PDGF enhances store-operated Ca2+ entry by upregulating STIM1/Orai1 via activation of Akt/mTOR in human pulmonary arterial smooth muscle cells.
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Orai1 calcium channels in the vasculatureStore-operated Ca2+ entry (SOCE) regulates melanoma proliferation and cell migrationStore-operated calcium entry and diabetic complicationsRegulation of cellular communication by signaling microdomains in the blood vessel wall.Long-term mTOR inhibitors administration evokes altered calcium homeostasis and platelet dysfunction in kidney transplant patients.PK10453, a nonselective platelet-derived growth factor receptor inhibitor, prevents the progression of pulmonary arterial hypertension.Enhanced Orai1 and STIM1 expression as well as store operated Ca2+ entry in therapy resistant ovary carcinoma cells.Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension.Upregulated expression of STIM2, TRPC6, and Orai2 contributes to the transition of pulmonary arterial smooth muscle cells from a contractile to proliferative phenotype.Na(+)/H(+) exchange and hypoxic pulmonary hypertension.Fructus Corni extract-induced neuritogenesis in PC12 cells is associated with the suppression of stromal interaction molecule 1 expression and inhibition of Ca(2+) influx.Pathogenic role of store-operated and receptor-operated ca(2+) channels in pulmonary arterial hypertension.Exogenous spermine inhibits the proliferation of human pulmonary artery smooth muscle cells caused by chemically-induced hypoxia via the suppression of the ERK1/2- and PI3K/AKT-associated pathways.Regulation of ca(2+) signaling in pulmonary hypertension.Orai channel-mediated Ca2+ signals in vascular and airway smooth muscle.Pathogenic role of calcium-sensing receptors in the development and progression of pulmonary hypertension.Conformation of ryanodine receptor-2 gates store-operated calcium entry in rat pulmonary arterial myocytes.Signal transduction in the development of pulmonary arterial hypertensionCalpain-2 activates Akt via TGF-β1-mTORC2 pathway in pulmonary artery smooth muscle cellsOrai3 constitutes a native store-operated calcium entry that regulates non small cell lung adenocarcinoma cell proliferationSTIM1/Orai1-mediated SOCE: current perspectives and potential roles in cardiac function and pathologySKF-96365 activates cytoprotective autophagy to delay apoptosis in colorectal cancer cells through inhibition of the calcium/CaMKIIγ/AKT-mediated pathway.mTORC1 enhancement of STIM1-mediated store-operated Ca2+ entry constrains tuberous sclerosis complex-related tumor development.Emerging roles for native Orai Ca2+ channels in cardiovascular diseaseThe serum- & glucocorticoid-inducible kinase in the regulation of platelet function.From contraction to gene expression: nanojunctions of the sarco/endoplasmic reticulum deliver site- and function-specific calcium signals.The first Keystone Symposia Conference on pulmonary vascular isease and right ventricular dysfunction: Current concepts and future therapies.Phenotypic and functional changes in dermal primary fibroblasts isolated from intrinsically aged human skin.Role of Akt signaling pathway in delayed cerebral vasospasm after subarachnoid hemorrhage in rats.Hydrogen peroxide is a critical regulator of the hypoxia-induced alterations of store-operated Ca2+ entry into rat pulmonary arterial smooth muscle cells.Hypoxic pulmonary vasoconstriction, carotid body function and erythropoietin production in adult rats perinatally exposed to hyperoxia.Cardiovascular and Hemostatic Disorders: Role of STIM and Orai Proteins in Vascular Disorders.STIM2 (Stromal Interaction Molecule 2)-Mediated Increase in Resting Cytosolic Free Ca2+ Concentration Stimulates PASMC Proliferation in Pulmonary Arterial Hypertension.Imatinib attenuates hypoxia-induced pulmonary arterial hypertension pathology via reduction in 5-hydroxytryptamine through inhibition of tryptophan hydroxylase 1 expression.JAK-STAT signaling and the atrial fibrillation promoting fibrotic substrate.Revisiting the Role of TRP, Orai, and ASIC Channels in the Pulmonary Arterial Response to Hypoxia.Inhibition of Sarco-Endoplasmic Reticulum Ca2+ ATPase Extends the Lifespan in C. elegans Worms.
P2860
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P2860
PDGF enhances store-operated Ca2+ entry by upregulating STIM1/Orai1 via activation of Akt/mTOR in human pulmonary arterial smooth muscle cells.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
PDGF enhances store-operated C ...... arterial smooth muscle cells.
@ast
PDGF enhances store-operated C ...... arterial smooth muscle cells.
@en
type
label
PDGF enhances store-operated C ...... arterial smooth muscle cells.
@ast
PDGF enhances store-operated C ...... arterial smooth muscle cells.
@en
prefLabel
PDGF enhances store-operated C ...... arterial smooth muscle cells.
@ast
PDGF enhances store-operated C ...... arterial smooth muscle cells.
@en
P2093
P2860
P1476
PDGF enhances store-operated C ...... y arterial smooth muscle cells
@en
P2093
Aiko Ogawa
Amy L Firth
Jason X-J Yuan
Mary V Maliakal
P2860
P304
P356
10.1152/AJPCELL.00337.2011
P577
2011-10-26T00:00:00Z