Peroxisome proliferator-activated receptor alpha induction of uncoupling protein 2 protects against acetaminophen-induced liver toxicity. - Wikidata - awgldk - TriplyDB

Peroxisome proliferator-activated receptor alpha induction of uncoupling protein 2 protects against acetaminophen-induced liver toxicity.

Peroxisome proliferator-activated receptor alpha induction of uncoupling protein 2 protects against acetaminophen-induced liver toxicity.

http://www.wikidata.org/entity/Q36044209

about

Being right on Q: shaping eukaryotic evolution Transgenic mice and metabolomics for study of hepatic xenobiotic metabolism and toxicity Developmental Sex Differences in the Metabolism of Cardiolipin in Mouse Cerebral Cortex Mitochondria Metabolic phenotype-microRNA data fusion analysis of the systemic consequences of Roux-en-Y gastric bypass surgery Ketone Body Therapy Protects From Lipotoxicity and Acute Liver Failure Upon Pparα Deficiency Clinical application of transcriptional activators of bile salt transporters.Peroxisome proliferator-activated receptor α, a potential therapeutic target for alcoholic liver disease.Alzheimer's disease: relevant molecular and physiopathological events affecting amyloid-β brain balance and the putative role of PPARs.Saikosaponin d protects against acetaminophen-induced hepatotoxicity by inhibiting NF-κB and STAT3 signaling Bee venom phospholipase A2 protects against acetaminophen-induced acute liver injury by modulating regulatory T cells and IL-10 in mice.TGF-β-SMAD3 signaling mediates hepatic bile acid and phospholipid metabolism following lithocholic acid-induced liver injury Circulating Fibroblast Growth Factor 21 Is A Sensitive Biomarker for Severe Ischemia/reperfusion Injury in Patients with Liver Transplantation Targeted Metabolomics of Serum Acylcarnitines Evaluates Hepatoprotective Effect of Wuzhi Tablet (Schisandra sphenanthera Extract) against Acute Acetaminophen Toxicity.Loss of 5-lipoxygenase activity protects mice against paracetamol-induced liver toxicity Manganese superoxide dismutase deficiency triggers mitochondrial uncoupling and the Warburg effect.Metabolomics: an essential tool to understand the function of peroxisome proliferator-activated receptor alpha.PPARs modulate cardiac metabolism and mitochondrial function in diabetes.Fenofibrate/simvastatin fixed-dose combination in the treatment of mixed dyslipidemia: safety, efficacy, and place in therapy.c9,t11-Conjugated linoleic acid ameliorates steatosis by modulating mitochondrial uncoupling and Nrf2 pathway.Peroxisome Proliferator Activator Receptor (PPAR)- γ Ligand, but Not PPAR- α , Ameliorates Cyclophosphamide-Induced Oxidative Stress and Inflammation in Rat Liver.Peroxisome proliferator-activated receptors and Alzheimer's disease: hitting the blood-brain barrier.Site-specific antioxidative therapy for prevention of atherosclerosis and cardiovascular disease.LC-MS-based metabolomics: an update.The protection of glycyrrhetinic acid (GA) towards acetaminophen (APAP)-induced toxicity partially through fatty acids metabolic pathway.Inhibition of JNK signalling mediates PPARα-dependent protection against intrahepatic cholestasis by fenofibrate.PPARα activation sensitizes cancer cells to epigallocatechin-3-gallate (EGCG) treatment via suppressing heme oxygenase-1.Dual action of peroxisome proliferator-activated receptor alpha in perfluorodecanoic acid-induced hepatotoxicity.Targeted metabolomic profiling indicates structure-based perturbations in serum phospholipids in children with acetaminophen overdose.A Network Pharmacology-Based Study on the Hepatoprotective Effect of Fructus Schisandrae.A Biomedical Investigation of the Hepatoprotective Effect of Radix salviae miltiorrhizae and Network Pharmacology-Based Prediction of the Active Compounds and Molecular Targets.Acetaminophen-Induced Liver Injury Alters the Acyl Ethanolamine-Based Anti-Inflammatory Signaling System in Liver.Biochemical targets of drugs mitigating oxidative stress via redox-independent mechanisms.Downregulation of uncoupling protein-2 by genipin exacerbates diabetes-induced kidney proximal tubular cells apoptosis.How the mitochondrion was shaped by radical differences in substrates: what carnitine shuttles and uncoupling tell us about mitochondrial evolution in response to ROS.Alleviation of Toxicity Caused by Overactivation of Pparα through Pparα-Inducible miR-181a2.Identification and Characterization of Fenofibrate-Induced Liver Injury.Mitochondrial uncoupling proteins: subtle regulators of cellular redox signaling.Fenofibrate protects against acute myocardial I/R injury in rat by suppressing mitochondrial apoptosis as decreasing cleaved caspase-9 activation.Hepatocyte-specific PPARA expression exclusively promotes agonist-induced cell proliferation without influence from nonparenchymal cells.Role of the lipid-regulated NF-κB/IL-6/STAT3 axis in alpha-naphthyl isothiocyanate-induced liver injury.

