Inhibition of Mcl-1 promotes senescence in cancer cells: implications for preventing tumor growth and chemotherapy resistance.
about
MCL-1 is modulated in Crohn's disease fibrosis by miR-29b via IL-6 and IL-8MicroRNA-101 targets EZH2, MCL-1 and FOS to suppress proliferation, invasion and stem cell-like phenotype of aggressive endometrial cancer cellsProteomics analysis of normal and senescent NG108-15 cells: GRP78 plays a negative role in cisplatin-induced senescence in the NG108-15 cell line.Targeting mcl-1 for radiosensitization of pancreatic cancers.Structure-Function Analysis of the Mcl-1 Protein Identifies a Novel Senescence-regulating Domain.Broad targeting of resistance to apoptosis in cancer.Anticancer bioactive peptides suppress human colorectal tumor cell growth and induce apoptosis via modulating the PARP-p53-Mcl-1 signaling pathwayParthenolide induces MITF-M downregulation and senescence in patient-derived MITF-M(high) melanoma cell populationsAkt inhibition improves irinotecan treatment and prevents cell emergence by switching the senescence response to apoptosis.GRIM-19: A master regulator of cytokine induced tumor suppression, metastasis and energy metabolism.Raiding the pharmacy: genomic screening identifies known chemotherapies as negative regulators of MCL1.Tumor-derived exosomes induce CD8+ T cell suppressors.Use of a MCL-1 inhibitor alone to de-bulk melanoma and in combination to kill melanoma initiating cells.Mcl-1 regulates reactive oxygen species via NOX4 during chemotherapy-induced senescence.Mcl-1 and tumor cell persistence.Senescence is a Spi1-induced anti-proliferative mechanism in primary hematopoietic cells.RHEB: a potential regulator of chondrocyte phenotype for cartilage tissue regeneration.Beclin 1 restrains tumorigenesis through Mcl-1 destabilization in an autophagy-independent reciprocal manner.
P2860
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P2860
Inhibition of Mcl-1 promotes senescence in cancer cells: implications for preventing tumor growth and chemotherapy resistance.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Inhibition of Mcl-1 promotes s ...... h and chemotherapy resistance.
@ast
Inhibition of Mcl-1 promotes s ...... h and chemotherapy resistance.
@en
type
label
Inhibition of Mcl-1 promotes s ...... h and chemotherapy resistance.
@ast
Inhibition of Mcl-1 promotes s ...... h and chemotherapy resistance.
@en
prefLabel
Inhibition of Mcl-1 promotes s ...... h and chemotherapy resistance.
@ast
Inhibition of Mcl-1 promotes s ...... h and chemotherapy resistance.
@en
P2093
P2860
P356
P1476
Inhibition of Mcl-1 promotes s ...... h and chemotherapy resistance.
@en
P2093
Abeba Demelash
Brian R Gastman
Dhan V Kalvakolanu
Elzbieta Bolesta
John C Papadimitriou
Lukas W Pfannenstiel
Mathew L Lesniewski
Megan Tobin
Shreeram C Nallar
Simon E Schlanger
P2860
P304
P356
10.1128/MCB.06214-11
P407
P577
2012-03-26T00:00:00Z