Multiple prethymic defects underlie age-related loss of T progenitor competence
about
Genetic and Epigenetic Mechanisms That Maintain Hematopoietic Stem Cell FunctionAge-Associated B Cells: A T-bet-Dependent Effector with Roles in Protective and Pathogenic ImmunityGenetic regulation of thymocyte progenitor agingInterleukin-21 accelerates thymic recovery from glucocorticoïd-induced atrophyEnhancing T lineage production in aged mice: a novel function of Foxn1 in the bone marrow nicheFoxn1 is required to maintain the postnatal thymic microenvironment in a dosage-sensitive mannerDeclining expression of a single epithelial cell-autonomous gene accelerates age-related thymic involutionThymic fatness and approaches to enhance thymopoietic fitness in aging.Ageing combines CD4 T cell lymphopenia in secondary lymphoid organs and T cell accumulation in gut associated lymphoid tissue.CCR7 and CCR9 together recruit hematopoietic progenitors to the adult thymusA simple model system enabling human CD34(+) cells to undertake differentiation towards T cellsEffect of aged bone marrow microenvironment on mesenchymal stem cell migration.Aging-associated changes in hematopoiesis and leukemogenesis: what's the connection?Young, proliferative thymic epithelial cells engraft and function in aging thymuses.Fibroblast growth factor-7 partially reverses murine thymocyte progenitor aging by repression of Ink4a.Aging induced decline in T-lymphopoiesis is primarily dependent on status of progenitor niches in the bone marrow and thymusMaintenance of hematopoietic stem cells through regulation of Wnt and mTOR pathways.Causes, consequences, and reversal of immune system aging.TGF-beta signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution.Age-associated changes in immune and inflammatory responses: impact of vitamin E interventionAge-associated changes in the differentiation potentials of human circulating hematopoietic progenitors to T- or NK-lineage cellsImmunity, ageing and cancer.Lin-Sca1+kit- bone marrow cells contain early lymphoid-committed precursors that are distinct from common lymphoid progenitorsDeficient ghrelin receptor-mediated signaling compromises thymic stromal cell microenvironment by accelerating thymic adiposityT-cell reconstitution after allogeneic stem cell transplantation: assessment by measurement of the sjTREC/βTREC ratio and thymic naive T cells.Circulating Hematopoietic Stem and Progenitor Cells in Aging Atomic Bomb Survivors.Axin expression in thymic stromal cells contributes to an age-related increase in thymic adiposity and is associated with reduced thymopoiesis independently of ghrelin signaling.Obesity accelerates thymic aging.The aging immune system and its relationship to the development of chronic obstructive pulmonary disease.Hematopoietic progenitor migration to the adult thymus.From murine to human nude/SCID: the thymus, T-cell development and the missing link.Age-associated B cells: key mediators of both protective and autoreactive humoral responses.
P2860
Q26770001-51883E44-F1B0-491A-A8B1-F0D05E75C2E0Q26795654-0F31041C-1D4D-4D15-9C34-824CED791542Q26853420-C9D36745-641A-4BE3-B85E-ED972039FC1BQ27308759-419E481C-69AF-4430-BA9C-8CDAE7FE2DBDQ28510745-4154652A-56C7-4424-910A-9F33A93E5CC8Q28755731-E5992171-BD97-44EB-8701-1C4DEA4B1E78Q33348652-82480305-1326-4353-875F-974CC15AA760Q33349488-FF7D1430-5A38-4015-AB44-00301356FC8EQ33609175-2D8F394B-F584-4D5D-B18F-EBCAA9C0EFB0Q33722636-63858555-F53B-40AA-A971-8E6B5F30ADB4Q34873999-2DDDFDDC-414A-4922-84F0-A2074C9BF90CQ35096362-685C9990-E25E-4D4B-AD60-EE4FBDB6B6DDQ35188247-0E0429DA-D6E8-47DB-B839-BC6C758F3D53Q35783525-DE0519FC-7DC9-4C49-B4E6-E648075DF029Q36057582-1596AD0D-8FC2-48D8-91BE-6908D2C5EF05Q36380588-D8E250E3-0785-4522-9221-7CA7B19D5EB7Q36457006-CB613080-9250-40B0-AB30-9A99CC3DC7C5Q36638131-E4770225-9CC6-4F31-914E-4DE28B5A8922Q36787592-E0E75219-32D0-470C-8D47-368FC417EADBQ36882253-62F110EF-FC30-4818-A8A3-828DADC21F09Q36920015-5E7B4D4E-6C8E-4903-AC08-4FFDCCECD76BQ36930979-D289E674-B252-498D-AD48-D42A2FDA3FF9Q37000718-BC41BDEE-93B9-4B7E-86F8-ED45D416B90EQ37119813-DD5F5F8A-7474-49A2-8AA4-5B8930E257DFQ37212717-BF3564CE-2BCC-4465-998E-BFFEC9EA4677Q37240915-82C2EECD-611E-4D45-89CF-CC779EC440ACQ37283834-AC42AE6D-7413-49F0-A14A-F641F4B101C6Q37412361-7668D6A1-18EC-4558-900E-8A8CECC2932EQ37637719-1017FC02-29ED-4E1C-B4E4-11F2EDA6CED7Q37830736-6A6B2552-AA48-4007-83FC-0BE89CD3E0F7Q37999788-923C3050-01E0-43F8-A10A-576FC83FAEB5Q38673417-DA5D7F46-C94C-4C99-8C71-406EEEB9A225
P2860
Multiple prethymic defects underlie age-related loss of T progenitor competence
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Multiple prethymic defects underlie age-related loss of T progenitor competence
@ast
Multiple prethymic defects underlie age-related loss of T progenitor competence
@en
type
label
Multiple prethymic defects underlie age-related loss of T progenitor competence
@ast
Multiple prethymic defects underlie age-related loss of T progenitor competence
@en
prefLabel
Multiple prethymic defects underlie age-related loss of T progenitor competence
@ast
Multiple prethymic defects underlie age-related loss of T progenitor competence
@en
P2093
P2860
P1433
P1476
Multiple prethymic defects underlie age-related loss of T progenitor competence
@en
P2093
Avinash Bhandoola
Ivan Maillard
Valerie P Zediak
P2860
P304
P356
10.1182/BLOOD-2007-01-071605
P407
P577
2007-04-24T00:00:00Z