Altered stability of etoposide-induced topoisomerase II-DNA complexes in resistant human leukaemia K562 cells
about
Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemiaA diazirine-based photoaffinity etoposide probe for labeling topoisomerase II.Optimizing antimetabolite-based chemotherapy for the treatment of childhood acute lymphoblastic leukaemia.Mechanisms regulating resistance to inhibitors of topoisomerase II.The anticancer multi-kinase inhibitor dovitinib also targets topoisomerase I and topoisomerase II.Structure-based design, synthesis and biological testing of etoposide analog epipodophyllotoxin-N-mustard hybrid compounds designed to covalently bind to topoisomerase II and DNAMechanism of the cytotoxicity of the diazoparaquinone antitumor antibiotic kinamycin FStructure-based design, synthesis and biological testing of piperazine-linked bis-epipodophyllotoxin etoposide analogsMechanisms of resistance to combinations of vincristine, etoposide and doxorubicin in Chinese hamster ovary cells.Effect of transfection of a Drosophila topoisomerase II gene into a human brain tumour cell line intrinsically resistant to etoposide.Mechanisms of Action and Reduced Cardiotoxicity of Pixantrone; a Topoisomerase II Targeting Agent with Cellular Selectivity for the Topoisomerase IIα Isoform.The structure-based design, synthesis and biological evaluation of DNA-binding bisintercalating bisanthrapyrazole anticancer compounds.Design, synthesis, and biological evaluation of a novel series of bisintercalating DNA-binding piperazine-linked bisanthrapyrazole compounds as anticancer agents.The anticancer thiosemicarbazones Dp44mT and triapine lack inhibitory effects as catalytic inhibitors or poisons of DNA topoisomerase IIα.Design, synthesis and biological evaluation of a novel series of anthrapyrazoles linked with netropsin-like oligopyrrole carboxamides as anticancer agentsAltered drug sensitivity in response to idarubicin treatment in K562 human leukaemia cells.Reduction of etoposide induced cell killing by hyperthermia can occur without changes in etoposide transport or DNA topoisomerase II activity.Attenuation of drug-stimulated topoisomerase II-DNA cleavable complex formation in wild-type HL-60 cells treated with an intracellular calcium buffer is correlated with decreased cytotoxicity and site-specific hypophosphorylation of topoisomerase IICadmium is a catalytic inhibitor of DNA topoisomerase II.Structure-activity study of the interaction of bioreductive benzoquinone alkylating agents with DNA topoisomerase II.Alternative RNA Processing of Topoisomerase IIα in Etoposide-Resistant Human Leukemia K562 Cells: Intron Retention Results in a Novel C-Terminal Truncated 90-kDa Isoform.Synthesis and antiproliferative activity of derivatives of the phyllanthusmin class of arylnaphthalene lignan lactones.
P2860
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P2860
Altered stability of etoposide-induced topoisomerase II-DNA complexes in resistant human leukaemia K562 cells
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Altered stability of etoposide ...... ant human leukaemia K562 cells
@ast
Altered stability of etoposide ...... ant human leukaemia K562 cells
@en
type
label
Altered stability of etoposide ...... ant human leukaemia K562 cells
@ast
Altered stability of etoposide ...... ant human leukaemia K562 cells
@en
prefLabel
Altered stability of etoposide ...... ant human leukaemia K562 cells
@ast
Altered stability of etoposide ...... ant human leukaemia K562 cells
@en
P2093
P2860
P356
P1476
Altered stability of etoposide ...... ant human leukaemia K562 cells
@en
P2093
J C Yalowich
V V Bergoltz
P2860
P2888
P304
P356
10.1038/BJC.1994.131
P407
P577
1994-04-01T00:00:00Z