Liver-stage malaria parasites vulnerable to diverse chemical scaffolds.
about
Next-generation antimicrobials: from chemical biology to first-in-class drugsDrug repurposing and human parasitic protozoan diseasesRecent advances in malaria drug discoveryUsing genetic methods to define the targets of compounds with antimalarial activityThe ChEMBL bioactivity database: an updateAntimalarial drug discovery - approaches and progress towards new medicines.Identification of an Atg8-Atg3 protein-protein interaction inhibitor from the medicines for Malaria Venture Malaria Box active in blood and liver stage Plasmodium falciparum parasitesMuddled mechanisms: recent progress towards antimalarial target identificationEnlightening the malaria parasite life cycle: bioluminescent Plasmodium in fundamental and applied researchDevelopment and validation of a luminescence-based, medium-throughput assay for drug screening in Schistosoma mansoniDiscovery of Novel Liver-Stage Antimalarials through Quantum SimilaritySynergy of Omeprazole and Praziquantel In Vitro Treatment against Schistosoma mansoni Adult WormsHigh-Throughput Luciferase-Based Assay for the Discovery of Therapeutics That Prevent MalariaAre bigger data sets better for machine learning? Fusing single-point and dual-event dose response data for Mycobacterium tuberculosisNovel endoperoxide-based transmission-blocking antimalarials with liver- and blood-schizontocidal activitiesAntimalarial compounds in Phase II clinical development.Lansoprazole is an antituberculous prodrug targeting cytochrome bc1.Chemical interrogation of the malaria kinome.Dihydroquinazolinone inhibitors of proliferation of blood and liver stage malaria parasitesHuman iPSC-derived hepatocyte-like cells support Plasmodium liver-stage infection in vitro.Targeting the erythrocytic and liver stages of malaria parasites with s-triazine-based hybrids.Discovery of Dual-Stage Malaria Inhibitors with New Targets.Probing the Azaaurone Scaffold against the Hepatic and Erythrocytic Stages of Malaria Parasites.Antiinfectives targeting enzymes and the proton motive force.An ultrasensitive NanoLuc-based luminescence system for monitoring Plasmodium berghei throughout its life cycleCurrent therapies and future possibilities for drug development against liver-stage malaria.Assessment of dual life stage antiplasmodial activity of british seaweedsTREM2 governs Kupffer cell activation and explains belr1 genetic resistance to malaria liver stage infectionChemical signatures and new drug targets for gametocytocidal drug development.Hits, leads and drugs against malaria through diversity-oriented synthesis.N-Myristoyltransferase as a potential drug target in malaria and leishmaniasis.Novel approaches in antimalarial drug discovery.New insight-guided approaches to detect, cure, prevent and eliminate malaria.Inhibition of Plasmodium Hepatic Infection by Antiretroviral Compounds.Phenotypic Screens in Antimalarial Drug Discovery.Salinomycin and other ionophores as a new class of antimalarial drugs with transmission-blocking activity.Menoctone Resistance in Malaria Parasites Is Conferred by M133I Mutations in Cytochrome b That Are Transmissible through Mosquitoes.Single dose treatment of malaria - current status and perspectives.Potential of lichen secondary metabolites against Plasmodium liver stage parasites with FAS-II as the potential target.Realistically, how far are we from a universal malaria drug?
P2860
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P2860
Liver-stage malaria parasites vulnerable to diverse chemical scaffolds.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Liver-stage malaria parasites vulnerable to diverse chemical scaffolds.
@ast
Liver-stage malaria parasites vulnerable to diverse chemical scaffolds.
@en
type
label
Liver-stage malaria parasites vulnerable to diverse chemical scaffolds.
@ast
Liver-stage malaria parasites vulnerable to diverse chemical scaffolds.
@en
prefLabel
Liver-stage malaria parasites vulnerable to diverse chemical scaffolds.
@ast
Liver-stage malaria parasites vulnerable to diverse chemical scaffolds.
@en
P2860
P356
P1476
Liver-stage malaria parasites vulnerable to diverse chemical scaffolds.
@en
P2093
Emily R Derbyshire
Jon Clardy
P2860
P304
P356
10.1073/PNAS.1118370109
P407
P577
2012-05-14T00:00:00Z