Chemotherapy triggers HIF-1-dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype.
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Overcoming Hypoxia-Mediated Tumor Progression: Combinatorial Approaches Targeting pH Regulation, Angiogenesis and Immune DysfunctionCell and Signal Components of the Microenvironment of Bone Metastasis Are Affected by HypoxiaA unified model of the hierarchical and stochastic theories of gastric cancer.Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m⁶A-demethylation of NANOG mRNA.HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells.Functional interactions of the cystine/glutamate antiporter, CD44v and MUC1-C oncoprotein in triple-negative breast cancer cells.Collecting duct carcinoma of the kidney is associated with CDKN2A deletion and SLC family gene up-regulation.HIF2α/EFEMP1 cascade mediates hypoxic effects on breast cancer stem cell hierarchy.Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells.Resistance to Cell Death and Its Modulation in Cancer Stem Cells.Differential pattern of HIF-1α expression in HNSCC cancer stem cells after carbon ion or photon irradiation: one molecular explanation of the oxygen effect.Amino Acid Profiling of Zinc Resistant Prostate Cancer Cell Lines: Associations With Cancer Progression.Hypoxia-inducible proteins HIF1α and lactate dehydrogenase LDH5, key markers of anaerobic metabolism, relate with stem cell markers and poor post-radiotherapy outcome in bladder cancer.Remodelling of microRNAs in colorectal cancer by hypoxia alters metabolism profiles and 5-fluorouracil resistance.Hypoxia-inducible factors: coupling glucose metabolism and redox regulation with induction of the breast cancer stem cell phenotype.Systems biology of oxygen homeostasis.Maintenance of redox homeostasis by hypoxia-inducible factors.New Challenges to Study Heterogeneity in Cancer Redox Metabolism.Low hypoxia inducible factor-1α (HIF-1α) expression in testicular germ cell tumors - a major reason for enhanced chemosensitivity?Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine.Restoring microenvironmental redox and pH homeostasis inhibits neoplastic cell growth and migration: therapeutic efficacy of esomeprazole plus sulfasalazine on 3-MCA-induced sarcoma.Engineered Breast Cancer Cell Spheroids Reproduce Biologic Properties of Solid Tumors.Oxidative Stress Promotes Doxorubicin-Induced Pgp and BCRP Expression in Colon Cancer Cells Under Hypoxic Conditions.Multi-omics integration reveals the landscape of pro-metastasis metabolism in hepatocellular carcinoma.Chemotherapy induces enrichment of CD47+/CD73+/PDL1+ immune evasive triple-negative breast cancer cells.Sulfasalazine, an inhibitor of the cystine-glutamate antiporter, reduces DNA damage repair and enhances radiosensitivity in murine B16F10 melanoma.A Virus-Like-Particle immunotherapy targeting Epitope-Specific anti-xCT expressed on cancer stem cell inhibits the progression of metastatic cancer in vivo.A Radiosensitizing Inhibitor of HIF-1 alters the Optical Redox State of Human Lung Cancer Cells In Vitro.A splice junction-targeted CRISPR approach (spJCRISPR) reveals human FOXO3B to be a protein-coding geneBeyond the Warburg Effect: How Do Cancer Cells Regulate One-Carbon Metabolism?
P2860
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P2860
Chemotherapy triggers HIF-1-dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Chemotherapy triggers HIF-1-de ...... st cancer stem cell phenotype.
@ast
Chemotherapy triggers HIF-1-de ...... st cancer stem cell phenotype.
@en
type
label
Chemotherapy triggers HIF-1-de ...... st cancer stem cell phenotype.
@ast
Chemotherapy triggers HIF-1-de ...... st cancer stem cell phenotype.
@en
prefLabel
Chemotherapy triggers HIF-1-de ...... st cancer stem cell phenotype.
@ast
Chemotherapy triggers HIF-1-de ...... st cancer stem cell phenotype.
@en
P2093
P2860
P356
P1476
Chemotherapy triggers HIF-1-de ...... st cancer stem cell phenotype.
@en
P2093
Debangshu Samanta
Haiquan Lu
Hongxia Hu
Huimin Zhang
John W Bullen
Lisha Xiang
P2860
P304
P356
10.1073/PNAS.1513433112
P407
P577
2015-07-30T00:00:00Z