Functional IRF3 deficiency in a patient with herpes simplex encephalitis. - Wikidata - awgldk - TriplyDB

Functional IRF3 deficiency in a patient with herpes simplex encephalitis.

Functional IRF3 deficiency in a patient with herpes simplex encephalitis.

http://www.wikidata.org/entity/Q35992221

about

Type I interferonopathies in pediatric rheumatology Severe infectious diseases of childhood as monogenic inborn errors of immunity Inborn errors underlying herpes simplex encephalitis: From TLR3 to IRF3.Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins.Exome Sequencing Reveals Primary Immunodeficiencies in Children with Community-Acquired Pseudomonas aeruginosa Sepsis.--LUBAC deficiency perturbs TLR3 signaling to cause immunodeficiency and autoinflammation.Dendritic cells, macrophages, NK and CD8+ T lymphocytes play pivotal roles in controlling HSV-1 in the trigeminal ganglia by producing IL1-beta, iNOS and granzyme B.Human Genetic Determinants of Viral Diseases.Inborn errors in RNA polymerase III underlie severe varicella zoster virus infections.Antiviral innate immunity through the lens of systems biology.Herpes Simplex Virus-1 Encephalitis in Adults: Pathophysiology, Diagnosis, and Management.Human TBK1: A Gatekeeper of Neuroinflammation Herpes Simplex Encephalitis: an Update.30 Years of NF-κB: A Blossoming of Relevance to Human Pathobiology.Type I interferon pathway in CNS homeostasis and neurological disorders.Protective and Pathological Immunity during Central Nervous System Infections.Neuronal IFN signaling is dispensable for the establishment of HSV-1 latency.RIG-I is a key antiviral interferon-stimulated gene against hepatitis E virus regardless of interferon production.Mutations in the TLR3 signaling pathway and beyond in adult patients with herpes simplex encephalitis.Sensing of HSV-1 by the cGAS-STING pathway in microglia orchestrates antiviral defence in the CNS.HSV-1 ICP27 targets the TBK1-activated STING signalsome to inhibit virus-induced type I IFN expression Frequently used bioinformatics tools overestimate the damaging effect of allelic variants.Defective RNA sensing by RIG-I in severe influenza virus infection.Inborn Errors of RNA Lariat Metabolism in Humans with Brainstem Viral Infection.IRF4 haploinsufficiency in a family with Whipple's disease.

P2860

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P2860

Functional IRF3 deficiency in a patient with herpes simplex encephalitis.

http://www.wikidata.org/entity/Q35992221

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

@wuu

2015年论文

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2015年论文

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name

Functional IRF3 deficiency in a patient with herpes simplex encephalitis.

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Functional IRF3 deficiency in a patient with herpes simplex encephalitis.

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type

label

Functional IRF3 deficiency in a patient with herpes simplex encephalitis.

@ast

Functional IRF3 deficiency in a patient with herpes simplex encephalitis.

@en

prefLabel

Functional IRF3 deficiency in a patient with herpes simplex encephalitis.

@ast

Functional IRF3 deficiency in a patient with herpes simplex encephalitis.

@en

P1433

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P1433

Journal of Experimental Medicine

P1476

Functional IRF3 deficiency in a patient with herpes simplex encephalitis

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P2093

Emil Kofod-Olsen

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Klara Höning

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Line Lykke Andersen

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Nanna Mørk

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Ryo Narita

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Søren R Paludan

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Takashi Fujita

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Torben F Ørntoft

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Trine H Mogensen

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P2860

Gene expression and antiviral activity of alpha/beta interferons and interleukin-29 in virus-infected human myeloid dendritic cells

Data, information, knowledge and principle: back to metabolism in KEGG

Pathogen recognition and inflammatory signaling in innate immune defenses

Ser386 phosphorylation of transcription factor IRF-3 induces dimerization and association with CBP/p300 without overall conformational change

Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation

IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors

Herpes simplex virus encephalitis in human UNC-93B deficiency

Interferon regulatory factor 3-dependent pathways are critical for control of herpes simplex virus type 1 central nervous system infection.

Human TRAF3 adaptor molecule deficiency leads to impaired Toll-like receptor 3 response and susceptibility to herpes simplex encephalitis.

Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP.

P304

1371-1379

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scholarly article

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10.1084/JEM.20142274

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P433

9

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P478

212

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Jacob Giehm Mikkelsen

Hans Henrik Gad

Lars Østergaard

Mette Christiansen

Kristian A Skipper

Sofie E Jørgensen

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2015-07-27T00:00:00Z

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280536572

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26216125

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4548062

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