An Allosteric Interaction Links USP7 to Deubiquitination and Chromatin Targeting of UHRF1.
about
Signalling pathways in UHRF1-dependent regulation of tumor suppressor genes in cancerHemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1Data in support of UbSRD: The Ubiquitin Structural Relational Database.Stable Isotope Labeling with Amino Acids (SILAC)-Based Proteomics of Primary Human Kidney Cells Reveals a Novel Link between Male Sex Hormones and Impaired Energy Metabolism in Diabetic Kidney Disease.Ubiquitin-specific protease 7 expression is a prognostic factor in epithelial ovarian cancer and correlates with lymph node metastasis.Whole-transcriptome analysis of UUO mouse model of renal fibrosis reveals new molecular players in kidney diseasesZinc Finger Protein 618 Regulates the Function of UHRF2 (Ubiquitin-like with PHD and Ring Finger Domains 2) as a Specific 5-Hydroxymethylcytosine ReaderThe epigenetic integrator UHRF1: on the road to become a universal biomarker for cancer.Protein deubiquitinase USP7 is required for osteogenic differentiation of human adipose-derived stem cells.Regulation of Ubiquitin-like with Plant Homeodomain and RING Finger Domain 1 (UHRF1) Protein Stability by Heat Shock Protein 90 Chaperone Machinery.Usp7-dependent histone H3 deubiquitylation regulates maintenance of DNA methylation.Dual-utility NLS drives RNF169-dependent DNA damage responses.Conformational dynamics of the TTD-PHD histone reader module of the UHRF1 epigenetic regulator reveals multiple histone-binding states, allosteric regulation, and druggability.Active site-targeted covalent irreversible inhibitors of USP7 impair the functions of Foxp3+ T-regulatory cells by promoting ubiquitination of Tip60.The CUE1 domain of the SNF2-like chromatin remodeler SMARCAD1 mediates its association with KRAB-associated protein 1 (KAP1) and KAP1 target genes.Interaction of the epigenetic integrator UHRF1 with the MYST domain of TIP60 inside the cell.An Intramolecular Interaction of UHRF1 Reveals Dual Control for Its Histone Association.Thymoquinone challenges UHRF1 to commit auto-ubiquitination: a key event for apoptosis induction in cancer cells.Critical Role of the UBL Domain in Stimulating the E3 Ubiquitin Ligase Activity of UHRF1 toward Chromatin
P2860
Q28073257-474D175B-0F41-4E90-9A29-6B75AA6A2D86Q28831238-C01DB99A-653D-46D0-AFC8-547D8B9D14C2Q31055481-BDEE6E85-1BE2-4A88-BC32-C34F37608425Q36243548-82ADDD3C-16EE-43DB-9E90-AA23D26A6A30Q36716292-72924D6A-1ADF-457E-82E4-3F7D9A0BC408Q36910595-097D739E-89A7-414F-BFBD-8CD4933FA6CEQ37034418-61BCD067-D638-4DA7-BC82-3CE242A46EE8Q39304639-8CE397E4-7656-40D8-95E2-3D1D40F54FC2Q40495744-DB3EA8C3-2D3F-4BCC-B9A7-F6DEB8ACDA67Q41106970-95B08C66-55D2-43E9-9D8E-32ED630E6023Q42270028-2CA84FC2-671A-4AF7-A8F1-B9660D120F6FQ42291846-6BA2611E-BF10-42F2-B14F-390B11D731B2Q47103361-9030F93D-8A46-460A-8C09-DE6CA74F4A97Q47135501-2E948D2B-8EF6-40B3-B44D-A8B21F23C3CDQ47248814-069CEA8C-5248-40EC-AC27-608C4372D297Q47263859-FFEE272B-DDC7-4E9B-995B-FCA8F3A8F271Q50207902-BE3C21D7-E6B8-46A2-BADB-8879131F6032Q55445741-2F34BF50-70E5-4831-A413-F207DBEC1213Q58560680-2882603F-3ACF-471F-B027-78295B652D63
P2860
An Allosteric Interaction Links USP7 to Deubiquitination and Chromatin Targeting of UHRF1.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
An Allosteric Interaction Link ...... Chromatin Targeting of UHRF1.
@ast
An Allosteric Interaction Link ...... Chromatin Targeting of UHRF1.
@en
type
label
An Allosteric Interaction Link ...... Chromatin Targeting of UHRF1.
@ast
An Allosteric Interaction Link ...... Chromatin Targeting of UHRF1.
@en
prefLabel
An Allosteric Interaction Link ...... Chromatin Targeting of UHRF1.
@ast
An Allosteric Interaction Link ...... Chromatin Targeting of UHRF1.
@en
P2093
P2860
P50
P1433
P1476
An Allosteric Interaction Link ...... Chromatin Targeting of UHRF1.
@en
P2093
David F Allison
Gang Greg Wang
Jikui Song
Yinsheng Wang
Zhi-Min Zhang
P2860
P304
P356
10.1016/J.CELREP.2015.07.046
P577
2015-08-19T00:00:00Z