P2860

Q28077397-E05F862F-8FE1-4B9C-B025-B9C1D2195567 Q28087473-4319BCAC-0294-46E6-9F8D-DBAE8639E2D2 Q29248254-5E372DCC-53FA-483F-873D-C6557D37EBBB Q30912007-257959B2-1729-40D2-934B-4D8674CF0718 Q33631584-BADF9A9A-B02A-402D-9E99-D425BAC582F3 Q33709930-F7C7B7C0-7DCB-4943-A2FB-628AC1EF3832 Q33845470-7BA8D5E8-377F-4066-8302-260ED1E7434A Q33959032-2E04AC8C-4563-4A91-9DAE-F66414AD39BB Q35224589-00311D2B-F0CA-471E-AAFE-CDD8CE5B88B7 Q35493627-6E91D05D-C515-413E-BC25-3B55F43EC1B6 Q36387273-263E8FFA-AD79-4EE7-977F-3D67582C8D74 Q36500607-B485F5AF-0424-4874-A475-A6DB4F5A4D09 Q36619354-25CF7B34-D568-429B-9979-EFD1E9D7369F Q36744182-03375E66-9F00-4517-BD40-D97BD88F1CC5 Q36879121-A559653B-DB19-492E-8E6D-53CE1DD6ED29 Q36949274-A7E2F3DA-90B1-44F6-BE90-A25F5692B227 Q37576286-AC054077-80E1-4E45-87E3-1F57F40408AD Q37653029-89CC595A-08A0-489B-8CA7-34680B6C2C99 Q37716350-FBE37D86-F6DB-4D49-BF21-87308488FE36 Q37717916-FFA140E1-F5B4-4193-A6D3-F14B41DEA28E Q38089668-F3C4E7D2-CE61-4A9C-882D-A3B45A555C2E Q38112118-F240864E-43D8-4FEC-8031-6C4038FF4877 Q38202881-9FE3A5AA-5195-4723-8F95-8EDB4F4EA151 Q38613194-73B4A8A1-8F6D-4B76-8D85-EFBFA6357E70 Q38711012-3754D13C-0BA3-40CB-86DF-C539C8FEFE0C Q39032412-8ECC2B50-F9B5-4A72-BDA8-EC3DA4E7222D Q39655011-BCD71AB3-464F-4804-AA28-EFB1C3CC707C Q41679331-E568CC08-0C18-4891-8D83-EEC7272C59DD Q41928784-E3422AE2-07B4-4D30-A975-1FDB091144EA Q42140906-EA2A764B-FE35-4ED3-9E61-74AC948A6A14 Q45329823-1416A220-1EFD-4672-BCBB-65A6F03F6A73 Q46269173-22A87F20-70D3-432E-8BF6-A01C444185FE Q46874528-FCC6E4B6-21CF-4D7B-9C61-5EC24C77B905 Q46891685-1DBAD915-E6BA-40AC-9B49-FCF3BE579EEF Q47099331-F373F900-65DE-40DB-B8EC-6AC9FC290A3A Q47422605-A92BE10D-F114-4C21-ABEF-875CDED743FB Q47722955-D31F6071-FF21-4735-91ED-88863A4681D8 Q50958710-CA7C9C0D-8A05-410C-8A6A-2DB464313817 Q51194324-2BA7EB08-0F67-4B2E-AFC4-1C360F48A501 Q51323656-F837AAA9-2289-42D0-8C3E-B2D7030A6F37

P2860

Peroxisome proliferator-activated receptor alpha induction of uncoupling protein 2 protects against acetaminophen-induced liver toxicity.

http://www.wikidata.org/entity/Q36044209

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

Peroxisome proliferator-activa ...... nophen-induced liver toxicity.

@ast

Peroxisome proliferator-activa ...... nophen-induced liver toxicity.

