Insulin granule recruitment and exocytosis is dependent on p110gamma in insulinoma and human beta-cells
about
Phosphoinositides: tiny lipids with giant impact on cell regulationRemodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopyClass II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic beta cellsDeSUMOylation Controls Insulin Exocytosis in Response to Metabolic Signals.Mitochondrial metabolism of pyruvate is essential for regulating glucose-stimulated insulin secretionInsulin secretion induced by glucose-dependent insulinotropic polypeptide requires phosphatidylinositol 3-kinase γ in rodent and human β-cells.Mechanism of glucose-6-phosphate dehydrogenase-mediated regulation of coronary artery contractility.PI3Kγ within a nonhematopoietic cell type negatively regulates diet-induced thermogenesis and promotes obesity and insulin resistance.Islet cholesterol accumulation due to loss of ABCA1 leads to impaired exocytosis of insulin granules.α-Synuclein binds the K(ATP) channel at insulin-secretory granules and inhibits insulin secretion.In vivo role of focal adhesion kinase in regulating pancreatic β-cell mass and function through insulin signaling, actin dynamics, and granule traffickingProtein kinase C-delta deficiency perturbs bone homeostasis by selective uncoupling of cathepsin K secretion and ruffled border formation in osteoclastsRas-related C3 botulinum toxin substrate 1 (RAC1) regulates glucose-stimulated insulin secretion via modulation of F-actin.PI3 kinases p110α and PI3K-C2β negatively regulate cAMP via PDE3/8 to control insulin secretion in mouse and human islets.Intraislet SLIT-ROBO signaling is required for beta-cell survival and potentiates insulin secretion.Class II phosphoinositide 3-kinase C2alpha: what we learned so farImpact of gain-of-function mutations in the low-density lipoprotein receptor-related protein 5 (LRP5) on glucose and lipid homeostasis.Role of phosphatidylinositol-4,5-bisphosphate 3-kinase signaling in vesicular trafficking.Triton X-100 inhibits L-type voltage-operated calcium channels.Involvement of phosphoinositide 3-kinase gamma in angiogenesis and healing of experimental myocardial infarction in mice.R-spondin-1 is a novel beta-cell growth factor and insulin secretagogueInhibition of beta-cell sodium-calcium exchange enhances glucose-dependent elevations in cytoplasmic calcium and insulin secretion.Involvement of phosphoinositide 3-kinase and PTEN protein in mechanism of activation of TRPC6 protein in vascular smooth muscle cells.SUMOylation regulates insulin exocytosis downstream of secretory granule docking in rodents and humans.A Comprehensive Survey of the Roles of Highly Disordered Proteins in Type 2 Diabetes.Maternal zinc restriction affects postnatal growth and glucose homeostasis in rat offspring differently depending upon adequacy of their nutrient intake.Excess cholesterol inhibits glucose-stimulated fusion pore dynamics in insulin exocytosis.
P2860
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P2860
Insulin granule recruitment and exocytosis is dependent on p110gamma in insulinoma and human beta-cells
description
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
im September 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/09/01)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/09/01)
@nl
наукова стаття, опублікована у вересні 2009
@uk
مقالة علمية (نشرت في سبتمبر 2009)
@ar
name
Insulin granule recruitment an ...... nsulinoma and human beta-cells
@ast
Insulin granule recruitment an ...... nsulinoma and human beta-cells
@en
Insulin granule recruitment an ...... nsulinoma and human beta-cells
@nl
type
label
Insulin granule recruitment an ...... nsulinoma and human beta-cells
@ast
Insulin granule recruitment an ...... nsulinoma and human beta-cells
@en
Insulin granule recruitment an ...... nsulinoma and human beta-cells
@nl
prefLabel
Insulin granule recruitment an ...... nsulinoma and human beta-cells
@ast
Insulin granule recruitment an ...... nsulinoma and human beta-cells
@en
Insulin granule recruitment an ...... nsulinoma and human beta-cells
@nl
P2093
P2860
P3181
P356
P1433
P1476
Insulin granule recruitment an ...... nsulinoma and human beta-cells
@en
P2093
Brandon J. Ball
Gary M. Pigeau
Jelena Kolic
Jocelyn E. Manning Fox
Michael B. Hoppa
Patrick E. MacDonald
Thomas Rückle
Ying W. Wang
P2860
P304
P3181
P356
10.2337/DB08-1371
P407
P577
2009-09-01T00:00:00Z