Oxidative genome damage and its repair: implications in aging and neurodegenerative diseases. - Wikidata - awgldk - TriplyDB

Oxidative genome damage and its repair: implications in aging and neurodegenerative diseases.

Oxidative genome damage and its repair: implications in aging and neurodegenerative diseases.

http://www.wikidata.org/entity/Q35957287

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Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair Opposing roles of mitochondrial and nuclear PARP1 in the regulation of mitochondrial and nuclear DNA integrity: implications for the regulation of mitochondrial function DNA Damage and Repair in Schizophrenia and Autism: Implications for Cancer Comorbidity and Beyond The Response to Oxidative DNA Damage in Neurons: Mechanisms and Disease Mitochondrial genetics Guanine holes are prominent targets for mutation in cancer and inherited disease WRN is recruited to damaged telomeres via its RQC domain and tankyrase1-mediated poly-ADP-ribosylation of TRF1.Microextraction by Packed Sorbent (MEPS) and Solid-Phase Microextraction (SPME) as Sample Preparation Procedures for the Metabolomic Profiling of Urine.DNA damage responses in central nervous system and age-associated neurodegeneration Essential oils and their constituents as anticancer agents: a mechanistic view.DNA-PK and P38 MAPK: A Kinase Collusion in Alzheimer's Disease?Base excision repair: a critical player in many games APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functions Oligomeric proanthocyanidin protects retinal ganglion cells against oxidative stress-induced apoptosis.8-Oxoguanine DNA glycosylase-1-mediated DNA repair is associated with Rho GTPase activation and α-smooth muscle actin polymerization.AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of mitochondrial DNA integrity in oxidatively stressed endothelial cells in vitro.Histone methylation and aging: lessons learned from model systems.Deficiency in repair of the mitochondrial genome sensitizes proliferating myoblasts to oxidative damage Mitochondrial dysfunction and risk of cancer Hydrogen-rich saline reduces cell death through inhibition of DNA oxidative stress and overactivation of poly (ADP-ribose) polymerase-1 in retinal ischemia-reperfusion injury.Genetic polymorphisms associated with the inflammatory response in bacterial meningitis.Poly(ADP-ribose) protects vascular smooth muscle cells from oxidative DNA damage.DNA and chromosomal damage in coronary artery disease patients.APE2 Zf-GRF facilitates 3'-5' resection of DNA damage following oxidative stress.Coordination of DNA repair by NEIL1 and PARP-1: a possible link to aging Parkinson's disease: a complex interplay of mitochondrial DNA alterations and oxidative stress.Altered DNA base excision repair profile in brain tissue and blood in Alzheimer's disease Base excision repair in the mammalian brain: implication for age related neurodegeneration Human apurinic/apyrimidinic endonuclease 1.Functional interplay between ATM/ATR-mediated DNA damage response and DNA repair pathways in oxidative stress.A review on protein-protein interaction network of APE1/Ref-1 and its associated biological functions.Transplantation and Damage-Associated Molecular Patterns (DAMPs).Ginkgolide B revamps neuroprotective role of apurinic/apyrimidinic endonuclease 1 and mitochondrial oxidative phosphorylation against Aβ25-35 -induced neurotoxicity in human neuroblastoma cells.TDP-43/FUS in motor neuron disease: Complexity and challenges.Analysis of antioxidant and anti-inflammatory activity of silicon in murine macrophages.Genistein alleviates the mitochondria-targeted DNA damage induced by β-amyloid peptides 25-35 in C6 glioma cells.Enforced DNA repair enzymes rescue neurons from apoptosis induced by target deprivation and axotomy in mouse models of neurodegeneration.Activation of GLP-1 Receptor Enhances Neuronal Base Excision Repair via PI3K-AKT-Induced Expression of Apurinic/Apyrimidinic Endonuclease 1 Epigenetics and Oxidative Stress in Aging.A missense MT-ND5 mutation in differentiated Parkinson Disease cytoplasmic hybrid induces ROS-dependent DNA Damage Response amplified by DROSHA.

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P2860

Oxidative genome damage and its repair: implications in aging and neurodegenerative diseases.

http://www.wikidata.org/entity/Q35957287

description

2012 nî lūn-bûn

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Oxidative genome damage and it ...... nd neurodegenerative diseases.

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Oxidative genome damage and it ...... nd neurodegenerative diseases.

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Oxidative genome damage and it ...... nd neurodegenerative diseases.

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Oxidative genome damage and it ...... nd neurodegenerative diseases.

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Oxidative genome damage and it ...... nd neurodegenerative diseases.

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Oxidative genome damage and it ...... nd neurodegenerative diseases.

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J.MAD.2012.01.005

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Mechanisms of Ageing and Development

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Oxidative genome damage and it ...... and neurodegenerative diseases

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Anil K Mantha

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Bartosz Szczesny

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Kishor K Bhakat

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Sankar Mitra

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Tapas K Hazra

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P2860

The human DNA ligase III gene encodes nuclear and mitochondrial proteins

DNA Damage, Aging, and Cancer

Instability and decay of the primary structure of DNA

Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair

Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1

Spinocerebellar ataxia with axonal neuropathy: consequence of a Tdp1 recessive neomorphic mutation?

Human AP endonuclease (APE1/Ref-1) and its acetylation regulate YB-1-p300 recruitment and RNA polymerase II loading in the drug-induced activation of multidrug resistance gene MDR1

The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates

hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup

Discovery of a novel function for human Rad51: maintenance of the mitochondrial genome

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157-168

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scholarly article

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10.1016/J.MAD.2012.01.005

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4

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133

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Muralidhar L. Hegde

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2012-01-31T00:00:00Z

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221813940

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22313689

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neurodegeneration

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3351531

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