Oncogenicity of the developmental transcription factor Sox9.
about
A review on hepatocyte nuclear factor-1beta and tumorFucoxanthin and Its Metabolite Fucoxanthinol in Cancer Prevention and TreatmentRole of SOX family of transcription factors in central nervous system tumorsSOX9 inhibits β-TrCP-mediated protein degradation to promote nuclear GLI1 expression and cancer stem cell properties.Stratification and therapeutic potential of PML in metastatic breast cancerSOX9-regulated cell plasticity in colorectal metastasis is attenuated by rapamycinFBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastomaThe Tumor-Associated Glycosyltransferase ST6Gal-I Regulates Stem Cell Transcription Factors and Confers a Cancer Stem Cell PhenotypePrognostic Significance of β-Catenin, E-Cadherin, and SOX9 in Colorectal Cancer: Results from a Large Population-Representative Series.In Vivo Characterization of an AHR-Dependent Long Noncoding RNA Required for Proper Sox9b Expression.High expression of SOX2 is associated with poor prognosis in patients with salivary gland adenoid cystic carcinomaIn mammalian foetal testes, SOX9 regulates expression of its target genes by binding to genomic regions with conserved signatures.Sox9 mediates Notch1-induced mesenchymal features in lung adenocarcinoma.SOX9 regulates multiple genes in chondrocytes, including genes encoding ECM proteins, ECM modification enzymes, receptors, and transporters.Linking signaling pathways to transcriptional programs in breast cancer.SOX9 accelerates ESC differentiation to three germ layer lineages by repressing SOX2 expression through P21 (WAF1/CIP1)The SOX9 upstream region prone to chromosomal aberrations causing campomelic dysplasia contains multiple cartilage enhancers.Inhibition of autophagy exerts anti-colon cancer effects via apoptosis induced by p53 activation and ER stress.Activation of two distinct Sox9-EGFP-expressing intestinal stem cell populations during crypt regeneration after irradiation.Alteration of colonic stem cell gene signatures during the regenerative response to injuryChronic epithelial NF-κB activation accelerates APC loss and intestinal tumor initiation through iNOS up-regulationDecreased expression of SOX9 indicates a better prognosis and inhibits the growth of glioma cells by inducing cell cycle arrestMesoderm-specific Stat3 deletion affects expression of Sox9 yielding Sox9-dependent phenotypes.Identification of the interplay between SOX9 and S100P in the metastasis and invasion of colon carcinoma.SOX9, a potential tumor suppressor in cervical cancer, transactivates p21WAF1/CIP1 and suppresses cervical tumor growth.The role of Sox genes in lung morphogenesis and cancer.Upregulation of sex-determining region Y-box 9 (SOX9) promotes cell proliferation and tumorigenicity in esophageal squamous cell carcinoma.ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancerA far-upstream (-70 kb) enhancer mediates Sox9 auto-regulation in somatic tissues during development and adult regeneration.KLF4 and SOX9 transcription factors antagonize β-catenin and inhibit TCF-activity in cancer cells.SOX9 directly regulates IGFBP-4 in the intestinal epithelium.Notch-induced transcription factors are predictive of survival and 5-fluorouracil response in colorectal cancer patients.Epigenetic regulation of SOX9 by the NF-κB signaling pathway in pancreatic cancer stem cells.Sox9 confers stemness properties in hepatocellular carcinoma through Frizzled-7 mediated Wnt/β-catenin signalingSilencing of SOX12 by shRNA suppresses migration, invasion and proliferation of breast cancer cells.SOX9 indirectly regulates CEACAM1 expression and immune resistance in melanoma cells.SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage.Recurrent, truncating SOX9 mutations are associated with SOX9 overexpression, KRAS mutation, and TP53 wild type status in colorectal carcinoma.MicroRNA-101 inhibits proliferation, migration and invasion of human glioblastoma by targeting SOX9.The SOX family of genes in cancer development: biological relevance and opportunities for therapy.
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Oncogenicity of the developmental transcription factor Sox9.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Oncogenicity of the developmental transcription factor Sox9.
@ast
Oncogenicity of the developmental transcription factor Sox9.
@en
type
label
Oncogenicity of the developmental transcription factor Sox9.
@ast
Oncogenicity of the developmental transcription factor Sox9.
@en
prefLabel
Oncogenicity of the developmental transcription factor Sox9.
@ast
Oncogenicity of the developmental transcription factor Sox9.
@en
P2093
P2860
P50
P1433
P1476
Oncogenicity of the developmental transcription factor Sox9.
@en
P2093
Adolfo López de Munain
Ander Matheu
Angela J Tye
Clare Wise
Kathryn S E Cheah
Lina Cekaite
Marta Canamero
Robin Lovell-Badge
P2860
P304
P356
10.1158/0008-5472.CAN-11-3660
P407
P50
P577
2012-01-13T00:00:00Z