Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemia - Wikidata - awgldk - TriplyDB

Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemia

Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemia

http://www.wikidata.org/entity/Q57636621

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Role of adipose tissue in methionine-choline-deficient model of non-alcoholic steatohepatitis (NASH)Fructo-oligosaccharides and intestinal barrier function in a methionine-choline-deficient mouse model of nonalcoholic steatohepatitis.Fatty acid elongase-5 (Elovl5) regulates hepatic triglyceride catabolism in obese C57BL/6J mice Role of white adipose lipolysis in the development of NASH induced by methionine- and choline-deficient diet.High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice.Fatty acid signaling: the new function of intracellular lipases.Adipose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of hepatic stellate cells.Impact of Reduced ATGL-Mediated Adipocyte Lipolysis on Obesity-Associated Insulin Resistance and Inflammation in Male Mice.Regulation of Lipolysis and Adipose Tissue Signaling during Acute Endotoxin-Induced Inflammation: A Human Randomized Crossover Trial.Fibroblast growth factor 21 is induced upon cardiac stress and alters cardiac lipid homeostasis.Regulation of Hepatic Triacylglycerol Metabolism by CGI-58 Does Not Require ATGL Co-activation.Hepatocyte specific expression of an oncogenic variant of β-catenin results in cholestatic liver disease Inhibition of age-related cytokines production by ATGL: a mechanism linked to the anti-inflammatory effect of resveratrol.Selective peroxisome proliferator-activated receptor-α modulator K-877 efficiently activates the peroxisome proliferator-activated receptor-α pathway and improves lipid metabolism in mice.Distinct but complementary contributions of PPAR isotypes to energy homeostasis.G0S2: A small giant controller of lipolysis and adipose-liver fatty acid flux.CD18 deficiency improves liver injury in the MCD model of steatohepatitis.Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism.Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD.Disturbed Vitamin A Metabolism in Non-Alcoholic Fatty Liver Disease (NAFLD).Dendrobium nobile Lindl. alkaloids regulate metabolism gene expression in livers of mice.Critical roles for α/β hydrolase domain 5 (ABHD5)/comparative gene identification-58 (CGI-58) at the lipid droplet interface and beyond.Hints on ATGL implications in cancer: beyond bioenergetic clues.Targeting Hepatic Glycerolipid Synthesis and Turnover to Treat Fatty Liver Disease

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Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemia

http://www.wikidata.org/entity/Q57636621

description

article

@en

im Januar 2014 veröffentlichter wissenschaftlicher Artikel

@de

wetenschappelijk artikel

@nl

наукова стаття, опублікована в січні 2014

@uk

name

Role of adipose triglyceride l ...... teatohepatitis and endotoxemia

@en

Role of adipose triglyceride lipase

@nl

type

label

Role of adipose triglyceride l ...... teatohepatitis and endotoxemia

@en

Role of adipose triglyceride lipase

@nl

prefLabel

Role of adipose triglyceride l ...... teatohepatitis and endotoxemia

@en

Role of adipose triglyceride lipase

@nl

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Role of adipose triglyceride l ...... teatohepatitis and endotoxemia

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Anna Baghdasaryan

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Emina Halilbasic

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Michael Trauner

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Michaela Mueller

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Thierry Claudel

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P2860

Fatty acids and hypolipidemic drugs regulate peroxisome proliferator-activated receptors alpha - and gamma-mediated gene expression via liver fatty acid binding protein: a signaling path to the nucleus

The mechanisms of action of PPARs

Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis

Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states

Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease.

Human very low density lipoproteins and chylomicrons can protect against endotoxin-induced death in mice

Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning

Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase.

The gene encoding adipose triglyceride lipase (PNPLA2) is mutated in neutral lipid storage disease with myopathy.

Lack of PPARα exacerbates lipopolysaccharide-induced liver toxicity through STAT1 inflammatory signaling and increased oxidative/nitrosative stress

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858-869

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scholarly article

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10.1002/HEP.26732

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3

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59

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Robert Zimmermann

Suman Kumar Das

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2014-01-28T00:00:00Z

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24002947

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