Drug discovery for malaria: a very challenging and timely endeavor
about
Parasitostatic effect of maslinic acid. I. Growth arrest of Plasmodium falciparum intraerythrocytic stagesSafety and immunogenicity of a malaria vaccine, Plasmodium falciparum AMA-1/MSP-1 chimeric protein formulated in montanide ISA 720 in healthy adultsKinases as druggable targets in trypanosomatid protozoan parasitesArtemisinins: their growing importance in medicineStructures of Falcipain-2 and Falcipain-3 Bound to Small Molecule Inhibitors: Implications for Substrate Specificity ‡The MYST family histone acetyltransferase regulates gene expression and cell cycle in malaria parasite Plasmodium falciparumModelling the impact of artemisinin combination therapy and long-acting treatments on malaria transmission intensityExpression, characterization, and cellular localization of knowpains, papain-like cysteine proteases of the Plasmodium knowlesi malaria parasiteDiversity-oriented natural product platform identifies plant constituents targeting Plasmodium falciparumSimplified Reversed Chloroquines To Overcome Malaria Resistance to Quinoline-Based DrugsPlasmodium dihydroorotate dehydrogenase: a promising target for novel anti-malarial chemotherapy.Synthesis of antitrypanosomal 1,2-dioxane derivatives based on a natural product scaffold.Recent progress in the development of anti-malarial quinolones.Synthesis and preliminary biological evaluation of a small library of hybrid compounds based on Ugi isocyanide multicomponent reactions with a marine natural product scaffold.In vitro and in vivo antimalarial activities of T-2307, a novel arylamidineAntimalarial peptides from marine cyanobacteria: isolation and structural elucidation of gallinamide A.Why do malaria parasites increase host erythrocyte permeability?Structural modifications of quinoline-based antimalarial agents: Recent developments.Advances in quantitative structure-activity relationship models of antimalarials.Synthesis of five- and six-membered cyclic organic peroxides: Key transformations into peroxide ring-retaining products.A single, low, oral dose of a 5-carbon-linked trioxane dimer orthoester plus mefloquine cures malaria-infected mice.Antimalarial Preclinical Drug Development: A Single Oral Dose of A 5-Carbon-linked Trioxane Dimer Plus Mefloquine Cures Malaria-Infected Mice.Malaria-Infected Mice Are Cured by a Single Low Dose of a New Silylamide Trioxane Plus Mefloquine.Identification and characterization of the antiplasmodial activity of Hsp90 inhibitors.Screening of agelasine D and analogs for inhibitory activity against pathogenic protozoa; identification of hits for visceral leishmaniasis and Chagas disease.Malaria-infected mice are cured by a single oral dose of new dimeric trioxane sulfones which are also selectively and powerfully cytotoxic to cancer cells.Evaluation of herbal antimalarial MAMA decoction-amodiaquine combination in murine malaria model.Stereoelectronic source of the anomalous stability of bis-peroxides.Investigations into the role of the Plasmodium falciparum SERCA (PfATP6) L263E mutation in artemisinin action and resistance.Malarial parasite pathogenesis and drug targets.In Silico Designing and Analysis of Inhibitors against Target Protein Identified through Host-Pathogen Protein Interactions in Malaria.Cell-based optimization of novel benzamides as potential antimalarial leads.Concise synthesis and antimalarial activity of all four mefloquine stereoisomers using a highly enantioselective catalytic borylative alkene isomerization.Development in Assay Methods for in Vitro Antimalarial Drug Efficacy Testing: A Systematic Review.Peroxides with Anthelmintic, Antiprotozoal, Fungicidal and Antiviral Bioactivity: Properties, Synthesis and Reactions.Formulation and characterization of atovaquone nanosuspension for improved oral delivery in the treatment of malaria.Stereoelectronic Control in the Ozone-Free Synthesis of Ozonides.Concise Synthesis and Antimalarial Activity of All Four Mefloquine Stereoisomers Using a Highly Enantioselective Catalytic Borylative Alkene IsomerizationStereoelectronic Control in the Ozone-Free Synthesis of Ozonides
P2860
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P2860
Drug discovery for malaria: a very challenging and timely endeavor
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Drug discovery for malaria: a very challenging and timely endeavor
@ast
Drug discovery for malaria: a very challenging and timely endeavor
@en
type
label
Drug discovery for malaria: a very challenging and timely endeavor
@ast
Drug discovery for malaria: a very challenging and timely endeavor
@en
prefLabel
Drug discovery for malaria: a very challenging and timely endeavor
@ast
Drug discovery for malaria: a very challenging and timely endeavor
@en
P2860
P1476
Drug discovery for malaria: a very challenging and timely endeavor
@en
P2860
P304
P356
10.1016/J.CBPA.2007.05.038
P577
2007-08-01T00:00:00Z