High-throughput screening using the differential radial capillary action of ligand assay identifies ebselen as an inhibitor of diguanylate cyclases.
about
Biofilms and Cyclic di-GMP (c-di-GMP) Signaling: Lessons from Pseudomonas aeruginosa and Other BacteriaQuorum sensing and biofilm formation in mycobacteria: role of c-di-GMP and methods to study this second messengerBacterial Signal Transduction by Cyclic Di-GMP and Other Nucleotide Second MessengersEbselen inhibits hepatitis C virus NS3 helicase binding to nucleic acid and prevents viral replicationControl of Biofilms with the Fatty Acid Signaling Molecule cis-2-Decenoic Acid.The Diguanylate Cyclase HsbD Intersects with the HptB Regulatory Cascade to Control Pseudomonas aeruginosa Biofilm and MotilityEbselen induces reactive oxygen species (ROS)-mediated cytotoxicity in Saccharomyces cerevisiae with inhibition of glutamate dehydrogenase being a target.Strategies for combating bacterial biofilm infections.Considerations and caveats in anti-virulence drug development.Combating chronic bacterial infections by manipulating cyclic nucleotide-regulated biofilm formation.Cyclic dinucleotide (c-di-GMP, c-di-AMP, and cGAMP) signalings have come of age to be inhibited by small molecules.In Silico Discovery and In Vitro Validation of Catechol-Containing Sulfonohydrazide Compounds as Potent Inhibitors of the Diguanylate Cyclase PleDSmall Molecules That Sabotage Bacterial Virulence.Strategies for combating bacterial biofilms: A focus on anti-biofilm agents and their mechanisms of action.Bacterial Biofilm Control by Perturbation of Bacterial Signaling Processes.Discovery of the Second Messenger Cyclic di-GMP.Synergistic antibacterial effect of silver and ebselen against multidrug-resistant Gram-negative bacterial infections.A small-molecule antivirulence agent for treating Clostridium difficile infection.Prospects for Anti-Biofilm Pharmaceuticals.Brucella abortus Triggers a cGAS-Independent STING Pathway To Induce Host Protection That Involves Guanylate-Binding Proteins and Inflammasome Activation.Discovering Selective Diguanylate Cyclase Inhibitors: From PleD to Discrimination of the Active Site of Cyclic-di-GMP Phosphodiesterases.Antimicrobial Photodynamic Therapy to Control Clinically Relevant Biofilm Infections.Inhibition of c-di-GMP phosphodiesterase RocR and swarming motility by a benzoisothiazolinone derivativeExploring the simultaneous σ-hole/π-hole bonding characteristics of a Br⋯π interaction in an ebselen derivative experimental and theoretical electron-density analysis
P2860
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P2860
High-throughput screening using the differential radial capillary action of ligand assay identifies ebselen as an inhibitor of diguanylate cyclases.
description
2013 nî lūn-bûn
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
@zh-hk
2013年論文
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2013年論文
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2013年论文
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2013年论文
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2013年论文
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name
High-throughput screening usin ...... bitor of diguanylate cyclases.
@ast
High-throughput screening usin ...... bitor of diguanylate cyclases.
@en
type
label
High-throughput screening usin ...... bitor of diguanylate cyclases.
@ast
High-throughput screening usin ...... bitor of diguanylate cyclases.
@en
prefLabel
High-throughput screening usin ...... bitor of diguanylate cyclases.
@ast
High-throughput screening usin ...... bitor of diguanylate cyclases.
@en
P2860
P50
P356
P1433
P1476
High-throughput screening usin ...... bitor of diguanylate cyclases.
@en
P2093
Ori J Lieberman
P2860
P304
P356
10.1021/CB400485K
P577
2013-11-04T00:00:00Z