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Lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brain injuryMitochondrial targeting of electron scavenging antioxidants: regulation of selective oxidation vs random chain reactionsEffects of tempol and redox-cycling nitroxides in models of oxidative stress.Chemistry and antihypertensive effects of tempol and other nitroxidesAltering the response to radiation: sensitizers and protectorsTempol moderately extends survival in a hSOD1(G93A) ALS rat model by inhibiting neuronal cell loss, oxidative damage and levels of non-native hSOD1(G93A) formsMitochondria as a target in treatmentSOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathwaysMitochondria-targeted antioxidant preserves contractile properties and mitochondrial function of skeletal muscle in aged ratsMitochondria-targeted ROS scavenger improves post-ischemic recovery of cardiac function and attenuates mitochondrial abnormalities in aged ratsThe impact of ionizing radiation on placental trophoblastsPotential implication of the chemical properties and bioactivity of nitrone spin traps for therapeuticsEffects of the antioxidant drug tempol on renal oxygenation in mice with reduced renal mass.Tempol-mediated activation of latent iron regulatory protein activity prevents symptoms of neurodegenerative disease in IRP2 knockout mice.Modulation of CEST images in vivo by T1 relaxation: a new approach in the design of responsive PARACEST agents.Dynamic nuclear polarization-magnetic resonance imaging at low ESR irradiation frequency for ascorbyl free radicals.Protective Effect of Tempol Against Hypoxia-Induced Oxidative Stress and Apoptosis in H9c2 Cells.Inhibition of myeloperoxidase-mediated hypochlorous acid production by nitroxidesLoss of TRPM2 function protects against irradiation-induced salivary gland dysfunctionDNA double-strand break repair genes and oxidative damage in brain metastasis of breast cancer.Evaluation of the fullerene compound DF-1 as a radiation protector.The mitochondria-targeted nitroxide JP4-039 augments potentially lethal irradiation damage repairSmall molecule GS-nitroxide ameliorates ionizing irradiation-induced delay in bone wound healing in a novel murine modelIn vivo imaging of tumor physiological, metabolic, and redox changes in response to the anti-angiogenic agent sunitinib: longitudinal assessment to identify transient vascular renormalization.Superoxide dismutase mimics: chemistry, pharmacology, and therapeutic potentialOxidative stress imaging in live animals with techniques based on electron paramagnetic resonance.Systemic DNA damage accumulation under in vivo tumor growth can be inhibited by the antioxidant TempolMagnetic resonance imaging of organic contrast agents in mice: capturing the whole-body redox landscape.The carbonylation and covalent dimerization of human superoxide dismutase 1 caused by its bicarbonate-dependent peroxidase activity is inhibited by the radical scavenger tempol.Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity.Iron regulatory protein 1 outcompetes iron regulatory protein 2 in regulating cellular iron homeostasis in response to nitric oxide.Antihypertensive effect of mitochondria-targeted proxyl nitroxidesDesign and synthesis of novel spin-labeled camptothecin derivatives as potent cytotoxic agentsOxidative stress in oral diseases.Nitroxide derivatives of non-steroidal anti-inflammatory drugs exert anti-inflammatory and superoxide dismutase scavenging properties in A459 cells.The antioxidant tempol reduces carcinogenesis and enhances survival in mice when administered after nonlethal total body radiation.Pulsed EPR imaging of nitroxides in mice.Dynamic nuclear polarization studies of nitroxyl spin probes in agarose gel using Overhauser-enhanced magnetic resonance imaging.Monitoring redox-sensitive paramagnetic contrast agent by EPRI, OMRI and MRI.Stable isotope- and mass spectrometry-based metabolomics as tools in drug metabolism: a study expanding tempol pharmacology.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
The chemistry and biology of nitroxide compounds.
@ast
The chemistry and biology of nitroxide compounds.
@en
type
label
The chemistry and biology of nitroxide compounds.
@ast
The chemistry and biology of nitroxide compounds.
@en
prefLabel
The chemistry and biology of nitroxide compounds.
@ast
The chemistry and biology of nitroxide compounds.
@en
P2093
P2860
P1476
The chemistry and biology of nitroxide compounds.
@en
P2093
Benjamin P Soule
Fuminori Hyodo
James B Mitchell
John A Cook
Ken-Ichiro Matsumoto
Murali C Krishna
Nicole L Simone
P2860
P304
P356
10.1016/J.FREERADBIOMED.2007.02.030
P577
2007-03-12T00:00:00Z