Positive lysosomal modulation as a unique strategy to treat age-related protein accumulation diseases
about
The lysosome: from waste bag to potential therapeutic targetMacrophage derived cystatin B/cathepsin B in HIV replication and neuropathogenesisLysosomal Re-acidification Prevents Lysosphingolipid-Induced Lysosomal Impairment and Cellular ToxicityPodocytes degrade endocytosed albumin primarily in lysosomesTrehalose reverses cell malfunction in fibroblasts from normal and Huntington's disease patients caused by proteosome inhibition.Z-Phe-Ala-diazomethylketone (PADK) disrupts and remodels early oligomer states of the Alzheimer disease Aβ42 protein.Advances in ion mobility spectrometry-mass spectrometry reveal key insights into amyloid assembly.Protein phosphorylation in neurodegeneration: friend or foe?The role of rab proteins in neuronal cells and in the trafficking of neurotrophin receptors.Prion degradation pathways: Potential for therapeutic intervention.Can Chinese Herbal Medicine Adjunctive Therapy Improve Outcomes of Senile Vascular Dementia? Systematic Review with Meta-analysis of Clinical Trials.Dysregulation and diagnostic potential of microRNA in Alzheimer's disease.Nonpeptidic lysosomal modulators derived from z-phe-ala-diazomethylketone for treating protein accumulation diseases.Aβ42-mediated proteasome inhibition and associated tau pathology in hippocampus are governed by a lysosomal response involving cathepsin B: Evidence for protective crosstalk between protein clearance pathways.The role of NLRP3-CASP1 in inflammasome-mediated neuroinflammation and autophagy dysfunction in manganese-induced, hippocampal-dependent impairment of learning and memory ability.Potential Alzheimer's Disease Therapeutics Among Weak Cysteine Protease Inhibitors Exhibit Mechanistic Differences Regarding Extent of Cathepsin B Up-Regulation and Ability to Block Calpain.
P2860
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P2860
Positive lysosomal modulation as a unique strategy to treat age-related protein accumulation diseases
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Positive lysosomal modulation ...... protein accumulation diseases
@ast
Positive lysosomal modulation ...... protein accumulation diseases
@en
type
label
Positive lysosomal modulation ...... protein accumulation diseases
@ast
Positive lysosomal modulation ...... protein accumulation diseases
@en
prefLabel
Positive lysosomal modulation ...... protein accumulation diseases
@ast
Positive lysosomal modulation ...... protein accumulation diseases
@en
P2093
P2860
P356
P1476
Positive lysosomal modulation ...... protein accumulation diseases
@en
P2093
Ben A Bahr
David Butler
Meagan L Wisniewski
P2860
P304
P356
10.1089/REJ.2011.1282
P407
P577
2012-04-01T00:00:00Z