Concomitant inactivation of Rb and E2f8 in hematopoietic stem cells synergizes to induce severe anemia
about
Transcriptional control of stem cell fate by E2Fs and pocket proteinsRepression by RB1 characterizes genes involved in the penultimate stage of erythroid developmentE2F activators signal and maintain centrosome amplification in breast cancer cells.Inactivation of Rb and E2f8 synergizes to trigger stressed DNA replication during erythroid terminal differentiation.Characterization of ENU-induced Mutations in Red Blood Cell Structural Proteins.Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality.Involvement of atypical transcription factor E2F8 in the polyploidization during mouse and human decidualization.Silencing of E2F3 suppresses tumor growth of Her2+ breast cancer cells by restricting mitosisMx1-cre mediated Rgs12 conditional knockout mice exhibit increased bone mass phenotype.HIF proteins connect the RB-E2F factors to angiogenesis.Molecular pathways of early CD105-positive erythroid cells as compared with CD34-positive common precursor cells by flow cytometric cell-sorting and gene expression profiling.
P2860
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P2860
Concomitant inactivation of Rb and E2f8 in hematopoietic stem cells synergizes to induce severe anemia
description
2012 nî lūn-bûn
@nan
2012年の論文
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2012年論文
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2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
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2012年論文
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2012年论文
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2012年论文
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2012年论文
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name
Concomitant inactivation of Rb ...... rgizes to induce severe anemia
@ast
Concomitant inactivation of Rb ...... rgizes to induce severe anemia
@en
type
label
Concomitant inactivation of Rb ...... rgizes to induce severe anemia
@ast
Concomitant inactivation of Rb ...... rgizes to induce severe anemia
@en
prefLabel
Concomitant inactivation of Rb ...... rgizes to induce severe anemia
@ast
Concomitant inactivation of Rb ...... rgizes to induce severe anemia
@en
P2093
P2860
P1433
P1476
Concomitant inactivation of Rb ...... rgizes to induce severe anemia
@en
P2093
Charles Wiedmeyer
Seda Ghazaryan
Tinghui Hu
Victor Chang
P2860
P304
P356
10.1182/BLOOD-2011-10-388231
P407
P50
P577
2012-03-14T00:00:00Z