A splicing-dependent regulatory mechanism that detects translation signals.
about
Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decayCharacterization of human Smg5/7a: a protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1.Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathwaysComplexes between the nonsense-mediated mRNA decay pathway factor human upf1 (up-frameshift protein 1) and essential nonsense-mediated mRNA decay factors in HeLa cellsMagoh, a human homolog of Drosophila mago nashi protein, is a component of the splicing-dependent exon-exon junction complex.A 3' UTR sequence stabilizes termination codons in the unspliced RNA of Rous sarcoma virus.A single homozygous point mutation in a 3'untranslated region motif of selenoprotein N mRNA causes SEPN1-related myopathyIdentification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4)SMG-2 is a phosphorylated protein required for mRNA surveillance in Caenorhabditis elegans and related to Upf1p of yeastPre-mRNA splicing alters mRNP composition: evidence for stable association of proteins at exon-exon junctionsA specific subset of SR proteins shuttles continuously between the nucleus and the cytoplasmMechanism of escape from nonsense-mediated mRNA decay of human beta-globin transcripts with nonsense mutations in the first exonA nuclear translation-like factor eIF4AIII is recruited to the mRNA during splicing and functions in nonsense-mediated decayRespiratory syncytial virus infection alters surfactant protein A expression in human pulmonary epithelial cells by reducing translation efficiencyIntegration of splicing, transport and translation to achieve mRNA quality control by the nonsense-mediated decay pathway.Nonsense-mediated mRNA decay: from vacuum cleaner to Swiss army knifeA GFP-based reporter system to monitor nonsense-mediated mRNA decayThe Clothes Make the mRNA: Past and Present Trends in mRNP FashionA TALEN-Exon Skipping Design for a Bethlem Myopathy Model in ZebrafishOrganizing principles of mammalian nonsense-mediated mRNA decayA direct intersection between p53 and transforming growth factor beta pathways targets chromatin modification and transcription repression of the alpha-fetoprotein geneRapid deadenylation triggered by a nonsense codon precedes decay of the RNA body in a mammalian cytoplasmic nonsense-mediated decay pathwayThe exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decayOut-of-frame T cell receptor beta transcripts are eliminated by multiple pathways in vivoThe uORF-containing thrombopoietin mRNA escapes nonsense-mediated decay (NMD).Transcripts expressed using a bicistronic vector pIREShyg2 are sensitized to nonsense-mediated mRNA decay.NOD2-C2 - a novel NOD2 isoform activating NF-kappaB in a muramyl dipeptide-independent manner.mRNA surveillance in eukaryotes: kinetic proofreading of proper translation termination as assessed by mRNP domain organization?Frame-disrupting mutations elicit pre-mRNA accumulation independently of frame disruptionBoundary-independent polar nonsense-mediated decay.Intranuclear degradation of nonsense codon-containing mRNAAt least one intron is required for the nonsense-mediated decay of triosephosphate isomerase mRNA: a possible link between nuclear splicing and cytoplasmic translation.Splicing-dependent NMD does not require the EJC in Schizosaccharomyces pombeNuclear history of a pre-mRNA determines the translational activity of cytoplasmic mRNA.RNA surveillance down-regulates expression of nonfunctional kappa alleles and detects premature termination within the last kappa exon.Sequence conservation, relative isoform frequencies, and nonsense-mediated decay in evolutionarily conserved alternative splicing.A premature termination codon interferes with the nuclear function of an exon splicing enhancer in an open reading frame-dependent mannerMultiple splicing defects in an intronic false exon.Nonsense-mediated decay of human HEXA mRNA.Position of premature termination codons determines susceptibility of hERG mutations to nonsense-mediated mRNA decay in long QT syndrome
P2860
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P2860
A splicing-dependent regulatory mechanism that detects translation signals.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
A splicing-dependent regulatory mechanism that detects translation signals.
@ast
A splicing-dependent regulatory mechanism that detects translation signals.
@en
type
label
A splicing-dependent regulatory mechanism that detects translation signals.
@ast
A splicing-dependent regulatory mechanism that detects translation signals.
@en
prefLabel
A splicing-dependent regulatory mechanism that detects translation signals.
@ast
A splicing-dependent regulatory mechanism that detects translation signals.
@en
P2093
P2860
P1433
P1476
A splicing-dependent regulatory mechanism that detects translation signals.
@en
P2093
P2860
P304
P407
P577
1996-11-01T00:00:00Z