In vivo role of focal adhesion kinase in regulating pancreatic β-cell mass and function through insulin signaling, actin dynamics, and granule trafficking
about
Hyaluronan: A Mediator of Islet Dysfunction and Destruction in Diabetes?Redox homeostasis in pancreatic β cellsSignaling mechanisms of glucose-induced F-actin remodeling in pancreatic islet β cellsNon-muscle myosin IIA is involved in focal adhesion and actin remodelling controlling glucose-stimulated insulin secretion.Myt3 Mediates Laminin-V/Integrin-β1-Induced Islet-Cell Migration via TgfbiCompliant 3D microenvironment improves β-cell cluster insulin expression through mechanosensing and β-catenin signaling.Possible protective effect of membrane lipid rafts against interleukin-1β-mediated anti-proliferative effect in INS-1 cells.BAG3 regulates formation of the SNARE complex and insulin secretionPTEN, a widely known negative regulator of insulin/PI3K signaling, positively regulates neuronal insulin resistance.Antiaging Gene Klotho Attenuates Pancreatic β-Cell Apoptosis in Type 1 Diabetes.A p21-activated kinase (PAK1) signaling cascade coordinately regulates F-actin remodeling and insulin granule exocytosis in pancreatic β cells.Modulating the dysregulated migration of pulmonary arterial hypertensive smooth muscle cells with motif mimicking cell permeable peptidesSecretagogin affects insulin secretion in pancreatic β-cells by regulating actin dynamics and focal adhesionRetinoblastoma tumor suppressor protein in pancreatic progenitors controls α- and β-cell fate.Interleukin-1 signaling contributes to acute islet compensationCB1 cannabinoid receptors couple to focal adhesion kinase to control insulin release.FAK signalling controls insulin sensitivity through regulation of adipocyte survival.Rb and p107 are required for alpha cell survival, beta cell cycle control and glucagon-like peptide-1 action.The skeleton in the closet: actin cytoskeletal remodeling in β-cell function.Role and impact of the extracellular matrix on integrin-mediated pancreatic β-cell functions.GLP-1(28-36) improves β-cell mass and glucose disposal in streptozotocin-induced diabetic mice and activates cAMP/PKA/β-catenin signaling in β-cells in vitro.Critical role of β1 integrin in postnatal beta-cell function and expansionNeurotrophin Signaling Is Required for Glucose-Induced Insulin Secretion.The RhoGAP Stard13 controls insulin secretion through F-actin remodeling.
P2860
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P2860
In vivo role of focal adhesion kinase in regulating pancreatic β-cell mass and function through insulin signaling, actin dynamics, and granule trafficking
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
In vivo role of focal adhesion ...... amics, and granule trafficking
@ast
In vivo role of focal adhesion ...... amics, and granule trafficking
@en
type
label
In vivo role of focal adhesion ...... amics, and granule trafficking
@ast
In vivo role of focal adhesion ...... amics, and granule trafficking
@en
prefLabel
In vivo role of focal adhesion ...... amics, and granule trafficking
@ast
In vivo role of focal adhesion ...... amics, and granule trafficking
@en
P2093
P2860
P50
P356
P1433
P1476
In vivo role of focal adhesion ...... amics, and granule trafficking
@en
P2093
Aliya F Spigelman
Catherine Hajmrle
Cynthia T Luk
Diana Choi
Erica P Cai
Herbert Y Gaisano
Marina Casimir
Stephanie A Schroer
Xiao Qing Dai
P2860
P304
P356
10.2337/DB11-1344
P407
P577
2012-04-12T00:00:00Z