A sphingosine kinase inhibitor combined with temozolomide induces glioblastoma cell death through accumulation of dihydrosphingosine and dihydroceramide, endoplasmic reticulum stress and autophagy
about
Targeting autophagy to sensitive glioma to temozolomide treatmentStrategies of temozolomide in future glioblastoma treatmentA Novel Computer-Assisted Approach to evaluate Multicellular Tumor Spheroid Invasion Assay.Loss of neutral ceramidase protects cells from nutrient- and energy -deprivation-induced cell death.EMC6/TMEM93 suppresses glioblastoma proliferation by modulating autophagyThe Sphingosine Kinase 2 Inhibitor ABC294640 Reduces the Growth of Prostate Cancer Cells and Results in Accumulation of Dihydroceramides In Vitro and In Vivo.p73 regulates basal and starvation-induced liver metabolism in vivo.MIR517C inhibits autophagy and the epithelial-to-mesenchymal (-like) transition phenotype in human glioblastoma through KPNA2-dependent disruption of TP53 nuclear translocationEssential role for acid sphingomyelinase-inhibited autophagy in melanoma response to cisplatin.Cerebrovascular Angiogenic Reprogramming upon LRP1 Repression: Impact on Sphingosine-1-Phosphate-Mediated Signaling in Brain Endothelial Cell Chemotactism.Jaspine B induces nonapoptotic cell death in gastric cancer cells independently of its inhibition of ceramide synthase.Comparative analysis of the effects of a sphingosine kinase inhibitor to temozolomide and radiation treatment on glioblastoma cell lines.3-Ketosphinganine provokes the accumulation of dihydroshingolipids and induces autophagy in cancer cells.Interference with distinct steps of sphingolipid synthesis and signaling attenuates proliferation of U87MG glioma cells.Melatonin prevents deregulation of the sphingosine kinase/sphingosine 1-phosphate signaling pathway in a mouse model of diethylnitrosamine-induced hepatocellular carcinoma.Evaluation of Consistency in Spheroid Invasion Assays.SKI-178: A Multitargeted Inhibitor of Sphingosine Kinase and Microtubule Dynamics Demonstrating Therapeutic Efficacy in Acute Myeloid Leukemia Models.Lipophagy prevents activity-dependent neurodegeneration due to dihydroceramide accumulation in vivo.Sphingolipid pathway enzymes modulate cell fate and immune responses.New extracellular factors in glioblastoma multiforme development: neurotensin, growth differentiation factor-15, sphingosine-1-phosphate and cytomegalovirus infection.Typical and Atypical Inducers of Lysosomal Cell Death: A Promising Anticancer Strategy
P2860
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P2860
A sphingosine kinase inhibitor combined with temozolomide induces glioblastoma cell death through accumulation of dihydrosphingosine and dihydroceramide, endoplasmic reticulum stress and autophagy
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
A sphingosine kinase inhibitor ...... reticulum stress and autophagy
@ast
A sphingosine kinase inhibitor ...... reticulum stress and autophagy
@en
type
label
A sphingosine kinase inhibitor ...... reticulum stress and autophagy
@ast
A sphingosine kinase inhibitor ...... reticulum stress and autophagy
@en
prefLabel
A sphingosine kinase inhibitor ...... reticulum stress and autophagy
@ast
A sphingosine kinase inhibitor ...... reticulum stress and autophagy
@en
P2093
P2860
P356
P1476
A sphingosine kinase inhibitor ...... reticulum stress and autophagy
@en
P2093
A Régnier-Vigouroux
P2860
P356
10.1038/CDDIS.2014.384
P577
2014-09-25T00:00:00Z