Lysosomal membrane damage in soluble Abeta-mediated cell death in Alzheimer's disease.
about
Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's diseaseHuman APOE genotype affects intraneuronal Aβ1-42 accumulation in a lentiviral gene transfer modelCathepsin B is a New Drug Target for Traumatic Brain Injury Therapeutics: Evidence for E64d as a Promising Lead Drug CandidateTau clearance mechanisms and their possible role in the pathogenesis of Alzheimer diseaseEarly etiology of Alzheimer's disease: tipping the balance toward autophagy or endosomal dysfunction?Cathepsin L plays a role in quinolinic acid-induced NF-Κb activation and excitotoxicity in rat striatal neuronsImpact of lysosome status on extracellular vesicle content and releaseβ2-Microglobulin amyloid fibril-induced membrane disruption is enhanced by endosomal lipids and acidic pHLysosomal Re-acidification Prevents Lysosphingolipid-Induced Lysosomal Impairment and Cellular ToxicityRole of endocytic inhibitory drugs on internalization of amyloidogenic light chains by cardiac fibroblasts.Membrane localization of beta-amyloid 1-42 in lysosomes: a possible mechanism for lysosome labilizationThe p53 core domain is a molten globule at low pH: functional implications of a partially unfolded structure.Arrestins contribute to amyloid beta-induced cell death via modulation of autophagy and the α7nAch receptor in SH-SY5Y cells.Alzheimer's disease: diverse aspects of mitochondrial malfunctioning.An apolipoprotein E4 fragment can promote intracellular accumulation of amyloid peptide beta 42A synergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer's disease.Oxidative stress and autophagy in the regulation of lysosome-dependent neuron death.Obstructed diffusion in phase-separated supported lipid bilayers: a combined atomic force microscopy and fluorescence recovery after photobleaching approach.Endocannabinoids prevent β-amyloid-mediated lysosomal destabilization in cultured neurons.Asparagine endopeptidase is an innovative therapeutic target for neurodegenerative diseases.Cell surface binding and internalization of aβ modulated by degree of aggregationArsenic induces apoptosis by the lysosomal-mitochondrial pathway in INS-1 cells.Submicromolar Aβ42 reduces hippocampal glutamate receptors and presynaptic markers in an aggregation-dependent manner.Enhancement of BACE1 Activity by p25/Cdk5-Mediated Phosphorylation in Alzheimer's Disease.Endocytosed 2-Microglobulin Amyloid Fibrils Induce Necrosis and Apoptosis of Rabbit Synovial Fibroblasts by Disrupting Endosomal/Lysosomal Membranes: A Novel Mechanism on the Cytotoxicity of Amyloid Fibrils.Lysosomal Enzyme Glucocerebrosidase Protects against Aβ1-42 Oligomer-Induced Neurotoxicity.Positive lysosomal modulation as a unique strategy to treat age-related protein accumulation diseasesThe Role of Neutrophil Proteins on the Amyloid Beta-RAGE Axis.Stable synthetic bacteriochlorins for photodynamic therapy: role of dicyano peripheral groups, central metal substitution (2H, Zn, Pd), and Cremophor EL delivery.Differential regulation of amyloid-β endocytic trafficking and lysosomal degradation by apolipoprotein E isoforms.Apolipoprotein (apo) E4 and Alzheimer's disease: unique conformational and biophysical properties of apoE4 can modulate neuropathology.Intracellular accumulation of aggregated pyroglutamate amyloid beta: convergence of aging and Aβ pathology at the lysosomePeripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease.The E693Delta mutation in amyloid precursor protein increases intracellular accumulation of amyloid beta oligomers and causes endoplasmic reticulum stress-induced apoptosis in cultured cellsOxidative modifications, mitochondrial dysfunction, and impaired protein degradation in Parkinson's disease: how neurons are lost in the Bermuda triangle.Intracellular accumulation of amyloid-Beta - a predictor for synaptic dysfunction and neuron loss in Alzheimer's disease.The role of metallobiology and amyloid-β peptides in Alzheimer's disease.Nuclear and mitochondrial DNA oxidation in Alzheimer's disease.Reciprocal regulation of cholesterol and beta amyloid at the subcellular level in Alzheimer's disease.Recent advances in α-synuclein functions, advanced glycation, and toxicity: implications for Parkinson's disease.
