PPARα-UGT axis activation represses intestinal FXR-FGF15 feedback signalling and exacerbates experimental colitis.
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Novel bile acid therapeutics for the treatment of chronic liver diseasesChronic intermittent psychological stress promotes macrophage reverse cholesterol transport by impairing bile acid absorption in mice.Insight into the pharmacokinetic behavior of tanshinone IIA in the treatment of Crohn's disease: comparative data for tanshinone IIA and its two glucuronidated metabolites in normal and recurrent colitis models after oral administration.Reduced total serum bilirubin levels are associated with ulcerative colitisIntestinal transport and metabolism of bile acidsSystematic review: bile acids and intestinal inflammation-luminal aggressors or regulators of mucosal defence?Orally Administered Berberine Modulates Hepatic Lipid Metabolism by Altering Microbial Bile Acid Metabolism and the Intestinal FXR Signaling Pathway.Farnesoid X receptor activation promotes cell proliferation via PDK4-controlled metabolic reprogramming.HuangQin Decoction Attenuates CPT-11-Induced Gastrointestinal Toxicity by Regulating Bile Acids Metabolism Homeostasis.Factors affecting separation and detection of bile acids by liquid chromatography coupled with mass spectrometry in negative mode.Inhibition of JNK signalling mediates PPARα-dependent protection against intrahepatic cholestasis by fenofibrate.Peroxisome Proliferator-Activated Receptor α Activation Suppresses Cytochrome P450 Induction Potential in Mice Treated with Gemfibrozil.Dual action of peroxisome proliferator-activated receptor alpha in perfluorodecanoic acid-induced hepatotoxicity.Alterations in biomechanical properties and microstructure of colon wall in early-stage experimental colitis.rSj16 Protects against DSS-Induced Colitis by Inhibiting the PPAR-α Signaling Pathway.Repression of intestinal transporters and FXR-FGF15 signaling explains bile acids dysregulation in experimental colitis-associated colon cancer.Contribution of Extracellular Matrix and Signal Mechanotransduction to Epithelial Cell Damage in Inflammatory Bowel Disease Patients: A Proteomic Study.Activation of intestinal GR-FXR and PPARα-UGT signaling exacerbates ibuprofen-induced enteropathy in mice.Editor's Highlight: Clofibrate Decreases Bile Acids in Livers of Male Mice by Increasing Biliary Bile Acid Excretion in a PPARα-Dependent Manner.Characterizing Factors Associated With Differences in FGF19 Blood Levels and Synthesis in Patients With Primary Bile Acid Diarrhea.Urinary Elimination of Bile Acid Glucuronides under Severe Cholestatic Situations: Contribution of Hepatic and Renal Glucuronidation Reactions.Detection technologies and metabolic profiling of bile acids: a comprehensive review.
P2860
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P2860
PPARα-UGT axis activation represses intestinal FXR-FGF15 feedback signalling and exacerbates experimental colitis.
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
PPARα-UGT axis activation repr ...... cerbates experimental colitis.
@ast
PPARα-UGT axis activation repr ...... cerbates experimental colitis.
@en
PPARα-UGT axis activation repr ...... cerbates experimental colitis.
@nl
type
label
PPARα-UGT axis activation repr ...... cerbates experimental colitis.
@ast
PPARα-UGT axis activation repr ...... cerbates experimental colitis.
@en
PPARα-UGT axis activation repr ...... cerbates experimental colitis.
@nl
prefLabel
PPARα-UGT axis activation repr ...... cerbates experimental colitis.
@ast
PPARα-UGT axis activation repr ...... cerbates experimental colitis.
@en
PPARα-UGT axis activation repr ...... cerbates experimental colitis.
@nl
P2093
P2860
P356
P1476
PPARα-UGT axis activation repr ...... acerbates experimental colitis
@en
P2093
Frank J Gonzalez
Guangji Wang
Kristopher W Krausz
Lijuan Cao
Xuefang Cheng
Xueyan Zhou
Yatrik M Shah
Yunpeng Qi
P2860
P2888
P356
10.1038/NCOMMS5573
P407
P577
2014-09-03T00:00:00Z
P5875
P6179
1022778164