Alpha2-macroglobulin associates with beta-amyloid peptide and prevents fibril formation - Wikidata - awgldk - TriplyDB

Alpha2-macroglobulin associates with beta-amyloid peptide and prevents fibril formation

Alpha2-macroglobulin associates with beta-amyloid peptide and prevents fibril formation

http://www.wikidata.org/entity/Q35985986

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Protease-activated alpha-2-macroglobulin can inhibit amyloid formation via two distinct mechanisms Interactome mapping suggests new mechanistic details underlying Alzheimer's disease Role of ROS and RNS Sources in Physiological and Pathological Conditions The low-density lipoprotein receptor-related protein 1 and amyloid-β clearance in Alzheimer's disease Structure of a rat α1-macroglobulin receptor-binding domain dimer Inflammation and Alzheimer's disease A mathematical model of the kinetics of beta-amyloid fibril growth from the denatured state Increased β-amyloid deposition in Tg-SWDI transgenic mouse brain following in vivo lead exposure The catalytic domain of insulin-degrading enzyme forms a denaturant-resistant complex with amyloid beta peptide: implications for Alzheimer disease pathogenesis The low density lipoprotein receptor gene family. Differential expression of two alpha2-macroglobulin receptors in the brain Identification and validation of novel cerebrospinal fluid biomarkers for staging early Alzheimer's disease Distinct binding sites in the structure of alpha 2-macroglobulin mediate the interaction with beta-amyloid peptide and growth factors.Characterizing Aging, Mild Cognitive Impairment, and Dementia with Blood-Based Biomarkers and Neuropsychology.Cholesterol is an important factor affecting the membrane insertion of beta-amyloid peptide (A beta 1-40), which may potentially inhibit the fibril formation.Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set.Amyloid oligomer conformation in a group of natively folded proteins.Genetic risk factors in Alzheimer's disease Hypochlorite-induced structural modifications enhance the chaperone activity of human α2-macroglobulin.Extracellular chaperones modulate the effects of Alzheimer's patient cerebrospinal fluid on Abeta(1-42) toxicity and uptake Confounding factors influencing amyloid Beta concentration in cerebrospinal fluid Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein Expression of Panza, an alpha2-macroglobulin, in a restricted dorsal domain of the primitive gut in Xenopus laevis.More than cholesterol transporters: lipoprotein receptors in CNS function and neurodegeneration The irreversible binding of amyloid peptide substrates to insulin-degrading enzyme: a biological perspective Physiopathological modulators of amyloid aggregation and novel pharmacological approaches in Alzheimer's disease.Meta-analyses of 8 polymorphisms associated with the risk of the Alzheimer's disease.Alpha-2-Macroglobulin Is Acutely Sensitive to Freezing and Lyophilization: Implications for Structural and Functional Studies.Astroglial expression of human alpha(1)-antichymotrypsin enhances alzheimer-like pathology in amyloid protein precursor transgenic mice.Amyloid accomplices and enforcers Hsp20, a novel alpha-crystallin, prevents Abeta fibril formation and toxicity.A shift in microglial β-amyloid binding in Alzheimer's disease is associated with cerebral amyloid angiopathy.Assessing candidate serum biomarkers for Alzheimer's disease: a longitudinal study.Heat shock proteins and amateur chaperones in amyloid-Beta accumulation and clearance in Alzheimer's disease.Potential roles of abundant extracellular chaperones in the control of amyloid formation and toxicity.Genetics of Alzheimer's disease in Caribbean Hispanic and African American populations.Influence of Alpha-2-Macroglobulin 5 bp I/D and Ile1000Val polymorphisms on the susceptibility of Alzheimer's disease: a systematic review and meta-analysis of 52 studies.Impact of Cytokines and Chemokines on Alzheimer's Disease Neuropathological Hallmarks.Characterization of a novel positive transcription regulatory element that differentially regulates the alpha-2-macroglobulin gene in replicative senescence.Conformation dependent pro-apoptotic activity of the recombinant human prion protein fragment 90-231.Cardiovascular dementia - a different perspective.

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P2860

Alpha2-macroglobulin associates with beta-amyloid peptide and prevents fibril formation

http://www.wikidata.org/entity/Q35985986

description

1998 nî lūn-bûn

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1998年の論文

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1998年論文

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1998年論文

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1998年論文

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1998年论文

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1998年论文

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1998年论文

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name

Alpha2-macroglobulin associates with beta-amyloid peptide and prevents fibril formation

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Alpha2-macroglobulin associates with beta-amyloid peptide and prevents fibril formation

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type

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Alpha2-macroglobulin associates with beta-amyloid peptide and prevents fibril formation

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Alpha2-macroglobulin associates with beta-amyloid peptide and prevents fibril formation

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prefLabel

Alpha2-macroglobulin associates with beta-amyloid peptide and prevents fibril formation

@ast

Alpha2-macroglobulin associates with beta-amyloid peptide and prevents fibril formation

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Alpha2-macroglobulin associates with beta-amyloid peptide and prevents fibril formation

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P2093

J Heroux

http://www.w3.org/2001/XMLSchema#string

J Knaeblein

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N G Riedel

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O Khorkova

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S Goyal

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S R Hughes

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S Sahasrabudhe

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P2860

Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2

Amyloid plaque core protein in Alzheimer disease and Down syndrome

Primary structure of human alpha 2-macroglobulin. V. The complete structure

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

Differences between vascular and plaque core amyloid in Alzheimer's disease.

A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor.

Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids.

Alpha 2-macroglobulin, a multifunctional binding protein with targeting characteristics.

Nucleotide sequence of cDNA encoding human alpha 2-macroglobulin and assignment of the chromosomal locus.

Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells

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3275-3280

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6

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235617379

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9501253

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19732

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