Shuttling of initiating kinase between discrete aggregates of the high affinity receptor for IgE regulates the cellular response
about
The unique domain as the site on Lyn kinase for its constitutive association with the high affinity receptor for IgEInteraction between the unphosphorylated receptor with high affinity for IgE and Lyn kinase.Calculations show substantial serial engagement of T cell receptors.Perinatal stress, brain inflammation and risk of autism-review and proposal.The high-affinity IgE receptor (FcepsilonRI): a critical regulator of airway smooth muscle cells?A mechanistic model of early FcεRI signaling: lipid rafts and the question of protection from dephosphorylation.Molecular versatility of antibodies.A detailed mathematical model predicts that serial engagement of IgE-Fc epsilon RI complexes can enhance Syk activation in mast cells.Mathematical and computational models of immune-receptor signalling.Unexpected signals in a system subject to kinetic proofreading.Kinetic proofreading models for cell signaling predict ways to escape kinetic proofreading.Single-cell measurements of IgE-mediated FcεRI signaling using an integrated microfluidic platformKinetic proofreading of ligand-FcepsilonRI interactions may persist beyond LAT phosphorylation.Highly expressed cytoplasmic FcεRIβ in human mast cells functions as a negative regulator of the FcRγ-mediated cell activation signal.Too much of a good thing: beta-chain overexpression blocks FcεRI signalling by capturing Lyn in the cytosol.
P2860
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P2860
Shuttling of initiating kinase between discrete aggregates of the high affinity receptor for IgE regulates the cellular response
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Shuttling of initiating kinase ...... egulates the cellular response
@ast
Shuttling of initiating kinase ...... egulates the cellular response
@en
type
label
Shuttling of initiating kinase ...... egulates the cellular response
@ast
Shuttling of initiating kinase ...... egulates the cellular response
@en
prefLabel
Shuttling of initiating kinase ...... egulates the cellular response
@ast
Shuttling of initiating kinase ...... egulates the cellular response
@en
P2093
P2860
P356
P1476
Shuttling of initiating kinase ...... egulates the cellular response
@en
P2093
P2860
P304
P356
10.1073/PNAS.94.4.1372
P407
P577
1997-02-01T00:00:00Z