mankowski
J P Spelman
L M Kirstein
M Murphey-Corb
M T Flaherty
P2860
P304
P407
P577
1997-08-01T00:00:00Z