Monitoring Conformational Changes in the Receptor Tyrosine Kinase EGFR.

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Monitoring Conformational Changes in the Receptor Tyrosine Kinase EGFR.

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http://www.wikidata.org/entity/Q35962944

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2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

@zh

2016年论文

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name

Monitoring Conformational Changes in the Receptor Tyrosine Kinase EGFR.

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Monitoring Conformational Changes in the Receptor Tyrosine Kinase EGFR.

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Item

label

Monitoring Conformational Changes in the Receptor Tyrosine Kinase EGFR.

@ast

Monitoring Conformational Changes in the Receptor Tyrosine Kinase EGFR.

@en

prefLabel

Monitoring Conformational Changes in the Receptor Tyrosine Kinase EGFR.

@ast

Monitoring Conformational Changes in the Receptor Tyrosine Kinase EGFR.

@en

P1476

Monitoring Conformational Changes in the Receptor Tyrosine Kinase EGFR.

@en

P2093

Christian Becker

http://www.w3.org/2001/XMLSchema#string

Jeffrey R Simard

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Marina Keul

http://www.w3.org/2001/XMLSchema#string

Sinan Öcal

http://www.w3.org/2001/XMLSchema#string

Trang Phan

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P2860

Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface

Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment

Oncogenic mutations counteract intrinsic disorder in the EGFR kinase and promote receptor dimerization

EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib

The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP

BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models

Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain

A new screening assay for allosteric inhibitors of cSrc

High-throughput screening to identify inhibitors which stabilize inactive kinase conformations in p38alpha

Fluorophore Labeled Kinase Detects Ligands That Bind within the MAPK Insert of p38α Kinase

P304

990-994

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P31

scholarly article

P356

10.1002/CBIC.201600115

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Hoang D. Nguyen

Daniel Rauh

P577

2016-03-15T00:00:00Z

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P698

26991964

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