FGF21 is increased by inflammatory stimuli and protects leptin-deficient ob/ob mice from the toxicity of sepsis - Wikidata - awgldk - TriplyDB

FGF21 is increased by inflammatory stimuli and protects leptin-deficient ob/ob mice from the toxicity of sepsis

FGF21 is increased by inflammatory stimuli and protects leptin-deficient ob/ob mice from the toxicity of sepsis

http://www.wikidata.org/entity/Q35986135

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Research Perspectives on the Regulation and Physiological Functions of FGF21 and its Association with NAFLD FGF-21, a novel metabolic regulator, has a robust neuroprotective role and is markedly elevated in neurons by mood stabilizers Fibroblast Growth Factor 21 Deficiency Attenuates Experimental Colitis-Induced Adipose Tissue Lipolysis Potent long-acting rhFGF21 analog for treatment of diabetic nephropathy in db/db and DIO mice Attenuation of hyperlipidemia- and diabetes-induced early-stage apoptosis and late-stage renal dysfunction via administration of fibroblast growth factor-21 is associated with suppression of renal inflammation Molecular characterization and mapping of Fgf21 gene in a foodfish species asian seabass.Role of fibroblast growth factor 21 in the early stage of NASH induced by methionine- and choline-deficient diet Fibroblast growth factor 21 prevents atherosclerosis by suppression of hepatic sterol regulatory element-binding protein-2 and induction of adiponectin in mice.Alterations in Hepatic FGF21, Co-Regulated Genes, and Upstream Metabolic Genes in Response to Nutrition, Ketosis and Inflammation in Peripartal Holstein Cows.Forced expression of fibroblast growth factor 21 reverses the sustained impairment of liver regeneration in hPPARα(PAC) mice due to dysregulated bile acid synthesis Elevated Serum Fibroblast Growth Factor 21 in Humans with Acute Pancreatitis.Fibroblast growth factor 21 deficiency exacerbates chronic alcohol-induced hepatic steatosis and injury Endocrine protection of ischemic myocardium by FGF21 from the liver and adipose tissue.Valproic Acid and Other HDAC Inhibitors Upregulate FGF21 Gene Expression and Promote Process Elongation in Glia by Inhibiting HDAC2 and 3 The Role of Clinical Proteomics, Lipidomics, and Genomics in the Diagnosis of Alzheimer's Disease.Gene expression profiling in subcutaneous, visceral and epigastric adipose tissues of patients with extreme obesity The emerging role of fibroblast growth factor 21 in diabetic nephropathy.Pancreatic Islet Responses to Metabolic Trauma.Enteroendocrine cells-sensory sentinels of the intestinal environment and orchestrators of mucosal immunity.Nutrition, infection and stunting: the roles of deficiencies of individual nutrients and foods, and of inflammation, as determinants of reduced linear growth of children.Opposing Effects of Fasting Metabolism on Tissue Tolerance in Bacterial and Viral Inflammation Cardioprotective effects of fibroblast growth factor 21 against doxorubicin-induced toxicity via the SIRT1/LKB1/AMPK pathway.Lack of fibroblast growth factor 21 accelerates metabolic liver injury characterized by steatohepatities in mice.LPS infusion suppresses serum FGF21 levels in healthy adult volunteers A new link between innate immunity and hepatic metabolism: attractive unknown place to visit Increased FGF21 plasma levels in humans with sepsis and SIRS.Fibroblast growth factor (FGF21) protects mouse liver against D-galactose-induced oxidative stress and apoptosis via activating Nrf2 and PI3K/Akt pathways.A novel function for fibroblast growth factor 21: stimulation of NADPH oxidase-dependent ROS generation.Fibroblast growth factor 21 protects against acetaminophen-induced hepatotoxicity by potentiating peroxisome proliferator-activated receptor coactivator protein-1α-mediated antioxidant capacity in mice.FGF-21 Plays a Crucial Role in the Glucose Uptake of Activated Monocytes.Anti-inflammatory effects of exercise training in adipose tissue do not require FGF21.Expression of Fibroblast Growth Factor 21 and β-Klotho Regulates Hepatic Fibrosis through the Nuclear Factor-κB and c-Jun N-Terminal Kinase Pathways.Fibroblast growth factor 21 protects the heart from apoptosis in a diabetic mouse model via extracellular signal-regulated kinase 1/2-dependent signalling pathway.Possible role of fibroblast growth factor 21 on atherosclerosis via amelioration of endoplasmic reticulum stress-mediated apoptosis in apoE(-/-) mice.Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemia A study of the circulating fibroblast growth factor 21 as a novel noninvasive biomarker of hepatic injury in genotype-4 chronic hepatitis C: Egyptian patients and their response to direct-acting antiviral agents

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FGF21 is increased by inflammatory stimuli and protects leptin-deficient ob/ob mice from the toxicity of sepsis

http://www.wikidata.org/entity/Q35986135

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2012 nî lūn-bûn

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2012年论文

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2012年论文

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name

FGF21 is increased by inflamma ...... ce from the toxicity of sepsis

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FGF21 is increased by inflamma ...... ce from the toxicity of sepsis

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FGF21 is increased by inflamma ...... ce from the toxicity of sepsis

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FGF21 is increased by inflamma ...... ce from the toxicity of sepsis

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FGF21 is increased by inflamma ...... ce from the toxicity of sepsis

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FGF21 is increased by inflamma ...... ce from the toxicity of sepsis

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FGF21 is increased by inflamma ...... ce from the toxicity of sepsis

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Akanksha Gupta

http://www.w3.org/2001/XMLSchema#string

Alexei Kharitonenkov

http://www.w3.org/2001/XMLSchema#string

Arthur Moser

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Carl Grunfeld

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Holly Bina

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Josef G Heuer

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Judy K Shigenaga

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Kenneth R Feingold

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Martin Cramer

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Sophie M Patzek

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P2860

Identification of a novel FGF, FGF-21, preferentially expressed in the liver

FGF-21 as a novel metabolic regulator.

Mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase: a control enzyme in ketogenesis

FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

Fibroblast growth factor 21: from pharmacology to physiology

Acute-phase proteins and other systemic responses to inflammation

Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states

Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21

The metabolic state of diabetic monkeys is regulated by fibroblast growth factor-21.

Circulating FGF-21 levels in normal subjects and in newly diagnose patients with Type 2 diabetes mellitus.

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2689-2700

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10.1210/EN.2011-1496

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6

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153

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2012-04-02T00:00:00Z

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223986645

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22474187

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3359613

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