Native mass spectrometry and ion mobility characterization of trastuzumab emtansine, a lysine-linked antibody drug conjugate.
about
The diverse and expanding role of mass spectrometry in structural and molecular biologyPepsin-Containing Membranes for Controlled Monoclonal Antibody Digestion Prior to Mass Spectrometry Analysis.A HER2 selective theranostic agent for surgical resection guidance and photodynamic therapy.In-depth structural characterization of Kadcyla® (ado-trastuzumab emtansine) and its biosimilar candidate.Cutting-edge mass spectrometry methods for the multi-level structural characterization of antibody-drug conjugates.Porphyrin modified trastuzumab improves efficacy of HER2 targeted photodynamic therapy of gastric cancer.Insights from native mass spectrometry approaches for top- and middle- level characterization of site-specific antibody-drug conjugates.Strategies and challenges for the next generation of antibody-drug conjugates.New Insights in Tissue Distribution, Metabolism, and Excretion of [3H]-Labeled Antibody Maytansinoid Conjugates in Female Tumor-Bearing Nude Rats.Towards the Analysis of High Molecular Weight Proteins and Protein complexes using TIMS-MS.Dendrimer antibody conjugate to target and image HER-2 overexpressing cancer cells.Compression Ratio Ion Mobility Programming (CRIMP) Accumulation and Compression of Billions of Ions for Ion Mobility-Mass Spectrometry Using Traveling Waves in Structures for Lossless Ion Manipulations (SLIM).Improving theranostics in pancreatic cancer.Parsimonious Charge Deconvolution for Native Mass Spectrometry.Adding a new separation dimension to MS and LC-MS: What is the utility of ion mobility spectrometry?Analytical techniques for the characterization of Antibody Drug Conjugates: Challenges and prospects.Decoration of trastuzumab with short oligonucleotides: synthesis and detailed characterization.Immunoprecipitation middle-up LC-MS for in vivo drug-to-antibody ratio determination for antibody-drug conjugates.The heights of biopharmaceutical complexity and the current reach of analytical instrumentation.Challenges and new frontiers in analytical characterization of antibody-drug conjugates.Evaluation of Ion Mobility-Mass Spectrometry for Comparative Analysis of Monoclonal Antibodies.Use of a charge reducing agent to enable intact mass analysis of cysteine-linked antibody-drug-conjugates by native mass spectrometry.
P2860
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P2860
Native mass spectrometry and ion mobility characterization of trastuzumab emtansine, a lysine-linked antibody drug conjugate.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Native mass spectrometry and i ...... inked antibody drug conjugate.
@ast
Native mass spectrometry and i ...... inked antibody drug conjugate.
@en
type
label
Native mass spectrometry and i ...... inked antibody drug conjugate.
@ast
Native mass spectrometry and i ...... inked antibody drug conjugate.
@en
prefLabel
Native mass spectrometry and i ...... inked antibody drug conjugate.
@ast
Native mass spectrometry and i ...... inked antibody drug conjugate.
@en
P2093
P2860
P356
P1433
P1476
Native mass spectrometry and i ...... inked antibody drug conjugate.
@en
P2093
Alain Beck
Alain Van Dorsselaer
Elsa Wagner-Rousset
Nathalie Corvaïa
Olivier Colas
Thierry Champion
P2860
P304
P356
10.1002/PRO.2666
P577
2015-03-31T00:00:00Z