Re-exploring the N-phenylpicolinamide derivatives to develop mGlu4 ligands with improved affinity and in vitro microsomal stability.

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Synthesis and evaluation of N-(methylthiophenyl)picolinamide derivatives as PET radioligands for metabotropic glutamate receptor subtype 4.

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P2860

Re-exploring the N-phenylpicolinamide derivatives to develop mGlu4 ligands with improved affinity and in vitro microsomal stability.

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2015 nî lūn-bûn

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年學術文章

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2015年學術文章

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2015年學術文章

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name

Re-exploring the N-phenylpicol ...... in vitro microsomal stability.

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Re-exploring the N-phenylpicol ...... in vitro microsomal stability.

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Re-exploring the N-phenylpicol ...... in vitro microsomal stability.

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Re-exploring the N-phenylpicol ...... in vitro microsomal stability.

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Re-exploring the N-phenylpicol ...... in vitro microsomal stability.

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Re-exploring the N-phenylpicol ...... in vitro microsomal stability.

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P1476

Re-exploring the N-phenylpicol ...... in vitro microsomal stability.

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P2093

Anna-Liisa Brownell

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Bryan L Roth

http://www.w3.org/2001/XMLSchema#string

Hye-Jin Kang

http://www.w3.org/2001/XMLSchema#string

Ji-Kyung Choi

http://www.w3.org/2001/XMLSchema#string

Kun-Eek Kil

http://www.w3.org/2001/XMLSchema#string

Xi-Ping Huang

http://www.w3.org/2001/XMLSchema#string

Zhaoda Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

Synthesis and evaluation of a series of heterobiarylamides that are centrally penetrant metabotropic glutamate receptor 4 (mGluR4) positive allosteric modulators (PAMs)

The glutamate story

Glutamate receptor function in learning and memory

Distribution and synaptic localisation of the metabotropic glutamate receptor 4 (mGluR4) in the rodent CNS

Pharmacology and functions of metabotropic glutamate receptors

A novel selective metabotropic glutamate receptor 4 agonist reveals new possibilities for developing subtype selective ligands with therapeutic potential.

Characterization of the novel positive allosteric modulator of the metabotropic glutamate receptor 4 ADX88178 in rodent models of neuropsychiatric disorders.

Tricyclic thiazolopyrazole derivatives as metabotropic glutamate receptor 4 positive allosteric modulators.

Radiosynthesis and evaluation of an 18F-labeled positron emission tomography (PET) radioligand for metabotropic glutamate receptor subtype 4 (mGlu4).

The ligand paradox between affinity and efficacy: can you be there and not make a difference?

P304

3956-3960

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scholarly article

P356

10.1016/J.BMCL.2015.07.031

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English

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Pekka K Poutiainen

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2015-07-17T00:00:00Z

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26231155

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P932

4539532

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Re-exploring the N-phenylpicolinamide derivatives to develop mGlu4 ligands with improved affinity and in vitro microsomal stability.

about

P2860

P2860

Re-exploring the N-phenylpicolinamide derivatives to develop mGlu4 ligands with improved affinity and in vitro microsomal stability.

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P1433

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P932