A novel, cleavable peroxisomal targeting signal at the amino-terminus of the rat 3-ketoacyl-CoA thiolase.
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Mutation in PEX16 is causal in the peroxisome-deficient Zellweger syndrome of complementation group D.Identification and characterization of the human orthologue of yeast Pex14pPEX12 interacts with PEX5 and PEX10 and acts downstream of receptor docking in peroxisomal matrix protein importMultiple distinct targeting signals in integral peroxisomal membrane proteinsPhenotype-genotype relationships in peroxisome biogenesis disorders of PEX1-defective complementation group 1 are defined by Pex1p-Pex6p interactionFunctional studies on human Pex7p: subcellular localization and interaction with proteins containing a peroxisome-targeting signal type 2 and other peroxinsTwo proteases, trypsin domain-containing 1 (Tysnd1) and peroxisomal lon protease (PsLon), cooperatively regulate fatty acid β-oxidation in peroxisomal matrixAlternative splicing suggests extended function of PEX26 in peroxisome biogenesis.Identification of a human PTS1 receptor docking protein directly required for peroxisomal protein importPex13p is an SH3 protein of the peroxisome membrane and a docking factor for the predominantly cytoplasmic PTs1 receptorPEX3 functions as a PEX19 docking factor in the import of class I peroxisomal membrane proteinsProtein quaternary structure and expression levels contribute to peroxisomal-targeting-sequence-1-mediated peroxisomal import of human soluble epoxide hydrolaseIdentification of PEX10, the gene defective in complementation group 7 of the peroxisome-biogenesis disordersThe peroxisome biogenesis disorder group 4 gene, PXAAA1, encodes a cytoplasmic ATPase required for stability of the PTS1 receptorIdentification of PEX7 as the second gene involved in Refsum diseasePEX12, the pathogenic gene of group III Zellweger syndrome: cDNA cloning by functional complementation on a CHO cell mutant, patient analysis, and characterization of PEX12pHsp70 regulates the interaction between the peroxisome targeting signal type 1 (PTS1)-receptor Pex5p and PTS1Peroxisome targeting signal type 1 (PTS1) receptor is involved in import of both PTS1 and PTS2: studies with PEX5-defective CHO cell mutants.Pex19p, a farnesylated protein essential for peroxisome biogenesis.Phenotype-genotype relationships in complementation group 3 of the peroxisome-biogenesis disordersPEX13 is mutated in complementation group 13 of the peroxisome-biogenesis disorders.The peroxin pex3p initiates membrane assembly in peroxisome biogenesisDegradation of the cleaved leader peptide of thiolase by a peroxisomal proteinaseGlycosome assembly in trypanosomes: variations in the acceptable degeneracy of a COOH-terminal microbody targeting signalHuman PEX1 cloned by functional complementation on a CHO cell mutant is responsible for peroxisome-deficient Zellweger syndrome of complementation group IAltered expression of ALDP in X-linked adrenoleukodystrophyHuman peroxisomal targeting signal-1 receptor restores peroxisomal protein import in cells from patients with fatal peroxisomal disordersDisruption of a PEX1-PEX6 interaction is the most common cause of the neurologic disorders Zellweger syndrome, neonatal adrenoleukodystrophy, and infantile Refsum diseaseMultiple PEX genes are required for proper subcellular distribution and stability of Pex5p, the PTS1 receptor: evidence that PTS1 protein import is mediated by a cycling receptorMolecular cloning, gene structure and expression profile of two mouse peroxisomal 3-ketoacyl-CoA thiolase genesThe similarity between N-terminal targeting signals for protein import into different organelles and its evolutionary relevancePeroxisomes are required for lipid metabolism and muscle function in Drosophila melanogasterGiant peroxisomes in oleic acid-induced Saccharomyces cerevisiae lacking the peroxisomal membrane protein Pmp27p.The SH3 domain of the Saccharomyces cerevisiae peroxisomal membrane protein Pex13p functions as a docking site for Pex5p, a mobile receptor for the import PTS1-containing proteins.Peb1p (Pas7p) is an intraperoxisomal receptor for the NH2-terminal, type 2, peroxisomal targeting sequence of thiolase: Peb1p itself is targeted to peroxisomes by an NH2-terminal peptide.YHR150w and YDR479c encode peroxisomal integral membrane proteins involved in the regulation of peroxisome number, size, and distribution in Saccharomyces cerevisiaeOverexpression of Pex15p, a phosphorylated peroxisomal integral membrane protein required for peroxisome assembly in S.cerevisiae, causes proliferation of the endoplasmic reticulum membraneSaccharomyces cerevisiae PTS1 receptor Pex5p interacts with the SH3 domain of the peroxisomal membrane protein Pex13p in an unconventional, non-PXXP-related manner.Pmp27 promotes peroxisomal proliferationDynamic changes in the subcellular distribution of Gpd1p in response to cell stress.
P2860
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P2860
A novel, cleavable peroxisomal targeting signal at the amino-terminus of the rat 3-ketoacyl-CoA thiolase.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
A novel, cleavable peroxisomal ...... e rat 3-ketoacyl-CoA thiolase.
@ast
A novel, cleavable peroxisomal ...... e rat 3-ketoacyl-CoA thiolase.
@en
type
label
A novel, cleavable peroxisomal ...... e rat 3-ketoacyl-CoA thiolase.
@ast
A novel, cleavable peroxisomal ...... e rat 3-ketoacyl-CoA thiolase.
@en
prefLabel
A novel, cleavable peroxisomal ...... e rat 3-ketoacyl-CoA thiolase.
@ast
A novel, cleavable peroxisomal ...... e rat 3-ketoacyl-CoA thiolase.
@en
P2093
P2860
P1433
P1476
A novel, cleavable peroxisomal ...... e rat 3-ketoacyl-CoA thiolase.
@en
P2093
A G Bodnar
B W Swinkels
R A Rachubinski
S Subramani
P2860
P304
P407
P577
1991-11-01T00:00:00Z