The anticancer thiosemicarbazones Dp44mT and triapine lack inhibitory effects as catalytic inhibitors or poisons of DNA topoisomerase IIα.
about
The anticancer multi-kinase inhibitor dovitinib also targets topoisomerase I and topoisomerase II.Structure-based design, synthesis and biological testing of etoposide analog epipodophyllotoxin-N-mustard hybrid compounds designed to covalently bind to topoisomerase II and DNAIron chelators with topoisomerase-inhibitory activity and their anticancer applications.The ascidian natural product eusynstyelamide B is a novel topoisomerase II poison that induces DNA damage and growth arrest in prostate and breast cancer cellsSynthesis, molecular modeling, and biological evaluation of novel chiral thiosemicarbazone derivatives as potent anticancer agents.Synthesis and biological evaluation of benzo[a]phenazine derivatives as a dual inhibitor of topoisomerase I and II.The role of oxidative stress in activity of anticancer thiosemicarbazones.
P2860
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P2860
The anticancer thiosemicarbazones Dp44mT and triapine lack inhibitory effects as catalytic inhibitors or poisons of DNA topoisomerase IIα.
description
2012 nî lūn-bûn
@nan
2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
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2012年學術文章
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2012年學術文章
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name
The anticancer thiosemicarbazo ...... sons of DNA topoisomerase IIα.
@en
The anticancer thiosemicarbazo ...... sons of DNA topoisomerase IIα.
@nl
type
label
The anticancer thiosemicarbazo ...... sons of DNA topoisomerase IIα.
@en
The anticancer thiosemicarbazo ...... sons of DNA topoisomerase IIα.
@nl
prefLabel
The anticancer thiosemicarbazo ...... sons of DNA topoisomerase IIα.
@en
The anticancer thiosemicarbazo ...... sons of DNA topoisomerase IIα.
@nl
P2093
P2860
P1476
The anticancer thiosemicarbazo ...... sons of DNA topoisomerase IIα.
@en
P2093
Brian B Hasinoff
Jack C Yalowich
Marisa Hornbaker
Ragu Kanagasabai
P2860
P356
10.1016/J.BCP.2012.03.021
P407
P577
2012-04-04T00:00:00Z