Ligand control of coregulator recruitment to nuclear receptors.
about
Human Ccr4-Not complex is a ligand-dependent repressor of nuclear receptor-mediated transcriptionStructural basis for hydroxycholesterols as natural ligands of orphan nuclear receptor RORgammaZNF366 is an estrogen receptor corepressor that acts through CtBP and histone deacetylasesThe receptor concept: pharmacology's big ideaThe cell-specific activity of the estrogen receptor alpha may be fine-tuned by phosphorylation-induced structural gymnastics.Unlock the Thermogenic Potential of Adipose Tissue: Pharmacological Modulation and Implications for Treatment of Diabetes and ObesityPost-translational modifications of the progesterone receptorsCyclopia extracts act as ERα antagonists and ERβ agonists, in vitro and in vivoInsights into the mechanism of partial agonism: crystal structures of the peroxisome proliferator-activated receptor gamma ligand-binding domain in the complex with two enantiomeric ligandsThe 2.0 Å crystal structure of the ERα ligand-binding domain complexed with lasofoxifeneStructural plasticity in the oestrogen receptor ligand-binding domainA surface on the androgen receptor that allosterically regulates coactivator bindingIdentification of a potent synthetic FXR agonist with an unexpected mode of binding and activationCommunication between the ERRalpha homodimer interface and the PGC-1alpha binding surface via the helix 8-9 loopStructure of Rev-erbα bound to N-CoR reveals a unique mechanism of nuclear receptor–co-repressor interactionLigand-binding dynamics rewire cellular signaling via estrogen receptor-αMedium Chain Fatty Acids Are Selective Peroxisome Proliferator Activated Receptor (PPAR) γ Activators and Pan-PPAR Partial AgonistsResveratrol modulates the inflammatory response via an estrogen receptor-signal integration networkStructure of the retinoid X receptor α-liver X receptor β (RXRα-LXRβ) heterodimer on DNAThe transcription factor Pax5 regulates its target genes by recruiting chromatin-modifying proteins in committed B cellsGain-of-Function Alleles in Caenorhabditis elegans Nuclear Hormone Receptor nhr-49 Are Functionally DistinctPredictive features of ligand-specific signaling through the estrogen receptorTransactivation Function-2 of Estrogen Receptor α Contains Transactivation Function-1-regulating ElementTime-resolved expression profiling of the nuclear receptor superfamily in human adipogenesis.Screening for peptide drugs from the natural repertoire of biodiverse protein folds.PPARalpha-mediated effects of dietary lipids on intestinal barrier gene expression.Improved docking, screening and selectivity prediction for small molecule nuclear receptor modulators using conformational ensembles.Ligand dissociation from estrogen receptor is mediated by receptor dimerization: evidence from molecular dynamics simulationsPotential activity of fevicordin-A from Phaleria macrocarpa (Scheff) Boerl. seeds as estrogen receptor antagonist based on cytotoxicity and molecular modelling studies.Diosgenin relieves goiter via the inhibition of thyrocyte proliferation in a mouse model of Graves' disease.Cooperative activation of cyclin D1 and progesterone receptor gene expression by the SRC-3 coactivator and SMRT corepressor.Methods for the Analysis of High Precision Differential Hydrogen Deuterium Exchange Data.Progestogens used in postmenopausal hormone therapy: differences in their pharmacological properties, intracellular actions, and clinical effectsStructural and functional insights into nuclear receptor signaling.Molecular dynamics simulations reveal multiple pathways of ligand dissociation from thyroid hormone receptors.Estrogen-occupied estrogen receptor represses cyclin G2 gene expression and recruits a repressor complex at the cyclin G2 promoter.The tailless nuclear receptor acts as a dedicated repressor in the early Drosophila embryoDifferential hydrogen/deuterium exchange mass spectrometry analysis of protein-ligand interactionsSteroid receptor coactivators 1, 2, and 3: critical regulators of nuclear receptor activity and steroid receptor modulator (SRM)-based cancer therapyICI 182,780 has agonistic effects and synergizes with estradiol-17 beta in fish liver, but not in testis.
P2860
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P2860
Ligand control of coregulator recruitment to nuclear receptors.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Ligand control of coregulator recruitment to nuclear receptors.
@ast
Ligand control of coregulator recruitment to nuclear receptors.
@en
type
label
Ligand control of coregulator recruitment to nuclear receptors.
@ast
Ligand control of coregulator recruitment to nuclear receptors.
@en
prefLabel
Ligand control of coregulator recruitment to nuclear receptors.
@ast
Ligand control of coregulator recruitment to nuclear receptors.
@en
P1476
Ligand control of coregulator recruitment to nuclear receptors.
@en
P2093
Geoffrey L Greene
Kendall W Nettles
P304
P356
10.1146/ANNUREV.PHYSIOL.66.032802.154710
P577
2005-01-01T00:00:00Z