P2860
Q22248091-261988F0-46D4-4984-8F01-AE6FF63F0FBDQ24338827-9B813E78-D4D8-4C10-BEAA-0DC9566335CAQ26782938-9BC27AC1-7B78-410F-9BFD-E79CAFC29B7BQ26995276-A8850869-D863-448E-AEFC-815893422A07Q27026907-5C1E5915-2E43-4D9A-82A2-B57EC235355AQ27305158-84C88DC3-68CA-4021-8237-8210D8D3F7F2Q28076203-6633DFA2-F9C6-4AF5-85F7-DA90F10C1D4CQ28541669-4F59B467-AE33-4AA7-A155-74C018CF73F5Q28555118-E22C1960-6590-4D17-8DD2-C4BFA93360CBQ30478679-B2EAF649-6EA9-4E98-A07B-8FE68A911DA7Q33568378-57D427C3-FBE0-43AD-AC2D-783BE5D783BBQ33594094-144A10E1-0A47-4111-B9EA-CA9E5701F833Q33793982-F572CA95-2E05-436F-BD2F-4F8C98B4C09DQ34007444-0E3FC9E0-2A33-493C-98A9-54B707CF5840Q34020742-07616E3C-E0A5-4EED-86DE-0738DC43D9FEQ34073879-E673825B-B1A3-4CFC-9EA2-03B1C0E52EA8Q34104922-CBB8E5D1-64F2-4296-AF7F-0AAC035F1B49Q34179466-DCD91D0E-2909-4FDB-9E1A-868E1EB2E221Q34352311-31906E81-AECA-4097-9095-2C76EB018682Q34523642-D22081BA-E44A-4A24-8F36-0E6A4430435EQ34572746-A27558A0-8E64-4C3A-8280-83DF7934133EQ35215838-38AED2C0-CBB6-4414-9713-5E2F970FCE42Q35579404-C2459F0B-4EB2-40BA-95D2-5D622F57DADEQ35759083-0DBE8827-71E4-4C1E-A830-0C3D2CAF16DFQ35793465-4797EEB2-D540-4083-B52A-0FF25C5E4333Q35858682-3031A901-3878-493C-B60F-5C470AE7B321Q35904520-279AB310-80E4-40AD-BF0F-4B110B7C1F79Q36146033-BC753CFA-82DF-4C80-89AF-76265457AD56Q36458544-94AE59C0-7060-4A8B-8B8F-8EB560878E7CQ36492888-65350D0B-0F7B-45E4-93A8-B38AB3147BCCQ36546467-D37C2BA5-7F2C-442D-9B24-812CB546CCF1Q36795149-9BC79A8F-C98E-4F1B-949B-2B3D3E4629D6Q37118356-77E3EF6A-4426-438E-95C7-FE32A447293CQ37150804-AD490C6D-447B-4B7F-9F20-FD2AEC6E98AAQ37509229-4D8CD46C-B627-4CD4-B35B-981EA12E4D96Q37765478-4B818F22-248B-486D-91ED-A4FD47BC70B9Q37961769-4E6E4EF9-4428-4EF6-B5AB-E26986126D0BQ37965702-A314A0A3-066D-486C-8E93-5BDCA81333E3Q38012858-88EEE2C4-EF1A-4319-9C19-23947A69763EQ38038126-F43E2B94-6586-493D-BAA1-253918548C1F
P2860
Lysosomal membrane damage in soluble Abeta-mediated cell death in Alzheimer's disease.
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Lysosomal membrane damage in soluble Abeta-mediated cell death in Alzheimer's disease.
@ast
Lysosomal membrane damage in soluble Abeta-mediated cell death in Alzheimer's disease.
@en
type
label
Lysosomal membrane damage in soluble Abeta-mediated cell death in Alzheimer's disease.
@ast
Lysosomal membrane damage in soluble Abeta-mediated cell death in Alzheimer's disease.
@en
prefLabel
Lysosomal membrane damage in soluble Abeta-mediated cell death in Alzheimer's disease.
@ast
Lysosomal membrane damage in soluble Abeta-mediated cell death in Alzheimer's disease.
@en
P2093
P356
P1476
Lysosomal membrane damage in soluble Abeta-mediated cell death in Alzheimer's disease.
@en
P2093
K Ditaranto
T L Tekirian
P356
10.1006/NBDI.2000.0364
P577
2001-02-01T00:00:00Z