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What Glues a Homodimer Together: Systematic Analysis of the Stabilizing Effect of an Aromatic Hot Spot in the Protein-Protein Interface of the tRNA-Modifying Enzyme TgtStructure/Function Analysis of Protein-Protein Interactions Developed by the Yeast Pih1 Platform Protein and Its Partners in Box C/D snoRNP AssemblyFunctional and Structural Insights of the Zinc-Finger HIT protein family members Involved in Box C/D snoRNP BiogenesisTCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xLComparative expression study of the endo-G protein coupled receptor (GPCR) repertoire in human glioblastoma cancer stem-like cells, U87-MG cells and non malignant cells of neural origin unveils new potential therapeutic targetsSupramolecular luminescent lanthanide dimers for fluoride sequestering and sensing.Benchmarking quantitative label-free LC-MS data processing workflows using a complex spiked proteomic standard dataset.Native mass spectrometry and ion mobility characterization of trastuzumab emtansine, a lysine-linked antibody drug conjugate.MetAP1 and MetAP2 drive cell selectivity for a potent anti-cancer agent in synergy, by controlling glutathione redox state.Looking for Missing Proteins in the Proteome of Human Spermatozoa: An Update.Computational and Mass-Spectrometry-Based Workflow for the Discovery and Validation of Missing Human Proteins: Application to Chromosomes 2 and 14.Towards integrative structural mass spectrometry: Benefits from hybrid approaches.Cutting-edge mass spectrometry methods for the multi-level structural characterization of antibody-drug conjugates.A combined proteomic and targeted analysis unravels new toxic mechanisms for zinc oxide nanoparticles in macrophages.Insights from native mass spectrometry and ion mobility-mass spectrometry for antibody and antibody-based product characterization.MAPN: First-in-Class Reagent for Kinetically Resolved Thiol-to-Thiol Conjugation.Molecular responses of alveolar epithelial A549 cells to chronic exposure to titanium dioxide nanoparticles: A proteomic view.Characterization of the N-terminal heterogeneities of monoclonal antibodies using in-gel charge derivatization of α-amines and LC-MS/MS.CBTF: new amine-to-thiol coupling reagent for preparation of antibody conjugates with increased plasma stability.Benchmarking sample preparation/digestion protocols reveals tube-gel being a fast and repeatable method for quantitative proteomics.The flexibility of a generic LC-MS/MS method for the quantitative analysis of therapeutic proteins based on human immunoglobulin G and related constructs in animal studies.SMART Digest™ compared with pellet digestion for analysis of human immunoglobulin G1 in rat serum by liquid chromatography tandem mass spectrometry.The use of generic surrogate peptides for the quantitative analysis of human immunoglobulin G1 in pre-clinical species with high-resolution mass spectrometry.Cutting-edge mass spectrometry characterization of originator, biosimilar and biobetter antibodies.Intermolecular recognition of the non-coding RNA 7SK and HEXIM protein in perspective.Time resolved native ion-mobility mass spectrometry to monitor dynamics of IgG4 Fab arm exchange and "bispecific" monoclonal antibody formation.Maltaricin CPN, a new class IIa bacteriocin produced by Carnobacterium maltaromaticum CPN isolated from mould-ripened cheese.Probing Supramolecular Interactions between a Crown Ether-Appended Zinc Phthalocyanine and an Ammonium Group Appended to a C60 Derivative.Innovative native MS methodologies for antibody drug conjugate characterization: High resolution native MS and IM-MS for average DAR and DAR distribution assessment.Dual Data-Independent Acquisition Approach Combining Global HCP Profiling and Absolute Quantification of Key Impurities during Bioprocess Development.An Online Four-Dimensional HIC×SEC-IM×MS Methodology for Proof-of-Concept Characterization of Antibody Drug Conjugates.Structure-Based Identification of HIV-1 Nucleocapsid Protein Inhibitors Active against Wild-Type and Drug-Resistant HIV-1 Strains.Palladium-Catalyzed Chemoselective and Biocompatible Functionalization of Cysteine-Containing Molecules at Room Temperature.Greatwall dephosphorylation and inactivation upon mitotic exit is triggered by PP1.Ion mobility coupled to native mass spectrometry as a relevant tool to investigate extremely small ligand-induced conformational changes.p-Sulfonato-calix[n]arenes inhibit staphylococcal bicomponent leukotoxins by supramolecular interactionsThe H2O2-Resistant Fe–S Redox Switch MitoNEET Acts as a pH Sensor To Repair Stress-Damaged Fe–S ProteinA novel online four-dimensional SECxSEC-IMxMS methodology for characterization of monoclonal antibody size variantsHomodimer Architecture of QTRT2, the Noncatalytic Subunit of the Eukaryotic tRNA-Guanine TransglycosylaseCombining native MS approaches to decipher archaeal box H/ACA ribonucleoprotein particle structure and activity
P50
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P50
description
onderzoeker
@nl
researcher ORCID ID = 0000-0003-4013-4129
@en
name
Sarah Cianférani
@ast
Sarah Cianférani
@en
Sarah Cianférani
@es
Sarah Cianférani
@nl
type
label
Sarah Cianférani
@ast
Sarah Cianférani
@en
Sarah Cianférani
@es
Sarah Cianférani
@nl
prefLabel
Sarah Cianférani
@ast
Sarah Cianférani
@en
Sarah Cianférani
@es
Sarah Cianférani
@nl
P106
P21
P31
P496
0000-0003-4013-4129