The stability, toxicity and effectiveness of unmodified and phosphorothioate antisense oligodeoxynucleotides in Xenopus oocytes and embryos.
about
Physical properties of oligonucleotides containing phosphoramidate-modified internucleoside linkages.Intracellular availability of unmodified, phosphorothioated and liposomally encapsulated oligodeoxynucleotides for antisense activity.Gold nanoparticles for biology and medicine.Synthetic strategies for studying embryonic development.Targeted elimination of zygotic messages in Xenopus laevis embryos by modified oligonucleotides possessing terminal cationic linkages.The use of antisense oligonucleotides in Xenopus oocytes.p40MO15, a cdc2-related protein kinase involved in negative regulation of meiotic maturation of Xenopus oocytesFertilization of Xenopus oocytes using the host transfer method.Stability and functional effectiveness of phosphorothioate modified duplex DNA and synthetic 'mini-genes'.Hybridization-based detection of Helicobacter pylori at human body temperature using advanced locked nucleic acid (LNA) probes.The H1A histone variant is an in vivo repressor of oocyte-type 5S gene transcription in Xenopus laevis embryos.Effects of phosphorothioate capping on antisense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus infection.Modified deoxyoligonucleotides stable to exonuclease degradation in serum.Triple-strand-forming methylphosphonate oligodeoxynucleotides targeted to mRNA efficiently block protein synthesis.A function for filamentous alpha-smooth muscle actin: retardation of motility in fibroblasts.Viral interleukin 10 is critical for the induction of B cell growth transformation by Epstein-Barr virus.Xenopus oocyte maturation does not require new cyclin synthesis.In vivo antisense oligodeoxynucleotide mapping reveals masked regulatory elements in an mRNA dormant in mouse oocytes.Specificity of antisense oligonucleotides in vivo.ECM-stimulated signaling and actin reorganization in embryonic corneal epithelia are Rho dependentAntisense oligodeoxynucleotides selectively suppress expression of the mutant alpha 2(I) collagen allele in type IV osteogenesis imperfecta fibroblasts. A molecular approach to therapeutics of dominant negative disorders.Xenopus: an ideal system for chemical genetics.Inhibition of HIV-LTR gene expression by oligonucleotides targeted to the TAR elementThe maternal store of zinc finger protein encoding mRNAs in fully grown Xenopus oocytes is not required for early embryogenesis.Antisense oligonucleotide containing an internal, non-nucleotide-based linker promote site-specific cleavage of RNAPositively charged oligonucleotides overcome potassium-mediated inhibition of triplex DNA formation.Characterization of hybridization between synthetic oligodeoxynucleotides and RNA in living cellsBiological availability and nuclease resistance extend the in vitro activity of a phosphorothioate-3'hydroxypropylamine oligonucleotide.The long repetitive polypurine/polypyrimidine sequence (TTCCC)48 forms DNA triplex with PU-PU-PY base triplets in vivo.Synthesis and hybridization properties of oligonucleotides containing 2'-O-modified ribonucleotides.A more efficient and specific strategy in the ablation of mRNA in Xenopus laevis using mixtures of antisense oligos.Increased specificity for antisense oligodeoxynucleotide targeting of RNA cleavage by RNase H using chimeric methylphosphonodiester/phosphodiester structuresDuplex stabilities of phosphorothioate, methylphosphonate, and RNA analogs of two DNA 14-mers.Targeted degradation of mRNA in Xenopus oocytes and embryos directed by modified oligonucleotides: studies of An2 and cyclin in embryogenesis.Regulation of lipoprotein lipase by protein kinase C alpha in 3T3-F442A adipocytes.Antisense Oligodeoxynucleotide Technology: Potential Use for the Treatment of Malignant Brain Tumors.Nuclease resistance and antisense activity of modified oligonucleotides targeted to Ha-ras.Nucleic Acid Polymers with Accelerated Plasma and Tissue Clearance for Chronic Hepatitis B Therapy.Transfer of proalpha2(I) cDNA into cells of a murine model of human Osteogenesis Imperfecta restores synthesis of type I collagen comprised of alpha1(I) and alpha2(I) heterotrimers in vitro and in vivo.Antisense inhibition of chondrocyte CD44 expression leading to cartilage chondrolysis.
P2860
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P2860
The stability, toxicity and effectiveness of unmodified and phosphorothioate antisense oligodeoxynucleotides in Xenopus oocytes and embryos.
description
1990 nî lūn-bûn
@nan
1990 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
The stability, toxicity and ef ...... n Xenopus oocytes and embryos.
@ast
The stability, toxicity and ef ...... n Xenopus oocytes and embryos.
@en
type
label
The stability, toxicity and ef ...... n Xenopus oocytes and embryos.
@ast
The stability, toxicity and ef ...... n Xenopus oocytes and embryos.
@en
prefLabel
The stability, toxicity and ef ...... n Xenopus oocytes and embryos.
@ast
The stability, toxicity and ef ...... n Xenopus oocytes and embryos.
@en
P2093
P2860
P356
P1476
The stability, toxicity and ef ...... n Xenopus oocytes and embryos.
@en
P2093
Jennings CG
Rebagliati M
P2860
P304
P356
10.1093/NAR/18.7.1763
P407
P577
1990-04-01T00:00:00Z