A platform for the discovery of new macrolide antibiotics. - Wikidata - awgldk - TriplyDB

A platform for the discovery of new macrolide antibiotics.

A platform for the discovery of new macrolide antibiotics.

http://www.wikidata.org/entity/Q36021739

about

Macrolide Resistance in Streptococcus pneumoniae Parameter identifiability-based optimal observation remedy for biological networks.Ring-Expansion Approach to Medium-Sized Lactams and Analysis of Their Medicinal Lead-Like Properties.Novel, male-produced aggregation pheromone of the cerambycid beetle Rosalia alpina, a priority species of European conservation concern.Total syntheses of the archazolids: an emerging class of novel anticancer drugs.Navigating the Chiral Pool in the Total Synthesis of Complex Terpene Natural Products.Functional Metagenomics as a Tool for Identification of New Antibiotic Resistance Genes from Natural Environments.Strategies for the Discovery and Development of New Antibiotics from Natural Products: Three Case Studies.Nature nurtures the design of new semi-synthetic macrolide antibiotics.Ring-Expansion Reactions in the Synthesis of Macrocycles and Medium-Sized Rings.Total Syntheses of Vancomycin-Related Glycopeptide Antibiotics and Key Analogues.Applications of Nonenzymatic Catalysts to the Alteration of Natural Products.The macrolide antibiotic renaissance.Natural product analogues: towards a blueprint for analogue-focused synthesis.Convection shapes the trade-off between antibiotic efficacy and the selection for resistance in spatial gradients.Macrolides selectively inhibit mutant KCNJ5 potassium channels that cause aldosterone-producing adenoma.Tetrazine Marks the Spot Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides.Drug discovery: Fighting evolution with chemical synthesis.Synthesis of Cyclic Peptide Mimetics by the Successive Ring Expansion of Lactams.Are highly morphed peptide frameworks lurking silently in microbial genomes valuable as next generation antibiotic scaffolds?Scalable Access to Arylomycins via C-H Functionalization Logic.Leptolyngbyolides, Cytotoxic Macrolides from the Marine Cyanobacterium Leptolyngbya sp.: Isolation, Biological Activity, and Catalytic Asymmetric Total Synthesis.Natural Products as Platforms To Overcome Antibiotic Resistance.The evolution of substrate discrimination in macrolide antibiotic resistance enzymes.Synthesis and Antibacterial Evaluation of a Series of 11,12-Cyclic Carbonate Azithromycin-3-O-descladinosyl-3-O-carbamoyl Glycosyl Derivatives.Large-scale preparation of key building blocks for the manufacture of fully synthetic macrolide antibiotics.Look and Outlook on Enzyme-Mediated Macrolide Resistance Ribosomal stalling landscapes revealed by high-throughput inverse toeprinting of mRNA libraries Hundreds of antibiotics built from scratch

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A platform for the discovery of new macrolide antibiotics.

http://www.wikidata.org/entity/Q36021739

description

2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

@zh

2016年论文

@zh-cn

name

A platform for the discovery of new macrolide antibiotics.

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A platform for the discovery of new macrolide antibiotics.

@en

type

label

A platform for the discovery of new macrolide antibiotics.

@ast

A platform for the discovery of new macrolide antibiotics.

@en

prefLabel

A platform for the discovery of new macrolide antibiotics.

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A platform for the discovery of new macrolide antibiotics.

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A platform for the discovery of new macrolide antibiotics

@en

P2093

Andrew G Myers

http://www.w3.org/2001/XMLSchema#string

Audrey Langlois-Mercier

http://www.w3.org/2001/XMLSchema#string

Daniel T Hog

http://www.w3.org/2001/XMLSchema#string

Ian B Seiple

http://www.w3.org/2001/XMLSchema#string

Peter M Wright

http://www.w3.org/2001/XMLSchema#string

Peter N Carlsen

http://www.w3.org/2001/XMLSchema#string

Senkara Rao Allu

http://www.w3.org/2001/XMLSchema#string

Takehiro Fukuzaki

http://www.w3.org/2001/XMLSchema#string

William D Green

http://www.w3.org/2001/XMLSchema#string

Xiang Zhou

http://www.w3.org/2001/XMLSchema#string

P2860

Binding and action of CEM-101, a new fluoroketolide antibiotic that inhibits protein synthesis

Structural Insight into the Antibiotic Action of Telithromycin against Resistant Mutants

Revisiting the structures of several antibiotics bound to the bacterial ribosome

A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes

NEW ALDOL TYPE REACTION

Antibiotics for emerging pathogens

CEM-101, a novel fluoroketolide: antimicrobial activity against a diverse collection of Gram-positive and Gram-negative bacteria.

Ketolides-telithromycin, an example of a new class of antibacterial agents.

Stereocontrolled synthesis of syn-β-Hydroxy-α-amino acids by direct aldolization of pseudoephenamine glycinamide.

The evolving role of chemical synthesis in antibacterial drug discovery.

P2888

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338-345

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10.1038/NATURE17967

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7603

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P478

533

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Matthew L Condakes

Filip T Szczypiński

Yoshiaki Kitamura

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2016-05-01T00:00:00Z

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1047068189

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27193679

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6526944

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