Over-expression of Thioredoxin-1 mediates growth, survival, and chemoresistance and is a druggable target in diffuse large B-cell lymphoma.
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Redox Control of Multidrug Resistance and Its Possible Modulation by AntioxidantsThe Tumorigenic Roles of the Cellular REDOX Regulatory SystemsCross Talk between Two Antioxidant Systems, Thioredoxin and DJ-1: Consequences for CancerNew insights into redox homeostasis as a therapeutic target in B-cell malignancies.Metadherin interference inhibits proliferation and enhances chemo-sensitivity to doxorubicin in diffuse large B cell lymphoma.Growth hormone alters the glutathione S-transferase and mitochondrial thioredoxin systems in long-living Ames dwarf mice.MicroRNA and gene networks in human diffuse large B-cell lymphomaPX-12 inhibits the growth of hepatocelluar carcinoma by inducing S-phase arrest, ROS-dependent apoptosis and enhances 5-FU cytotoxicity.Stromal cell-mediated mitochondrial redox adaptation regulates drug resistance in childhood acute lymphoblastic leukemia.Dimeric peroxiredoxins are druggable targets in human Burkitt lymphoma.PX-12-induced HeLa cell death is associated with oxidative stress and GSH depletion.TrxR1 inhibition overcomes both hypoxia-induced and acquired bortezomib resistance in multiple myeloma through NF-кβ inhibition.Inhibition of thioredoxin 1 leads to apoptosis in drug-resistant multiple myelomaReactive oxygen species, glutathione, and thioredoxin influence suberoyl bishydroxamic acid-induced apoptosis in A549 lung cancer cells.PX-12 induces apoptosis in Calu-6 cells in an oxidative stress-dependent manner.FOXO1 is a TXN- and p300-dependent sensor and effector of oxidative stress in diffuse large B-cell lymphomas characterized by increased oxidative metabolism.Anti-oxidative stress response genes: bioinformatic analysis of their expression and relevance in multiple cancers.The Multifaceted Roles of DJ-1 as an Antioxidant.Suberoylanilide hydroxamic acid induces thioredoxin1-mediated apoptosis in lung cancer cells via up-regulation of miR-129-5p.Expression of thioredoxin-1 (TXN) and its relation with oxidative DNA damage and treatment outcome in adult AML and ALL: A comparative study.Redox-Inactive Peptide Disrupting Trx1-Ask1 Interaction for Selective Activation of Stress Signaling.Interplay between Trx-1 and S100P promotes colorectal cancer cell epithelial-mesenchymal transition by up-regulating S100A4 through AKT activation.The Role of Redox-Regulating Enzymes in Inoperable Breast Cancers Treated with Neoadjuvant Chemotherapy.Proteomics-based investigation of multiple stages of OSCC development indicates that the inhibition of Trx-1 delays oral malignant transformation.High intensity of cytoplasmic peroxiredoxin VI expression is associated with adverse outcome in diffuse large B-cell lymphoma independently of International Prognostic Index.Thioredoxin-1, chemokine (C-X-C motif) ligand-9 and interferon-γ expression in the neoplastic cells and macrophages of Hodgkin lymphoma: clinicopathologic correlations and potential prognostic implications.Macrophages in T cell/histiocyte rich large B cell lymphoma strongly express metal-binding proteins and show a bi-activated phenotype.Upregulation of connexin43 contributes to PX-12-induced oxidative cell death.Expression of genes and proteins of multidrug resistance in gastric cancer cells treated with resveratrol.Clinically relevant inflammatory breast cancer patient-derived xenograft-derived ex vivo model for evaluation of tumor-specific therapies.
P2860
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P2860
Over-expression of Thioredoxin-1 mediates growth, survival, and chemoresistance and is a druggable target in diffuse large B-cell lymphoma.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Over-expression of Thioredoxin ...... diffuse large B-cell lymphoma.
@ast
Over-expression of Thioredoxin ...... diffuse large B-cell lymphoma.
@en
type
label
Over-expression of Thioredoxin ...... diffuse large B-cell lymphoma.
@ast
Over-expression of Thioredoxin ...... diffuse large B-cell lymphoma.
@en
prefLabel
Over-expression of Thioredoxin ...... diffuse large B-cell lymphoma.
@ast
Over-expression of Thioredoxin ...... diffuse large B-cell lymphoma.
@en
P2093
P2860
P356
P1433
P1476
Over-expression of Thioredoxin ...... diffuse large B-cell lymphoma.
@en
P2093
Archito T Tamayo
Changping Li
Francisco Vega
Lan V Pham
Michael A Thompson
Richard J Ford
Zhuang Zuo
P2860
P304
P356
10.18632/ONCOTARGET.463
P407
P577
2012-03-01T00:00:00Z