Interindividual variability in hepatic expression of the multidrug resistance-associated protein 2 (MRP2/ABCC2): quantification by liquid chromatography/tandem mass spectrometry.
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Cytochrome P450-dependent catabolism of vitamin K: ω-hydroxylation catalyzed by human CYP4F2 and CYP4F11Development of Human Membrane Transporters: Drug Disposition and PharmacogeneticsOptimized approaches for quantification of drug transporters in tissues and cells by MRM proteomicsThe role of transporters in toxicity and diseasePolymorphism of ORM1 is associated with the pharmacokinetics of telmisartanRole of (drug) transporters in imaging in health and disease.Polymorphisms in genes encoding potential mercury transporters and urine mercury concentrations in populations exposed to mercury vapor from gold miningThe role of quantitative ADME proteomics to support construction of physiologically based pharmacokinetic models for use in small molecule drug development.Human Ontogeny of Drug Transporters: Review and Recommendations of the Pediatric Transporter Working GroupPharmacogenomics of Methotrexate Membrane Transport Pathway: Can Clinical Response to Methotrexate in Rheumatoid Arthritis Be Predicted?Mass spectrometry-based targeted proteomics as a tool to elucidate the expression and function of intestinal drug transporters.Stable isotope dilution mass spectrometry for membrane transporter quantitation.Abundance of Hepatic Transporters in Caucasians: A Meta-Analysis.Interindividual variability in hepatic organic anion-transporting polypeptides and P-glycoprotein (ABCB1) protein expression: quantification by liquid chromatography tandem mass spectroscopy and influence of genotype, age, and sexComparison of Heavy Labeled (SIL) Peptide versus SILAC Protein Internal Standards for LC-MS/MS Quantification of Hepatic Drug TransportersThe Promises of Quantitative Proteomics in Precision MedicinePhysiologically based pharmacokinetics joined with in vitro-in vivo extrapolation of ADME: a marriage under the arch of systems pharmacology.Absolute abundance and function of intestinal drug transporters: a prerequisite for fully mechanistic in vitro-in vivo extrapolation of oral drug absorption.Species differences in drug transporters and implications for translating preclinical findings to humans.Prediction of pharmacokinetics and drug-drug interactions when hepatic transporters are involved.Genetic polymorphisms in low-dose methotrexate transporters: current relevance as methotrexate therapeutic outcome biomarkers.Three decades of low-dose methotrexate in rheumatoid arthritis: can we predict toxicity?Translational value of liquid chromatography coupled with tandem mass spectrometry-based quantitative proteomics for in vitro-in vivo extrapolation of drug metabolism and transport and considerations in selecting appropriate techniques.Ontogeny of Hepatic Drug Transporters and Relevance to Drugs Used in Pediatrics.In Vitro Transport Activity and Trafficking of MRP2/ABCC2 Polymorphic Variants.Causes and Consequences of Variability in Drug Transporter Activity in Pediatric Drug Therapy.Impact of Transporter Polymorphisms on Drug Development: Is It Clinically Significant?Abundance of Drug Transporters in the Human Kidney Cortex as Quantified by Quantitative Targeted Proteomics.Ontogeny of Hepatic Drug Transporters as Quantified by LC-MS/MS Proteomics.Role of enterohepatic recirculation in drug disposition: cooperation and complications.Transporter expression in non-cancerous and cancerous liver tissue from donors with hepatocellular carcinoma and chronic hepatitis C infection quantified by LC-MS/MS proteomics.Critical Issues and Optimized Practices in Quantification of Protein Abundance Level to Determine Interindividual Variability in DMET Proteins by LC-MS/MS Proteomics.Proteomic Analysis of the Developmental Trajectory of Human Hepatic Membrane Transporter Proteins in the First Three Months of Life.
P2860
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P2860
Interindividual variability in hepatic expression of the multidrug resistance-associated protein 2 (MRP2/ABCC2): quantification by liquid chromatography/tandem mass spectrometry.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Interindividual variability in ...... aphy/tandem mass spectrometry.
@ast
Interindividual variability in ...... aphy/tandem mass spectrometry.
@en
type
label
Interindividual variability in ...... aphy/tandem mass spectrometry.
@ast
Interindividual variability in ...... aphy/tandem mass spectrometry.
@en
prefLabel
Interindividual variability in ...... aphy/tandem mass spectrometry.
@ast
Interindividual variability in ...... aphy/tandem mass spectrometry.
@en
P2093
P2860
P356
P1476
Interindividual variability in ...... aphy/tandem mass spectrometry.
@en
P2093
Anand K Deo
Bhagwat Prasad
Jashvant D Unadkat
Larissa Balogh
Yurong Lai
P2860
P304
P356
10.1124/DMD.111.043810
P577
2012-02-08T00:00:00Z