Epigenetic reprogramming reverses the relapse-specific gene expression signature and restores chemosensitivity in childhood B-lymphoblastic leukemia. - Wikidata - awgldk - TriplyDB

Epigenetic reprogramming reverses the relapse-specific gene expression signature and restores chemosensitivity in childhood B-lymphoblastic leukemia.

Epigenetic reprogramming reverses the relapse-specific gene expression signature and restores chemosensitivity in childhood B-lymphoblastic leukemia.

http://www.wikidata.org/entity/Q36015007

about

Is lineage decision-making restricted during tumoral reprograming of haematopoietic stem cells?Potential Gene Interactions in the Cell Cycles of Gametes, Zygotes, Embryonic Stem Cells and the Development of Cancer Tumor-Derived Cell Lines as Molecular Models of Cancer Pharmacogenomics Current concepts in pediatric Philadelphia chromosome-positive acute lymphoblastic leukemia New Therapeutic Strategies in Acute Lymphocytic Leukemia.Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia.Genetic methylation and lymphoid malignancies: biomarkers of tumor progression and targeted therapy.Loss of TBL1XR1 disrupts glucocorticoid receptor recruitment to chromatin and results in glucocorticoid resistance in a B-lymphoblastic leukemia model.A therapeutic trial of decitabine and vorinostat in combination with chemotherapy for relapsed/refractory acute lymphoblastic leukemia.A novel molecular mechanism involved in multiple myeloma development revealed by targeting MafB to haematopoietic progenitors.Wnt inhibition leads to improved chemosensitivity in paediatric acute lymphoblastic leukaemia A phase I study of EZN-3042, a novel survivin messenger ribonucleic acid (mRNA) antagonist, administered in combination with chemotherapy in children with relapsed acute lymphoblastic leukemia (ALL): a report from the therapeutic advances in childho Biology of childhood acute lymphoblastic leukemia.The biology of relapsed acute lymphoblastic leukemia: opportunities for therapeutic interventions.Generation of tumor antigen-specific T cell lines from pediatric patients with acute lymphoblastic leukemia--implications for immunotherapy.Novel agents for the treatment of childhood acute leukemia.FOXM1 is overexpressed in B-acute lymphoblastic leukemia (B-ALL) and its inhibition sensitizes B-ALL cells to chemotherapeutic drugs Treatment of infant leukemias: challenge and promise.Concerted changes in transcriptional regulation of genes involved in DNA methylation, demethylation, and folate-mediated one-carbon metabolism pathways in the NCI-60 cancer cell line panel in response to cancer drug treatment The future of epigenetic therapy in solid tumours--lessons from the past.Impact of aberrant DNA methylation patterns including CYP1B1 methylation in adolescents and young adults with acute lymphocytic leukemia.The Role of Histone Protein Modifications and Mutations in Histone Modifiers in Pediatric B-Cell Progenitor Acute Lymphoblastic Leukemia.MLL-Rearranged Leukemias-An Update on Science and Clinical Approaches.Function of oncogenes in cancer development: a changing paradigm.Novel targeted therapies in acute lymphoblastic leukemia.Epigenetic regulation of cell signaling pathways in acute lymphoblastic leukemia.Epigenetic modifications in pediatric acute lymphoblastic leukemia.Genomic and pharmacogenetic studies of childhood acute lymphoblastic leukemia.Clonal selection and therapy resistance in acute leukaemias: mathematical modelling explains different proliferation patterns at diagnosis and relapse.Towards an understanding of the biology and targeted treatment of paediatric relapsed acute lymphoblastic leukaemia.Erase and Rewind: Epigenetic Conversion of Cell Fate.Emerging immunotherapy in pediatric lymphoma.Addressing intra-tumoral heterogeneity and therapy resistance.Rapamycin restores p14, p15 and p57 expression and inhibits the mTOR/p70S6K pathway in acute lymphoblastic leukemia cells.Epigenetic drug combination overcomes osteoblast-induced chemoprotection in pediatric acute lymphoid leukemia.DNA methylation of membrane-bound tyrosine phosphatase genes in acute lymphoblastic leukaemia.Influence of Histone Deacetylase Inhibitors and DNA-Methyltransferase Inhibitors on the NK Cell-Mediated Lysis of Pediatric B-Lineage Leukemia.Decitabine-based chemotherapy followed by haploidentical lymphocyte infusion improves the effectiveness in elderly patients with acute myeloid leukemia Decitabine-Vorinostat combination treatment in acute myeloid leukemia activates pathways with potential for novel triple therapy.Epigenetic control of epithelial-mesenchymal-transition in human cancer.

