Peroxisome proliferator-activated receptors: mediators of phthalate ester-induced effects in the male reproductive tract? - Wikidata - awgldk - TriplyDB

Peroxisome proliferator-activated receptors: mediators of phthalate ester-induced effects in the male reproductive tract?

Peroxisome proliferator-activated receptors: mediators of phthalate ester-induced effects in the male reproductive tract?

http://www.wikidata.org/entity/Q35924008

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Prenatal phthalate exposure is associated with childhood behavior and executive functioning Exposure to phthalates and breast cancer risk in northern Mexico A critical analysis of the biological impacts of plasticizers on wildlife Concentrations of urinary phthalate metabolites are associated with increased waist circumference and insulin resistance in adult U.S. males Phthalate exposure and childhood obesity Time-response effects of testicular gene expression profiles in Sprague-Dawley male rats treated with di(n-butyl) phthalate Activation of Penile Proadipogenic Peroxisome Proliferator-Activated Receptor gamma with an Estrogen: Interaction with Estrogen Receptor Alpha during Postnatal Development Integrating biomonitoring exposure data into the risk assessment process: phthalates [diethyl phthalate and di(2-ethylhexyl) phthalate] as a case study.Analysis of the heat shock response in mouse liver reveals transcriptional dependence on the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha).Prenatal phthalate exposure and performance on the Neonatal Behavioral Assessment Scale in a multiethnic birth cohort.Association of urinary concentrations of bisphenol A and phthalate metabolites with risk of type 2 diabetes: a prospective investigation in the Nurses' Health Study (NHS) and NHSII cohorts Fragile TIM-4-expressing tissue resident macrophages are migratory and immunoregulatory.Genomic biomarkers of phthalate-induced male reproductive developmental toxicity: a targeted RT-PCR array approach for defining relative potency.Exposure to Endocrine Disruptors and Nuclear Receptors Gene Expression in Infertile and Fertile Men from Italian Areas with Different Environmental Features.The toxicology of ligands for peroxisome proliferator-activated receptors (PPAR).Of mice and men (and rats): phthalate-induced fetal testis endocrine disruption is species-dependent.Peroxisome proliferator-activated receptors as mediators of phthalate-induced effects in the male and female reproductive tract: epidemiological and experimental evidence Proposed mode of action for in utero effects of some phthalate esters on the developing male reproductive tract.Peroxisome proliferator-activated receptor gamma signaling in human sperm physiology Phthalate-induced testicular dysgenesis syndrome: Leydig cell influence.Phthalates impair germ cell number in the mouse fetal testis by an androgen- and estrogen-independent mechanism Interference of pollutants with PPARs: endocrine disruption meets metabolism.Characterization of peroxisome proliferator-activated receptor alpha--independent effects of PPARalpha activators in the rodent liver: di-(2-ethylhexyl) phthalate also activates the constitutive-activated receptor.Gap junctional intercellular communication as a target for liver toxicity and carcinogenicity.Reproductive and developmental toxicity of phthalates.Challenges in the application of quantitative approaches in risk assessment: a case study with di-(2-ethylhexyl)phthalate.Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study.Prenatal phthalate exposure: epigenetic changes leading to lifelong impact on steroid formation.A forum for a highly important and ever-expanding field of study PPARα-dependent cholesterol/testosterone disruption in Leydig cells mediates 2,4-dichlorophenoxyacetic acid-induced testicular toxicity in mice.Dose-dependent short-term study of di-n-butyl phthalate on the testicular antioxidant system of Wistar rats.Comparative time course profiles of phthalate stereoisomers in mice.Identification of transcription factors and coactivators affected by dibutylphthalate interactions in fetal rat testes.Prenatal di-n-butyl phthalate exposure alters reproductive functions at adulthood in male rats.Finding maximal transcriptome differences between reprotoxic and non-reprotoxic phthalate responses in rat testis.Dynamic effect of di-2-(ethylhexyl) phthalate on testicular toxicity: epigenetic changes and their impact on gene expression.An exposure assessment of di-(2-ethylhexyl) phthalate (DEHP) and di-n-butyl phthalate (DBP) in human semen.The PPARα-dependent rodent liver tumor response is not relevant to humans: addressing misconceptions.Prediction of liver toxicity and mode of action using metabolomics in vitro in HepG2 cells.Determination of Dibutyl o‐Phthalate by Antigen‐Coated Competitive Fluorescence Immunoassay

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P2860

Peroxisome proliferator-activated receptors: mediators of phthalate ester-induced effects in the male reproductive tract?

http://www.wikidata.org/entity/Q35924008

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J Christopher Corton

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Paula J Lapinskas

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P2860

Molecular recognition of fatty acids by peroxisome proliferator-activated receptors

Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta)

Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators

SF-1 a key player in the development and differentiation of steroidogenic tissues

Effects of dibutyl phthalate as an environmental endocrine disruptor on gonadal sex differentiation of genetic males of the frog Rana rugosa

Abnormalities of sexual development in male rats with in utero and lactational exposure to the antiandrogenic plasticizer Di(2-ethylhexyl) phthalate.

The plasticizer diethylhexyl phthalate induces malformations by decreasing fetal testosterone synthesis during sexual differentiation in the male rat

Activation of PPARalpha and PPARgamma by environmental phthalate monoesters

Molecular cloning, expression and characterization of human peroxisome proliferator activated receptors gamma 1 and gamma 2

trans-Activation of PPARalpha and PPARgamma by structurally diverse environmental chemicals

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10.1093/TOXSCI/KFI011

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