Analysis of envelope changes acquired by SIVmac239 during neuroadaption in rhesus macaques.
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ChemR23, a putative chemoattractant receptor, is expressed in monocyte-derived dendritic cells and macrophages and is a coreceptor for SIV and some primary HIV-1 strainsDevelopment and characterization of positively selected brain-adapted SIV.Viral genetic evolution in macaques infected with molecularly cloned simian immunodeficiency virus correlates with the extent of persistent viremia.Simian immunodeficiency virus utilizes human and sooty mangabey but not rhesus macaque STRL33 for efficient entry.Mechanisms for adaptation of simian immunodeficiency virus to replication in alveolar macrophagesHigh viral load in the cerebrospinal fluid and brain correlates with severity of simian immunodeficiency virus encephalitis.The level of CD4 expression limits infection of primary rhesus monkey macrophages by a T-tropic simian immunodeficiency virus and macrophagetropic human immunodeficiency viruses.Kinetic rates of antibody binding correlate with neutralization sensitivity of variant simian immunodeficiency virus strainsEmergence of CD4 independence envelopes and astrocyte infection in R5 simian-human immunodeficiency virus model of encephalitis.Infectious molecular clones from a simian immunodeficiency virus-infected rapid-progressor (RP) macaque: evidence of differential selection of RP-specific envelope mutations in vitro and in vivoRapid progression to simian AIDS can be accompanied by selection of CD4-independent gp120 variants with impaired ability to bind CD4.Escape in one of two cytotoxic T-lymphocyte epitopes bound by a high-frequency major histocompatibility complex class I molecule, Mamu-A*02: a paradigm for virus evolution and persistence?Characterization of simian immunodeficiency virus (SIV) that induces SIV encephalitis in rhesus macaques with high frequency: role of TRIM5 and major histocompatibility complex genotypes and early entry to the brainUnique pattern of convergent envelope evolution in simian immunodeficiency virus-infected rapid progressor macaques: association with CD4-independent usage of CCR5.Cell tropism of simian immunodeficiency virus in culture is not predictive of in vivo tropism or pathogenesisRemoval of N-linked glycosylation sites in the V1 region of simian immunodeficiency virus gp120 results in redirection of B-cell responses to V3.Pathogenesis of simian immunodeficiency virus pneumonia: an immunopathological response to virus.Pathogenesis of SIV encephalitis. Selection and replication of neurovirulent SIVTransfer of neuropathogenic simian immunodeficiency virus with naturally infected microglia.Simian immunodeficiency virus SIVmac chimeric virus whose env gene was derived from SIV-encephalitic brain is macrophage-tropic but not neurovirulent.Genotypic selection of simian immunodeficiency virus in macaque infants infected transplacentallyUnique pathology in simian immunodeficiency virus-infected rapid progressor macaques is consistent with a pathogenesis distinct from that of classical AIDS.A molecularly cloned, pathogenic, neutralization-resistant simian immunodeficiency virus, SIVsmE543-3.Molecular and biological characterization of a neurovirulent molecular clone of simian immunodeficiency virusPathogenesis of simian immunodeficiency virus encephalitis: viral determinants of neurovirulenceInduction of antibody-mediated neutralization in SIVmac239 by a naturally acquired V3 mutation.Dynamic evolution of antibody populations in a rhesus macaque infected with attenuated simian immunodeficiency virus identified by surface plasmon resonance.Differential utilization of CCR5 by macrophage and T cell tropic simian immunodeficiency virus strainsSpontaneous substitutions in the vicinity of the V3 analog affect cell tropism and pathogenicity of simian immunodeficiency virus.Extensive envelope heterogeneity of simian immunodeficiency virus in tissues from infected macaques.Human immunodeficiency virus type 1 infection increases the in vivo capacity of peripheral monocytes to cross the blood-brain barrier into the brain and the in vivo sensitivity of the blood-brain barrier to disruption by lipopolysaccharide.A single amino acid change and truncated TM are sufficient for simian immunodeficiency virus to enter cells using CCR5 in a CD4-independent pathway.Virus-host interaction in the simian immunodeficiency virus-infected brainIntrathecal humoral responses are inversely associated with the frequency of simian immunodeficiency virus macrophage-tropic variants in the central nervous systemNeurovirulent simian immunodeficiency virus infection induces neuronal, endothelial, and glial apoptosisRole of microglial cells in selective replication of simian immunodeficiency virus genotypes in the brainGradient of microglial activation in the brain of SIV infected macaques.Cross-protective immune responses induced in rhesus macaques by immunization with attenuated macrophage-tropic simian immunodeficiency virus.Use of helper-free replication-defective simian immunodeficiency virus-based vectors to study macrophage and T tropism: evidence for distinct levels of restriction in primary macrophages and a T-cell line.Changes in neuron size in cynomolgus macaques infected with various immunodeficiency viruses and poliovirus.
P2860
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P2860
Analysis of envelope changes acquired by SIVmac239 during neuroadaption in rhesus macaques.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Analysis of envelope changes a ...... roadaption in rhesus macaques.
@en
type
label
Analysis of envelope changes a ...... roadaption in rhesus macaques.
@en
prefLabel
Analysis of envelope changes a ...... roadaption in rhesus macaques.
@en
P2093
P356
P1433
P1476
Analysis of envelope changes a ...... roadaption in rhesus macaques.
@en
P2093
Anderson MG
Clements JE
P304
P356
10.1006/VIRO.1993.1413
P407
P577
1993-08-01T00:00:00Z