P2860

Q26779702-83B04EB2-1E2C-42AB-8761-8C1CCAE39808 Q26781101-0D1D54F7-8DBF-4B7E-AB37-35F8E317F785 Q26801410-14355D85-6F38-440D-AFDB-5E1226F4E76D Q27025242-5CBCB015-0FE7-436D-8F18-D69E960D5C48 Q30252776-58DADA4E-1E5D-4AEE-803A-16C13E460343 Q33585130-576E0EEE-8283-4C4A-B80A-BEFB33EC7B8A Q33913937-51DF5FF2-5805-4BB8-876A-A6480A931BCA Q33946996-5712ED92-FC22-4B9B-A679-C647C45D450C Q34052660-DA1B657E-8AEB-4687-ABD2-87B13B48A93D Q34383712-4A03539E-970F-43B1-A093-CEDD37F859F9 Q34393633-5442BB94-9699-44C5-AB0D-B4729346573F Q34547528-784EAEE4-23DE-4134-900F-E7AEDF094827 Q34605953-E3F60421-8ACE-41E1-A6F5-384BF56F80F8 Q34687627-E19FEC46-51A8-4C70-AFE5-CE7EE8B6A6F4 Q34803707-94C771CA-0334-4F92-9F7D-981ED6860BCF Q35192790-59B2352C-7C0F-4037-9048-708BCA26CEA2 Q36094104-B77082B5-0036-4B77-A314-C8704D169200 Q36508988-C42EE746-B670-45FE-A839-BEE7E63BE2B7 Q37035513-C933CE1B-E561-4B5F-A5A0-5C383EF6BE53 Q37061554-218B3845-FEE7-4DCE-8A55-3CD5437A8EF7 Q37627410-D37DE1B3-C362-40FB-94A1-5BE43EDEE5CE Q37629537-EF6D2A57-FA88-4E2B-A651-F7DF64E25023 Q37633585-DE5D7542-ED59-49EF-9EA0-DF816F2ED3E6 Q38103175-9F40927E-6A62-4603-9344-7C5624676A6C Q38120551-C93B0F51-2F9D-4883-B372-BCC26BE2FD76 Q38141135-1E52EA92-2D22-438E-8DD2-69FA70F08FE2 Q38214773-E557774D-3DDC-4470-8E32-CBE62CE0B2A5 Q38289596-23095685-42F8-4064-982C-87F7963B3B97 Q38594523-3B57511A-AC9C-44EA-A621-5ED7945A43E0 Q38633437-A403F635-3599-4637-9F05-49567F52322F Q38640670-46197AC5-BDA4-4317-8024-A6BBCA7B1E55 Q38652326-F9F8CF92-0F89-46A5-8167-DD999B034532 Q38823179-3883AEE0-238A-4CEA-BDDD-23F3F9CF2FBA Q38835910-7C45C96B-5FC6-462A-8FBD-A615340A6B48 Q38973962-8AF105D4-4915-413F-9519-213E6F90315A Q39094566-CAB70E9B-9069-4796-81A4-890AE9F91081 Q39156647-2A6F2ABE-ECB0-4FB3-BB47-EE002655096D Q41593326-5069E0BC-ACB7-4676-A78E-F3CF2A01098D Q41612823-8E0CC3A5-F86C-480F-94B3-7DCFBA0948BC Q42409031-3292E7DC-2781-43C5-B48B-1B27BFB3FDD8

P2860

Epigenetic reprogramming reverses the relapse-specific gene expression signature and restores chemosensitivity in childhood B-lymphoblastic leukemia.

http://www.wikidata.org/entity/Q36015007

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年学术文章

@wuu

2012年学术文章

@zh-cn

2012年学术文章

@zh-hans

2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

2012年學術文章

@zh

2012年學術文章

@zh-hant

name

Epigenetic reprogramming rever ...... hood B-lymphoblastic leukemia.

@ast

Epigenetic reprogramming rever ...... hood B-lymphoblastic leukemia.

@en

type

label

Epigenetic reprogramming rever ...... hood B-lymphoblastic leukemia.

@ast

Epigenetic reprogramming rever ...... hood B-lymphoblastic leukemia.

