Conformation dependent pro-apoptotic activity of the recombinant human prion protein fragment 90-231.
about
Investigation of the molecular similarity in closely related protein systems: The PrP case study.Immunopurification of pathological prion protein aggregatesCalcium binding promotes prion protein fragment 90-231 conformational change toward a membrane destabilizing and cytotoxic structure.Human PrP90-231-induced cell death is associated with intracellular accumulation of insoluble and protease-resistant macroaggregates and lysosomal dysfunction.Role of prion protein aggregation in neurotoxicity.Cellular prion protein controls stem cell-like properties of human glioblastoma tumor-initiating cellsDifferent Molecular Mechanisms Mediate Direct or Glia-Dependent Prion Protein Fragment 90-231 Neurotoxic Effects in Cerebellar Granule Neurons.Excitotoxicity through NMDA receptors mediates cerebellar granule neuron apoptosis induced by prion protein 90-231 fragment.Pharmacological activation of autophagy favors the clearing of intracellular aggregates of misfolded prion protein peptide to prevent neuronal death.
P2860
Q30375050-EC14DA47-F4DA-41E9-BB4F-303FB42CBFD8Q33516017-F226EFB3-7B53-480F-8D29-3047579A95A3Q34343507-7D0EEB9B-9B1F-44D6-980C-ED34E7E4F1F0Q35006421-4B42D537-9313-4B91-8D6C-41F6389A39EDQ36197275-A706C4C1-324F-4A85-A746-703664AAF8DFQ37437614-8BC9BEED-A058-4A8B-BCB5-66C52120D2BCQ38765903-0C331225-B6E7-47A3-B64F-A0E03A5DFC9AQ48421263-A8BA5D86-D1AA-4421-B8F3-98B801091EB0Q48507581-230E9E1C-FDF8-4964-9DDF-277A964D107C
P2860
Conformation dependent pro-apoptotic activity of the recombinant human prion protein fragment 90-231.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Conformation dependent pro-apo ...... prion protein fragment 90-231.
@en
type
label
Conformation dependent pro-apo ...... prion protein fragment 90-231.
@en
prefLabel
Conformation dependent pro-apo ...... prion protein fragment 90-231.
@en
P2093
P2860
P1476
Conformation dependent pro-apo ...... prion protein fragment 90-231
@en
P2093
G Schettini
K Chiovitti
P Ballerini
P2860
P304
P356
10.1177/039463200601900211
P577
2006-04-01T00:00:00Z