PTEN loss defines a TGF-β-induced tubule phenotype of failed differentiation and JNK signaling during renal fibrosis. - Wikidata - awgldk - TriplyDB

PTEN loss defines a TGF-β-induced tubule phenotype of failed differentiation and JNK signaling during renal fibrosis.

PTEN loss defines a TGF-β-induced tubule phenotype of failed differentiation and JNK signaling during renal fibrosis.

http://www.wikidata.org/entity/Q35994534

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Reciprocal regulation of TGF-β and reactive oxygen species: A perverse cycle for fibrosis A proteomics approach to identifying key protein targets involved in VEGF inhibitor mediated attenuation of bleomycin-induced pulmonary fibrosis Severe renal mass reduction impairs recovery and promotes fibrosis after AKI Cellular and Molecular Mechanisms of AKI.MicroRNAs are potential therapeutic targets in fibrosing kidney disease: lessons from animal models.Hyperglycemia, p53, and mitochondrial pathway of apoptosis are involved in the susceptibility of diabetic models to ischemic acute kidney injury.The uremic toxin adsorbent AST-120 abrogates cardiorenal injury following myocardial infarction.Increased expression of p21WAF1/CIP1 in kidney proximal tubules mediates fibrosis.Regulatory Effects and Mechanism of Adenovirus-Mediated PTEN Gene on Hepatic Stellate Cells.Loss of tumour suppressor PTEN expression in renal injury initiates SMAD3- and p53-dependent fibrotic responses Hepatocyte Nuclear Factor-1β Induces Redifferentiation of Dedifferentiated Tubular Epithelial Cells.Simultaneous deletion of Bax and Bak is required to prevent apoptosis and interstitial fibrosis in obstructive nephropathy Mouse model of ischemic acute kidney injury: technical notes and tricks Paracrine Wnt1 Drives Interstitial Fibrosis without Inflammation by Tubulointerstitial Cross-Talk.Conditional Knockout of Src Homology 2 Domain-containing Protein Tyrosine Phosphatase-2 in Myeloid Cells Attenuates Renal Fibrosis after Unilateral Ureter Obstruction.Kidney tubules: intertubular, vascular, and glomerular cross-talk.Persistent activation of autophagy in kidney tubular cells promotes renal interstitial fibrosis during unilateral ureteral obstruction Proximal tubule PPARα attenuates renal fibrosis and inflammation caused by unilateral ureteral obstruction.Suppressed mitochondrial biogenesis in folic acid-induced acute kidney injury and early fibrosis.Hypoxia as a key player in the AKI-to-CKD transition.Failed Tubule Recovery, AKI-CKD Transition, and Kidney Disease Progression.Dysregulation of renal microRNA expression after deep hypothermic circulatory arrest in rats.Extracellular vesicles as immune mediators in response to kidney injury.Mitochondrial Pathology and Glycolytic Shift during Proximal Tubule Atrophy after Ischemic AKI.Pharmacological Inhibition of PTEN Aggravates Acute Kidney Injury.Effects and mechanism of adenovirus-mediated phosphatase and tension homologue deleted on chromosome ten gene on collagen deposition in rat liver fibrosis Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and Gαq-mediated Rho and αvβ6 integrin-dependent activation of TGF-β TGF-β and renal fibrosis: a Pandora's box of surprises.The JNK Signaling Pathway in Renal Fibrosis.Inhibition of PTEN activity aggravates cisplatin-induced acute kidney injury.Integration of Canonical and Noncanonical Pathways in TLR4 Signaling: Complex Regulation of the Wound Repair Program.Experimental Inhibition of Periostin Attenuates Kidney Fibrosis.AKI on CKD: heightened injury, suppressed repair, and the underlying mechanisms.Inpp5e suppresses polycystic kidney disease via inhibition of PI3K/Akt-dependent mTORC1 signaling.Increased progression to kidney fibrosis after erythropoietin is used as a treatment for acute kidney injury.Decreased miR-128 and increased miR-21 synergistically cause podocyte injury in sepsis.Runt-Related Transcription Factor 1 (RUNX1) Promotes TGF-β-Induced Renal Tubular Epithelial-to-Mesenchymal Transition (EMT) and Renal Fibrosis through the PI3K Subunit p110δ.Cancer driver mutations in endometriosis: Variations on the major theme of fibrogenesis

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PTEN loss defines a TGF-β-induced tubule phenotype of failed differentiation and JNK signaling during renal fibrosis.

http://www.wikidata.org/entity/Q35994534

description

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name

PTEN loss defines a TGF-β-indu ...... gnaling during renal fibrosis.

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PTEN loss defines a TGF-β-indu ...... gnaling during renal fibrosis.

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PTEN loss defines a TGF-β-indu ...... gnaling during renal fibrosis.

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PTEN loss defines a TGF-β-indu ...... gnaling during renal fibrosis.

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PTEN loss defines a TGF-β-indu ...... gnaling during renal fibrosis.

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PTEN loss defines a TGF-β-indu ...... gnaling during renal fibrosis.

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AJPRENAL.00660.2011

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American Journal of Physiology - Renal Physiology

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PTEN loss defines a TGF-β-indu ...... gnaling during renal fibrosis.

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Aaron J Polichnowski

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Anil K Bidani

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Donald G McEwen

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Hui Geng

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Joel M Weinberg

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Karen A Griffin

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Manjeri A Venkatachalam

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Pothana Saikumar

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Prajjal K Singha

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Robert Koesters

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P2860

Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta-induced transcription

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

Smads bind directly to the Jun family of AP-1 transcription factors

Coexpression of keratin and vimentin in damaged and regenerating tubular epithelia of the kidney

Essential role for nuclear PTEN in maintaining chromosomal integrity

c-Jun NH2-terminal kinase is crucially involved in renal tubulo-interstitial inflammation

Inhibition of autoregulated TGFbeta signaling simultaneously enhances proliferation and differentiation of kidney epithelium and promotes repair following renal ischemia.

A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis

A novel wounding device suitable for quantitative biochemical analysis of wound healing and regeneration of cultured epithelium.

Acute kidney injury: a springboard for progression in chronic kidney disease

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10.1152/AJPRENAL.00660.2011

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9

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2012-02-01T00:00:00Z

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