Elucidation of functions of human cytochrome P450 enzymes: identification of endogenous substrates in tissue extracts using metabolomic and isotopic labeling approaches
about
Characterizing proteins of unknown function: orphan cytochrome p450 enzymes as a paradigm.Hydroxylation of the triterpenoid dipterocarpol with CYP106A2 from Bacillus megaterium.Dansylation of unactivated alcohols for improved mass spectral sensitivity and application to analysis of cytochrome P450 oxidation products in tissue extracts.Metabolomic strategies for the identification of new enzyme functions and metabolic pathwaysTargeting of splice variants of human cytochrome P450 2C8 (CYP2C8) to mitochondria and their role in arachidonic acid metabolism and respiratory dysfunction.Orphans in the human cytochrome P450 superfamily: approaches to discovering functions and relevance in pharmacology.Metabolomic analysis and identification of a role for the orphan human cytochrome P450 2W1 in selective oxidation of lysophospholipidsC. elegans flavin-containing monooxygenase-4 is essential for osmoregulation in hypotonic stressApproaches to deorphanization of human and microbial cytochrome P450 enzymes.Functional proteomics: application of mass spectrometry to the study of enzymology in complex mixtures.Oxidation of endogenous N-arachidonoylserotonin by human cytochrome P450 2U1.The glycerophospho metabolome and its influence on amino acid homeostasis revealed by brain metabolomics of GDE1(-/-) mice.Bioactivation of Aromatic Amines by Human CYP2W1, An Orphan Cytochrome P450 Enzyme.Human cytochrome P450 4F11: heterologous expression in bacteria, purification, and characterization of catalytic function.High-resolution magic-angle-spinning NMR spectroscopy for metabolic profiling of intact tissues.
P2860
Q33953907-B50DDA1E-8A9C-4973-BD74-B7FB69D563EEQ34136071-B364DD59-1821-44B0-A20E-20B3FC2FB645Q34138950-B600BFB1-1336-4D03-932C-5A7AF85623E9Q34342551-5EBA92CD-D042-4955-86C1-3C63A4CA8F90Q34396767-37E5178A-003A-4763-AF4A-1581F66C5646Q35122778-290EF4E1-4425-4F34-B544-08B3D2FEF583Q36520398-FEF50E84-EA5E-4482-A88D-736B09686CF8Q36920811-557CC07F-94DC-4D37-82EE-C251BC3320F6Q37759731-10155A56-2F0A-44B3-BE1F-72BA9F885A50Q37902554-2BC4748D-C2E4-46F9-B2DF-9015502B31ECQ39995855-B638E20E-F20E-4361-90B9-5AED689D4A19Q41825083-5EC26FF9-AD36-4DF6-B74C-D85FDB1ACED9Q42856168-33FBB501-C3F1-4233-AF49-5F35ECCF0617Q42929087-88BD0AB2-19CE-4168-B6CB-B7E1D5B1BA2DQ44330989-5F7DCEBA-D250-4897-A4BD-797D645CAD16
P2860
Elucidation of functions of human cytochrome P450 enzymes: identification of endogenous substrates in tissue extracts using metabolomic and isotopic labeling approaches
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Elucidation of functions of hu ...... d isotopic labeling approaches
@ast
Elucidation of functions of hu ...... d isotopic labeling approaches
@en
type
label
Elucidation of functions of hu ...... d isotopic labeling approaches
@ast
Elucidation of functions of hu ...... d isotopic labeling approaches
@en
prefLabel
Elucidation of functions of hu ...... d isotopic labeling approaches
@ast
Elucidation of functions of hu ...... d isotopic labeling approaches
@en
P2093
P2860
P356
P1433
P1476
Elucidation of functions of hu ...... d isotopic labeling approaches
@en
P2093
F Peter Guengerich
Martha V Martin
Zhongmei Tang
P2860
P304
P356
10.1021/AC900021A
P407
P577
2009-04-01T00:00:00Z