ErbB2 activation upregulates glutaminase 1 expression which promotes breast cancer cell proliferation
about
Glutamine promotes ovarian cancer cell proliferation through the mTOR/S6 pathway.Survival analyses correlate stanniocalcin 2 overexpression to poor prognosis of nasopharyngeal carcinomas.Dysregulation of Blimp1 transcriptional repressor unleashes p130Cas/ErbB2 breast cancer invasion.From Krebs to clinic: glutamine metabolism to cancer therapy.Mesenchymal phenotype predisposes lung cancer cells to impaired proliferation and redox stress in response to glutaminase inhibitionTargeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis.The oncogenic transcription factor c-Jun regulates glutaminase expression and sensitizes cells to glutaminase-targeted therapy.Structural basis for exploring the allosteric inhibition of human kidney type glutaminase.Selenite inhibits glutamine metabolism and induces apoptosis by regulating GLS1 protein degradation via APC/C-CDH1 pathway in colorectal cancer cells.Pheochromocytoma: Gasping for Air.Targeting Glutamine Induces Apoptosis: A Cancer Therapy Approach.Her2 oncogene transformation enhances 5-aminolevulinic acid-mediated protoporphyrin IX production and photodynamic therapy response.Glutaminase and poly(ADP-ribose) polymerase inhibitors suppress pyrimidine synthesis and VHL-deficient renal cancers.T Helper Cell Activation and Expansion Is Sensitive to Glutaminase Inhibition under Both Hypoxic and Normoxic Conditions.Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancerThe receptor tyrosine kinase EphA2 promotes glutamine metabolism in tumors by activating the transcriptional coactivators YAP and TAZ.In Vivo PET Assay of Tumor Glutamine Flux and Metabolism: In-Human Trial of 18F-(2S,4R )-4-Fluoroglutamine.Phosphorylation of glutaminase by PKCε is essential for its enzymatic activity and critically contributes to tumorigenesis.Inhibition of Glycolysis and Glutaminolysis: Emerging Drug Discovery Approach to Combat Cancer.Global metabolite profiling analysis of lipotoxicity in HER2/neu-positive breast cancer cells.Cooperative STAT/NF-κB signaling regulates lymphoma metabolic reprogramming and aberrant GOT2 expression.Downregulation of GLS2 in glioblastoma cells is related to DNA hypermethylation but not to the p53 status.Nuclear factor-κB p65 regulates glutaminase 1 expression in human hepatocellular carcinoma.Oncogenic transformation of normal breast epithelial cells co-cultured with cancer cells
P2860
Q30371587-FB76023C-00A4-41E5-BB23-A3A4A78C115FQ33587519-494AEBBC-1C03-484B-95D9-4498A8D0A5CFQ33682041-011905C4-16C9-4E39-A20A-13EF6B97409CQ33834498-B321D3E2-5552-41BB-9864-C4EF73440FCAQ34691457-28CF13F0-6E36-4E09-B401-ED84D293A076Q35836097-4FD6FB1C-67DC-46E3-A7B3-63CFBB0BD027Q36815149-595611DE-5D8E-44D2-A668-391AAD5EEB2EQ37628958-2BA79C79-E0B4-4900-9766-5C2B9E0EF138Q37745850-A9D3B850-5F82-4C8A-9943-D08742E60804Q38542150-000314FC-40CC-4BF5-A99E-D832C15EF8AAQ38592248-DA31FF17-A414-4D5F-BC25-3DE997F715B2Q39487686-B9DA2A1E-C3FB-4C9C-A0F7-D4F38D964288Q41887078-40F12FA2-EEBB-40E3-A00A-CD7E9FA99FE2Q41943060-9204FDD3-A2B9-4971-9EBD-CF3BC96C6607Q42283243-E53D53A5-19EC-4A59-9942-9484C2B9E35FQ47326513-35E7AB46-7EC9-46B0-92B8-65949C64DABCQ48125324-C3BF358A-FD3C-4518-80CF-2BE6F8C86D32Q52668550-1F0447FB-226C-4A46-957C-0C630493D035Q54978523-684EA998-5581-4015-A660-0A3A5E22F9ABQ55284992-D73F23F9-C8B9-4DE7-9BA4-1A1DBAC6CA71Q55386824-33B12062-F9D5-4BF9-8E20-2EA06D496DFFQ55459904-32270F91-B322-4BF5-A6E3-EE9D959A9B98Q55497559-65612135-0B8D-4DD2-80EE-077ECBBFA95DQ58721230-FB650692-A33A-4464-AAE6-E0D3BC240921
P2860
ErbB2 activation upregulates glutaminase 1 expression which promotes breast cancer cell proliferation
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
ErbB2 activation upregulates g ...... east cancer cell proliferation
@ast
ErbB2 activation upregulates g ...... east cancer cell proliferation
@en
type
label
ErbB2 activation upregulates g ...... east cancer cell proliferation
@ast
ErbB2 activation upregulates g ...... east cancer cell proliferation
@en
prefLabel
ErbB2 activation upregulates g ...... east cancer cell proliferation
@ast
ErbB2 activation upregulates g ...... east cancer cell proliferation
@en
P2093
P2860
P356
P1476
ErbB2 activation upregulates g ...... east cancer cell proliferation
@en
P2093
Chenguang Wang
Clarissa Chu
Nianli Sang
P2860
P304
P356
10.1002/JCB.24684
P50
P577
2014-03-01T00:00:00Z