@en

type

label

Peroxisome proliferator-activa ...... nophen-induced liver toxicity.

@ast

Peroxisome proliferator-activa ...... nophen-induced liver toxicity.

@en

prefLabel

Peroxisome proliferator-activa ...... nophen-induced liver toxicity.

@ast

Peroxisome proliferator-activa ...... nophen-induced liver toxicity.

@en

P1433

Q36044209-9D519CF0-27FE-4E07-AD7E-C94BA86E2B4E

P1476

Q36044209-4A31E8B5-696C-4944-96DB-0FCD8599A2C9

P2093

Q36044209-16D7D9C3-9DB7-4521-8B9D-490C7B42B151

Q36044209-334C9E86-B35A-44E9-BFEF-F594945D897E

Q36044209-B7D1BDBF-56E5-4CFB-9AE1-819DC37CA99A

Q36044209-EF743567-CD89-4876-A5BE-0B6F6439E0DE

P2860

Q36044209-0365A9C8-FFD4-4078-8938-792E0121F08A

Q36044209-169B6574-BF19-4A2A-AA8A-5BD2DD5B2407

Q36044209-1EAC8992-8B84-4099-858C-39D05E272DF6

Q36044209-2EAFBF7A-ED84-4664-825E-86B54CDE3489

Q36044209-3277C558-6445-4FF0-8A0E-E93EC77E2AF4

Q36044209-36CDBDEE-B338-41D6-A2F6-FF7C7EDCA85B

Q36044209-3865CD2B-2F6D-4C72-8E83-71A42CB5D6CE

Q36044209-3F1A58CF-CC36-44D8-BA62-890DCA81A12C

Q36044209-45C8C2E7-7B41-42F3-9738-15F525A2F0F3

Q36044209-4EF9648D-70EA-4C24-BAEE-7AAFE3FDD8C3

P304

Q36044209-523C43F6-2158-4EE0-9749-0DAC8F977B73

P31

Q36044209-98285B92-7974-4AF1-B49F-477A7B6122D4

P356

Q36044209-2405EBA6-07E3-4C48-9582-5AAA2292CDFB

P407

Q36044209-907CC67B-EFDF-4635-AEDB-E74E682AE40B

P433

Q36044209-00C90A67-E81F-4375-A703-3D49AB7D7696

P478

Q36044209-DDFA8F63-DA09-4CE4-B185-6D161CD802E2

P50

Q36044209-02099649-EE0E-4488-9C2E-FF3A7C347E6A

P577

Q36044209-06728FD4-F2F9-4CBA-8A91-02A996C02581

P5875

Q36044209-0BC26BF4-D3EB-4915-9042-4F1F094FB302

P698

Q36044209-014E758D-623A-4988-BD56-74C6ECA101A3

P932

Q36044209-A48D127F-85A1-4680-941C-4D292434E032

P356

P1433

P1476

Peroxisome proliferator-activa ...... inophen-induced liver toxicity

@en

P2093

Frank J Gonzalez

http://www.w3.org/2001/XMLSchema#string

Kristopher W Krausz

http://www.w3.org/2001/XMLSchema#string

Tsutomu Matsubara

http://www.w3.org/2001/XMLSchema#string

Yatrik M Shah

http://www.w3.org/2001/XMLSchema#string

P2860

Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting

Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators

Mitochondrial uncoupling protein 2 structure determined by NMR molecular fragment searching

Peroxisome proliferator-activated receptor alpha target genes

Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor alpha (PPARalpha)

c-Jun N-terminal kinase (JNK)-dependent acute liver injury from acetaminophen or tumor necrosis factor (TNF) requires mitochondrial Sab protein expression in mice

Peroxisome proliferator-activated receptor alpha-null mice lack resistance to acetaminophen hepatotoxicity following clofibrate exposure.

Acetaminophen-induced nephrotoxicity: pathophysiology, clinical manifestations, and management.

The 'novel' 'uncoupling' proteins UCP2 and UCP3: what do they really do? Pros and cons for suggested functions.

Peroxisome proliferator-activated receptor alpha regulates a microRNA-mediated signaling cascade responsible for hepatocellular proliferation

P304

281-290

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1002/HEP.25645

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

56

http://www.w3.org/2001/XMLSchema#string

P50

Andrew Patterson

P577

2012-06-06T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

221817666

http://www.w3.org/2001/XMLSchema#string

P698

22318764

http://www.w3.org/2001/XMLSchema#string

P932

3378765

http://www.w3.org/2001/XMLSchema#string