The proteasome: a proteolytic nanomachine of cell regulation and waste disposal.
about
Suppression of the deubiquitinating enzyme USP5 causes the accumulation of unanchored polyubiquitin and the activation of p53A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons.Studying protein complexes by the yeast two-hybrid systemThe cytoplasmic Hsp70 chaperone machinery subjects misfolded and endoplasmic reticulum import-incompetent proteins to degradation via the ubiquitin-proteasome systemColorectal Carcinogenesis, Radiation Quality, and the Ubiquitin-Proteasome PathwayThe Importance of Ubiquitin E3 Ligases, SCF and APC/C, in Human CancersMisframed ubiquitin and impaired protein quality control: an early event in Alzheimer's diseaseNuclear Import of Yeast ProteasomesThe role of targeted protein degradation in early neural developmentDual functions of the Hsm3 protein in chaperoning and scaffolding regulatory particle subunits during the proteasome assemblyStructure and properties of transcriptional networks driving selenite stress response in yeastsEndoplasmic Reticulum-associated Degradation of Pca1p, a Polytopic Protein, via Interaction with the Proteasome at the MembraneBlm10 protein promotes proteasomal substrate turnover by an active gating mechanismProteasomes can degrade a significant proportion of cellular proteins independent of ubiquitination.FACT and the proteasome promote promoter chromatin disassembly and transcriptional initiation.Cks1, Cdk1, and the 19S proteasome collaborate to regulate gene induction-dependent nucleosome eviction in yeastThe nuclear basket proteins Mlp1p and Mlp2p are part of a dynamic interactome including Esc1p and the proteasome.Degradation of misfolded protein in the cytoplasm is mediated by the ubiquitin ligase Ubr1.Ubiquitination of Lysine 867 of the Human SETDB1 Protein Upregulates Its Histone H3 Lysine 9 (H3K9) Methyltransferase ActivityPathogenesis of colorectal carcinoma and therapeutic implications: the roles of the ubiquitin-proteasome system and Cox-2Aggresome formation and neurodegenerative diseases: therapeutic implicationsRibosomal protein S29 regulates metabolic insecticide resistance through binding and degradation of CYP6N3Misfolding of proteins with a polyglutamine expansion is facilitated by proteasomal chaperonesEDD enhances cell survival and cisplatin resistance and is a therapeutic target for epithelial ovarian cancer.Direct ubiquitin independent recognition and degradation of a folded protein by the eukaryotic proteasomes-origin of intrinsic degradation signals.C. elegans dss-1 is functionally conserved and required for oogenesis and larval growth.Ubiquitination is required for effective replication of coxsackievirus B3.Proteasome subunits mRNA expressions correlate with male BMI: implications for a role in obesity.Inference of sparse combinatorial-control networks from gene-expression data: a message passing approach.Gel-based proteomics analysis of the heterogeneity of 20S proteasomes from four human pancreatic cancer cell lines.The N-end rule pathway and regulation by proteolysisThe ubiquitin-proteasome system: central modifier of plant signalling.Aminoacyl-transferases and the N-end rule pathway of prokaryotic/eukaryotic specificity in a human pathogenMolecular and proteomic analyses highlight the importance of ubiquitination for the stress resistance, metabolic adaptation, morphogenetic regulation and virulence of Candida albicansE3 ubiquitin ligases and plant innate immunity.Global organization and function of mammalian cytosolic proteasome pools: Implications for PA28 and 19S regulatory complexes.Timely activation of budding yeast APCCdh1 involves degradation of its inhibitor, Acm1, by an unconventional proteolytic mechanism.Identification of Novel Proteasome Inhibitors from an Enaminone Library.Characterisation of 20S Proteasome in Tritrichomonas foetus and Its Role during the Cell Cycle and Transformation into Endoflagellar Form.Ubiquitination of newly synthesized proteins at the ribosome.
P2860
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P2860
The proteasome: a proteolytic nanomachine of cell regulation and waste disposal.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
The proteasome: a proteolytic nanomachine of cell regulation and waste disposal.
@ast
The proteasome: a proteolytic nanomachine of cell regulation and waste disposal.
@en
type
label
The proteasome: a proteolytic nanomachine of cell regulation and waste disposal.
@ast
The proteasome: a proteolytic nanomachine of cell regulation and waste disposal.
@en
prefLabel
The proteasome: a proteolytic nanomachine of cell regulation and waste disposal.
@ast
The proteasome: a proteolytic nanomachine of cell regulation and waste disposal.
@en
P1476
The proteasome: a proteolytic nanomachine of cell regulation and waste disposal.
@en
P2093
Dieter H Wolf
Wolfgang Hilt
P356
10.1016/J.BBAMCR.2004.10.007
P407
P577
2004-11-01T00:00:00Z