Modified deoxyoligonucleotides stable to exonuclease degradation in serum.
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Molecular Selection, Modification and Development of Therapeutic Oligonucleotide AptamersA nicked duplex decamer DNA with a PEG(6) tetherInhibition of human immunodeficiency virus type 1 Rev-Rev-response element complex formation by complementary oligonucleotidesAntisense down-regulation of thymidylate synthase to suppress growth and enhance cytotoxicity of 5-FUdR, 5-FU and Tomudex in HeLa cellsAntisense-induced down-regulation of thymidylate synthase and enhanced cytotoxicity of 5-FUdR in 5-FUdR-resistant HeLa cellsSelf-stabilized antisense oligodeoxynucleotide phosphorothioates: properties and anti-HIV activityInhibitory effects of antisense oligodeoxynucleotides targeting c-myc mRNA on smooth muscle cell proliferation and migrationFit for the Eye: Aptamers in Ocular DisordersSolid-Phase Supports for Oligonucleotide SynthesisSingle-nucleotide polymorphisms can cause different structural folds of mRNA.Intracellular availability of unmodified, phosphorothioated and liposomally encapsulated oligodeoxynucleotides for antisense activity.3'-Exonuclease resistance of DNA oligodeoxynucleotides containing O6-[4-oxo-4-(3-pyridyl)butyl]guanine.An antisense oligodeoxynucleotide targeted to chromaffin cell scinderin gene decreased scinderin levels and inhibited depolarization-induced cortical F-actin disassembly and exocytosis.Multitasking by multivalent circular DNA aptamers.Serum inverts and improves the fluorescence response of an aptamer beacon to various vitamin D analytes.Refilling drug delivery depots through the blood.Kinetics of DNA and RNA Hybridization in Serum and Serum-SDS.Vehicles for oligonucleotide delivery to tumours.Inhibition of the erbB-2 tyrosine kinase receptor in breast cancer cells by phosphoromonothioate and phosphorodithioate antisense oligonucleotides.Stability and functional effectiveness of phosphorothioate modified duplex DNA and synthetic 'mini-genes'.An expression based clonality assay at the human androgen receptor locus (HUMARA) on chromosome X.Inhibition of gene transcription by purine rich triplex forming oligodeoxyribonucleotidesIn vivo stability and kinetics of absorption and disposition of 3' phosphopropyl amine oligonucleotidesDifferential distribution of oligodeoxynucleotides in developing organs with epithelial-mesenchymal interactionsLyn tyrosine kinase signals cell cycle arrest but not apoptosis in B-lineage lymphoma cells.Cell-penetrating and neurotargeting dendritic siRNA nanostructures.Design and Structural Requirements of the Potent and Safe TLR-9 Agonistic Immunomodulator MGN1703.DNA topology influences molecular machine lifetime in human serumEffects of phosphorothioate capping on antisense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus infection.Antisense oligonucleotides in solution or encapsulated in immunoliposomes inhibit replication of HIV-1 by several different mechanisms.The stability of different forms of double-stranded decoy DNA in serum and nuclear extractsIn vitro selection technologies to enhance biomaterial functionality.Intratumoural administration of dendritic cells: hostile environment and help by gene therapy.Bioactive and nuclease-resistant L-DNA ligand of vasopressin.Comparison of several linear fluorophore- and quencher-conjugated oligomer duplexes for stability, fluorescence quenching, and kinetics in vitro and in vivo in miceRational design of novel N-alkyl-N capped biostable RNA nanostructures for efficient long-term inhibition of gene expressionTelomerase regulation of myofibroblast differentiation.3'-modified antisense oligodeoxyribonucleotides complementary to calmodulin mRNA alter behavioral responses in Paramecium.CpG oligodeoxynucleotide nanomedicines for the prophylaxis or treatment of cancers, infectious diseases, and allergiesRadiolabeled oligonucleotides for antisense imaging.
P2860
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P2860
Modified deoxyoligonucleotides stable to exonuclease degradation in serum.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Modified deoxyoligonucleotides stable to exonuclease degradation in serum.
@ast
Modified deoxyoligonucleotides stable to exonuclease degradation in serum.
@en
type
label
Modified deoxyoligonucleotides stable to exonuclease degradation in serum.
@ast
Modified deoxyoligonucleotides stable to exonuclease degradation in serum.
@en
prefLabel
Modified deoxyoligonucleotides stable to exonuclease degradation in serum.
@ast
Modified deoxyoligonucleotides stable to exonuclease degradation in serum.
@en
P2093
P2860
P356
P1476
Modified deoxyoligonucleotides stable to exonuclease degradation in serum.
@en
P2093
P2860
P304
P356
10.1093/NAR/19.4.747
P407
P577
1991-02-01T00:00:00Z