@en

prefLabel

Epigenetic reprogramming rever ...... hood B-lymphoblastic leukemia.

@ast

Epigenetic reprogramming rever ...... hood B-lymphoblastic leukemia.

@en

P1433

Q36015007-2AC408C4-DAAD-4C40-9144-C126576FAC70

P1476

Q36015007-DA00EBB9-FB57-4594-A718-0EFDB3034220

P2093

Q36015007-1BFC5DE9-29DB-4AC4-B1A2-2E3319D6209F

Q36015007-39388459-81D8-47D8-89D9-8E055E1F6D82

Q36015007-9884E1CC-02A0-4B1D-ABFF-1A5852F114F2

Q36015007-B0356A02-0224-423E-ABB1-1278CD2E3785

Q36015007-D9DEF7CA-1817-48A3-8CFA-CD63775231FB

Q36015007-DB7A5782-20E9-4461-A136-1528B93916F0

Q36015007-E51B1D27-ECC9-416A-BE16-80C88D321844

P2860

Q36015007-0262437C-2144-4CFA-9D18-35DB9659D7CC

Q36015007-0728CB51-1B86-40E3-B0C0-807F38EC6EA8

Q36015007-07905F06-7E35-447B-9EF4-46BF19D3EFF6

Q36015007-0FC5C3BB-54DB-4956-9D26-6423379895D0

Q36015007-10A82DEE-672B-4ADE-8BA4-75CE35AB3881

Q36015007-161DFC3F-9B06-4161-AC78-E98DAF3FE29B

Q36015007-17322F3C-6042-44B5-864E-E6CF7F870F26

Q36015007-19B6EA45-219D-4DA6-A89E-DACF71CB6971

Q36015007-1EDBA681-924B-4F4C-B790-23E2A3CBF163

Q36015007-21555D68-9332-477B-AF15-FD81BD473DE7

P304

Q36015007-BBB24074-C19C-423D-B707-436711E43621

P31

Q36015007-1C1DBA87-534B-49D0-AD01-26D38F6580CB

P356

Q36015007-26FC7556-E119-4975-8586-F55D99DA2D1E

P407

Q36015007-81EEA7E2-8318-4F49-A2DC-E8C8DB23AC02

P433

Q36015007-AE005920-96CB-4D8F-9A44-F40A0CB06406

P478

Q36015007-54C7A342-B151-4C9E-8D70-057CA1FD65C8

P577

Q36015007-BF7AEABB-0438-457D-B0BE-A0D7BB4751EF

P698

Q36015007-8020AAA5-FAE7-4879-846C-610D1B662FC4

P932

Q36015007-0C18D3CD-52B9-40A3-A4A4-B8B2CDC4F4E3

P356

BLOOD-2012-01-401687

P1433

P1476

Epigenetic reprogramming rever ...... hood B-lymphoblastic leukemia.

@en

P2093

Debra J Morrison

http://www.w3.org/2001/XMLSchema#string

Elizabeth A Raetz

http://www.w3.org/2001/XMLSchema#string

Jinhua Wang

http://www.w3.org/2001/XMLSchema#string

Michael J Burke

http://www.w3.org/2001/XMLSchema#string

Patrick Brown

http://www.w3.org/2001/XMLSchema#string

Teena Bhatla

http://www.w3.org/2001/XMLSchema#string

William L Carroll

http://www.w3.org/2001/XMLSchema#string

P2860

Translating the Histone Code

DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

Protein tyrosine phosphatase receptor-type O (PTPRO) exhibits characteristics of a candidate tumor suppressor in human lung cancer

The genomic landscapes of human breast and colorectal cancers

DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters

DNA methyltransferase Dnmt1 associates with histone deacetylase activity

The epigenomics of cancer

A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer

FoxM1B is overexpressed in human glioblastomas and critically regulates the tumorigenicity of glioma cells

The Connectivity Map: a new tool for biomedical research

P304

5201-5210

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1182/BLOOD-2012-01-401687

http://www.w3.org/2001/XMLSchema#string

P407

P433

22

http://www.w3.org/2001/XMLSchema#string

P478

119

http://www.w3.org/2001/XMLSchema#string

P577

2012-04-11T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

22496163

http://www.w3.org/2001/XMLSchema#string

P932

3369610

http://www.w3.org/2001/XMLSchema#string